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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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A141428-50mg
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50mg |
3
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$103.90
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A141428-250mg
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250mg |
3
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$344.90
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Potent antioxidant agent. PPARα agonist and PPARγ antagonist.
| Synonyms | DTXSID00893777 | Natupink | UNII-8XPW32PR7I | .beta.-Carotene-4,4'-dione, 3,3'-dihydroxy-, all-trans- | BCP05821 | CHEBI:40968 | LMPR01070263 | NSC-635689 | ASTAXANTHIN [WHO-DD] | 3S,3'S-Astaxanthin | Astaxanthin | SCHEMBL20047 | M01303 | Ovoester |
|---|---|
| Specifications & Purity | ≥95%(HPLC),mixture of cis and trans |
| Biochemical and Physiological Mechanisms | Astaxanthin is a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity. Astaxanthin protects against oxidative stress, inhibiting NF-KB, suppressing pro-inflammatory genes and suppressing production of pro-inflammatory |
| Storage Temp | Protected from light,Store at -20°C,Argon charged |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Astaxanthin (AST) is a red dietary carotenoid. It is mainly found in aquatic animals and microalgae, such as Haematococcus pluvialis and Chlorella zofingiensis. Application: |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Prenol lipids |
| Subclass | Tetraterpenoids |
| Intermediate Tree Nodes | Carotenoids |
| Direct Parent | Xanthophylls |
| Alternative Parents | Cyclohexenones Secondary alcohols Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aliphatic homomonocyclic compounds |
| Substituents | Xanthophyll - Cyclohexenone - Cyclic ketone - Secondary alcohol - Ketone - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as xanthophylls. These are carotenoids containing an oxygenated carotene backbone. Carotenes are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family. Xanthophylls arise by oxygenation of the carotene backbone. |
| External Descriptors | C40 isoprenoids (tetraterpenes) |
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| ALogP | 10.3 |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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| IUPAC Name | (6S)-6-hydroxy-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethyl-3-oxocyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,4,4-trimethylcyclohex-2-en-1-one |
|---|---|
| INCHI | InChI=1S/C40H52O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24,35-36,41-42H,25-26H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,27-15+,28-16+,29-19+,30-20+/t35-,36-/m0/s1 |
| InChIKey | MQZIGYBFDRPAKN-UWFIBFSHSA-N |
| Smiles | CC1=C(C(CC(C1=O)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(C(=O)C(CC2(C)C)O)C)C)C |
| Isomeric SMILES | CC1=C(C(C[C@@H](C1=O)O)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C2=C(C(=O)[C@H](CC2(C)C)O)C)\C)\C)/C)/C |
| WGK Germany | 3 |
| Alternate CAS | 7542-45-2 |
| Molecular Weight | 596.84 |
| Reaxy-Rn | 11489489 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11489489&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 14, 2025 | A141428 | |
| Certificate of Analysis | Mar 14, 2025 | A141428 | |
| Certificate of Analysis | Oct 18, 2024 | A141428 | |
| Certificate of Analysis | Jan 12, 2022 | A141428 | |
| Certificate of Analysis | Jan 12, 2022 | A141428 | |
| Certificate of Analysis | Jan 12, 2022 | A141428 | |
| Certificate of Analysis | Apr 19, 2021 | A141428 |
| Sensitivity | light & air & heat sensitive |
|---|---|
| Melt Point(°C) | 215-216°C |
| Molecular Weight | 596.800 g/mol |
| XLogP3 | 10.300 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 10 |
| Exact Mass | 596.387 Da |
| Monoisotopic Mass | 596.387 Da |
| Topological Polar Surface Area | 74.600 Ų |
| Heavy Atom Count | 44 |
| Formal Charge | 0 |
| Complexity | 1340.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 9 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 9 |
| Covalently-Bonded Unit Count | 1 |
Starting at $134.90
Starting at $67.90
Starting at $205.90
| 1. Lei Diao, Wenjie Liu, Yawei Xu, Bin Zhang, Lingnan Meng, Rui Yin, Huijie Chen. (2024) New insights into micro-algal astaxanthin's effect on deoxynivalenol-induced spleen lymphocytes pyroptosis in Cyprinus carpio: Involving mitophagy and mtROS-NF-κB-dependent NLRP3 inflammasome. FISH & SHELLFISH IMMUNOLOGY, 144 (109259). |
| 2. Pengjing Zhang, Yuanda Sun, Yitong Hou, Haitao Wang, Mingqian Tan. (2024) Fabrication of novel W/O/W emulsion gels using beeswax stabilized W/O: Preparation, characterization and co-delivery of phycocyanin and astaxanthin. Food Bioscience, 57 (103536). |
| 3. Zi-Xu Zhang, Lu-Wei Xu, Ying-Shuang Xu, Jin Li, Wang Ma, Xiao-Man Sun, He Huang. (2024) Integration of genetic engineering and multi-factor fermentation optimization for co-production of carotenoid and DHA in Schizochytrium sp. BIORESOURCE TECHNOLOGY, 394 (130250). |
| 4. Lei Diao, Meiqi Ding, Hongzhen Sun, Yawei Xu, Rui Yin, Huijie Chen. (2023) Micro-algal astaxanthin ameliorates polystyrene microplastics-triggered necroptosis and inflammation by mediating mitochondrial Ca2+ homeostasis in carp’s head kidney lymphocytes (Cyprinus carpio L.). FISH & SHELLFISH IMMUNOLOGY, 143 (109205). |
| 5. Swagata Dutta, S.P. Jeevan Kumar, Rintu Banerjee. (2023) A comprehensive review on astaxanthin sources, structure, biochemistry and applications in the cosmetic industry. Algal Research-Biomass Biofuels and Bioproducts, 74 (103168). |
| 6. Dong Su, Junkui Miao, Xiaofang Liu, Xixi Wang, Yuan Yu, Kailiang Leng, Yueqin Yu. (2023) Separation and concentration of phospholipids and glycerides from ethanol extraction of krill by hydration and solvent partitioning. SEPARATION AND PURIFICATION TECHNOLOGY, 317 (123900). |
| 7. Yingyuan Zhao, Zhaoxuan Wang, Shuxian Liu, Shiying Xie, Yinchun Xie, Ruifang Li, Hiroaki Oda. (2023) Lyoprotectant Formulation and Optimization of the J-Aggregates Astaxanthin/BSA/Chitosan Nanosuspension. Biomolecules, 13 (3): (496). |
| 8. Xin-Nan Teng, Shu-Chang Wang, Liaqat Zeb, Yue-Sheng Dong, Zhi-Long Xiu. (2023) Two-Step Enzymolysis of Antarctic Krill for Simultaneous Preparation of Value-Added Oil and Enzymolysate. Marine Drugs, 21 (1): (47). |
| 9. Yu Fei, Chen Jiaxin, Wei Zizhan, Zhu Pingchuan, Qing Qing, Li Bangda, Chen Huimin, Lin Weiying, Yang Hua, Qi Zhongquan, Hong Xuehui, Chen Xiao Dong. (2022) Preparation of carrier-free astaxanthin nanoparticles with improved antioxidant capacity. Frontiers in Nutrition, 9 |
| 10. Sun Xixi, Yuan Yujie, Chen Qitong, Nie Shiqi, Guo Jiaxuan, Ou Zutian, Huang Min, Deng Zixin, Liu Tiangang, Ma Tian. (2022) Metabolic pathway assembly using docking domains from type I cis-AT polyketide synthases. Nature Communications, 13 (1): (1-12). |
| 11. Zhi-Ang Liu, Ya-Nan Zuo, Yinghui Xia, Jing Sun, Shuyun Zhu. (2022) Enhanced detection of ascorbic acid with cascaded fluorescence recovery of a dual-nanoquencher system. Analytical Methods, 14 (37): (3632-3637). |
| 12. Shi Zhihui, He Xiaoxian, Zhang Hailiang, Guo Xuena, Cheng Yanfei, Liu Xuelian, Wang Zhaoyue, He Xiuping. (2022) Whole Genome Sequencing and RNA-seq-Driven Discovery of New Targets That Affect Carotenoid Synthesis in Phaffia rhodozyma. Frontiers in Microbiology, 13 |
| 13. Hang-Zhi Zhu, Shan Jiang, Jun-Jie Wu, Xue-Rong Zhou, Peng-Yang Liu, Feng-Hong Huang, Xia Wan. (2022) Production of High Levels of 3S,3′S-Astaxanthin in Yarrowia lipolytica via Iterative Metabolic Engineering. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (8): (2673–2683). |
| 14. Lijun Ding, Jie Yang, Kangrui Yin, Hao Cheng, Jing Li, Changhu Xue. (2022) The spatial arrangement of astaxanthin in bilayers greatly influenced the structural stability of DPPC liposomes. COLLOIDS AND SURFACES B-BIOINTERFACES, 212 (112383). |
| 15. Shujie Wang, Kefei Chen, Guoqin Liu. (2022) Monoglyceride oleogels for lipophilic bioactive delivery – Influence of self-assembled structures on stability and in vitro bioaccessibility of astaxanthin. FOOD CHEMISTRY, 375 (131880). |
| 16. Zhipeng Qi, Xianyu Fan, Chunyi Zhu, Dongsheng Chang, Jianjun Pei, Linguo Zhao. (2021) Overexpression and Characterization of a Novel Plant Carotenoid Cleavage Dioxygenase 1 from Morus notabilis. CHEMISTRY & BIODIVERSITY, 19 (2): (e202100735). |
| 17. Ru Song, Yu Qi, Zhe Jia, Xinyan Liu, Rongbian Wei. (2020) Astaxanthin-loaded zein/calcium alginate composite microparticles: Characterization, molecular interaction and release kinetics in fatty food simulant system. LWT-FOOD SCIENCE AND TECHNOLOGY, 134 (110146). |
| 18. Jianfeng Mei, Xiaoyun Zhao, Yu Yi, Yanlu Zhang, Xudong Wang, Guoqing Ying. (2020) Preparation of astaxanthin by lipase-catalyzed hydrolysis from its esters in a slug-flow microchannel reactor. PROCESS BIOCHEMISTRY, 98 (241). |
| 19. Xujian Qiu, Yumeng Wu, Shengjun Chen, Lechang Sun, Guangming Liu, Hong Lin. (2020) Oxidative Stability and Browning Development of Semi-dried Shrimp (Acetes chinensis) with Different Salt Contents and Packaging Methods Stored at Refrigerated Temperature. FOOD SCIENCE AND TECHNOLOGY RESEARCH, |
| 20. Yunchang Fan, Zeyu Niu, Chen Xu, Lei Yang, Feiyang Chen, He Zhang. (2019) Biocompatible protic ionic liquids-based microwave-assisted liquid-solid extraction of astaxanthin from Haematococcus pluvialis. INDUSTRIAL CROPS AND PRODUCTS, 141 (111809). |
| 21. Yanbin Wang, Yao Liu, Yuchen Li, Binbing Liu, Pei Wu, Shancai Xu, Huaizhang Shi. (2019) Protective effects of astaxanthin on subarachnoid hemorrhage-induced early brain injury: Reduction of cerebral vasospasm and improvement of neuron survival and mitochondrial function. ACTA HISTOCHEMICA, 121 (56). |
| 22. Zhi-Wei Liu, Xin-An Zeng, Jun-Hu Cheng, De-Bao Liu, Rana Muhammad Aadil. (2018) The efficiency and comparison of novel techniques for cell wall disruption in astaxanthin extraction from Haematococcus pluvialis. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 53 (9): (2212-2219). |
| 23. Dan Xie, Hongyan Mu, Tianpei Tang, Xiaosan Wang, Wei Wei, Jun Jin, Xingguo Wang, Qingzhe Jin. (2018) Production of three types of krill oils from krill meal by a three-step solvent extraction procedure. FOOD CHEMISTRY, 248 (279). |
| 24. Tian Ma, Yuanjie Zhou, Xiaowei Li, Fayin Zhu, Yongbo Cheng, Yi Liu, Zixin Deng, Tiangang Liu. (2015) Genome mining of astaxanthin biosynthetic genes from Sphingomonas sp. ATCC 55669 for heterologous overproduction in Escherichia coli. Biotechnology Journal, 11 (2): (228-237). |
| 25. Jingwen Han, Jiamin Ye, Jiacheng Shi, Yueyue Fan, Xue Yuan, Ruiyan Li, Gaoli Niu, Muhammad Abubakar, Yong Kang, Xiaoyuan Ji. (2024) A Programmable Oral Nanomotor Microcapsule for the Treatment of Inflammatory Bowel Disease. ADVANCED FUNCTIONAL MATERIALS, (2413261). |
| 26. Shujie Cheng, Shimin Wu. (2024) A shelf life prediction method for butter based on the effects of β-carotene on colour and oxidative stability. INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY, 77 (3): (961-972). |
| 27. Xiuping Lin, Chang-sheng Shao, Shereen M. Elsherbiny, Qing Huang. (2024) Astaxanthin attenuates UV-irradiation aging process via activating JNK-1/DAF-16 in Caenorhabditis elegans. PHOTOCHEMISTRY AND PHOTOBIOLOGY, |
| 28. Yahui Wu, Mona Alrasheed Bashir, Changsheng Shao, Han Wang, Jianxia Zhu, Qing Huang. (2024) Astaxanthin targets IL-6 and alleviates the LPS-induced adverse inflammatory response of macrophages. Food & Function, |
| 29. Shujie Cheng, Shimin Wu, Jianqiang Lan. (2024) Beta-carotene and astaxanthin inhibit the formation of polycyclic aromatic hydrocarbons and oxygenated polycyclic aromatic hydrocarbons in butter during heat treatment. INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY, |
| 30. Shujie Wang, Yuyue Qin, Yaping Liu, Guoqin Liu, Guiguang Cheng, Thanapop Soteyome. (2024) Controlling release of astaxanthin in β-sitosterol oleogel-based emulsions via different self-assembled mechanisms and composition of the oleogelators. FOOD RESEARCH INTERNATIONAL, 186 (114350). |
| 31. Na Li, Yefan Wang, Zhifeng Tan, Yunpeng Xu, Xiaoyang Liu, Yuxin Liu, Dayong Zhou, Deyang Li. (2024) Effect of ultra-high pressure heat-assisted technology combined with L-cysteine on the color of ready-to-eat shrimp during storage. FOOD CHEMISTRY, 460 (140634). |
| 32. Xiaorong Huang, Ru Tan, Zhi Geng, Tao Zhang, Guangpeng Feng, Gang Yang, Feng Zhao, Ping Zhuang. (2024) Effects of Antarctic Krill Meal in Diet on Reproductive Performance and Embryo Quality of Eriocheir sinensis. AQUACULTURE NUTRITION, 2024 (9936529). |
| 33. Xue Qin, Menghao Yang, Xiaolin Wang, Haoqi Xiao, Chaoyue Cao, Jiawen Chai, Weijun Pang. (2024) Effects of Astaxanthin on oxidative stress of sows and piglet growth performances. Livestock Science, 285 (105500). |
| 34. Yuanzhao Wu, Ye'anlun Zhu, An Cheng, Weixuan Yao, Binjie Wang, Ruonan Zheng, Jiye Wang. (2025) Effects of tefluthrin exposure on early life stages in zebrafish: Insights into cardiac and skeletal development, oxidative stress and apoptosis. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 292 (117931). |
| 35. Jiayan Du, Youtong Bao, Jingyuan Zhu, Xueqing Pang, Depeng Ren, Xinjian Yin, Pingping Zhou. (2025) Engineering of β-carotene hydroxylase for enhanced astaxanthin production in Saccharomyces cerevisiae. BIOCHEMICAL ENGINEERING JOURNAL, 219 (109722). |
| 36. Chao Wang, Wang Ma, Luwei Xu, Zhiyun Wei, Ke Tang, Jingwen Zhou, Jian Chen. (2024) Integrative metabolic engineering and cellular organelle engineering for improving biosynthesis of flavonoid compounds in saccharomyces cerevisiae. Food Bioscience, (103996). |
| 37. Na Li, Xin Fan, Yefan Wang, Kexin Zhang, Rong Liu, Yunpeng Xu, Zhifeng Tan, Wensi Xu, Dayong Zhou, Deyang Li. (2024) Investigation of isomerization and oxidation of astaxanthin in ready-to-eat Litopenaeus vannamei during accelerated storage. FOOD RESEARCH INTERNATIONAL, 195 (114983). |
| 38. Liu Kangjing, Tian Xueying, Fei Siyuan, Song Yukun, Abd El-Aty A. M., Tan Mingqian. (2025) Macrophage and mitochondrion dual-targeting astaxanthin nanoparticles prepared by Maillard reaction for colonic inflammation alleviation. Marine Life Science & Technology, (1-14). |
| 39. Kaixuan Ke, Ling Guo, Zhipeng Qi, Dou Dou, Han Ma, Xianying Fang, Linguo Zhao. (2024) Molecular cloning, expression, and biochemical characterization of carotenoid cleavage dioxygenase 1 (LbCCD1) from Lycium barbarum. Molecular Catalysis, 569 (114561). |
| 40. Lijuan Zhang, Shan Sun, Wentao Su, Mingqian Tan. (2025) Preventive effect of sea bass protein-based high internal phase Pickering emulsion loaded with astaxanthin on DEHP-induced liver lipid metabolism disorder. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 292 (139190). |
| 41. Wenxuan Jiang, Xiangrong Deng, Lanxian Qin, Dahai Jiang, Mengqi Lu, Kai Chen, Manqi Yang, Liangliang Zhang, Jianchun Jiang, Liming Lu. (2024) Research on the Cell Wall Breaking and Subcritical Extraction of Astaxanthin from Phaffia rhodozyma. MOLECULES, 29 (17): (4201). |
| 42. Xiaoting Yu, Yannan Chen, Mingqian Tan. (2024) ROS-responsive carboxymethyl chitosan nanoparticles loaded with astaxanthin for alleviating oxidative damage in intestinal cells. COLLOIDS AND SURFACES B-BIOINTERFACES, (113960). |
| 43. Yafang Li, Jia Wei, Xiaofang Liang, Jiangping Wang, Sisi Yan, Lemei Zhu, Zhen Ding, Chunhua Zhan, Xiaoya Ren, Fei Yang. (2025) Sphingopyxis sp. YF1 and metabolite astaxanthin alleviate MC-LR-induced kidney injury. PROCESS SAFETY AND ENVIRONMENTAL PROTECTION, 197 (106982). |
| 44. Jia Jianping, Chen Zhitao, Li Qingqing, Li Feifei, Liu Siru, Bao Guoliang. (2024) The enhancement of astaxanthin production in Phaffia rhodozyma through a synergistic melatonin treatment and zinc finger transcription factor gene overexpression. Frontiers in Microbiology, 15 |