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Astaxanthin - ≥98% (HPLC),mixture of cis and trans, high purity , Antioxidant, anti-inflammatory and antiapoptotic activities, CAS No.472-61-7, Antioxidant, anti-inflammatory and antiapoptotic activities

    Grade & Purity:
  • ≥98%(HPLC)
  • mixture of cis and trans
In stock
Item Number
A114383
Grouped product items
SKU Size
Availability
Price Qty
A114383-50mg
50mg
3
$134.90
A114383-250mg
250mg
3
$530.90

Basic Description

Synonyms DTXSID00893777 | Natupink | UNII-8XPW32PR7I | .beta.-Carotene-4,4'-dione, 3,3'-dihydroxy-, all-trans- | BCP05821 | CHEBI:40968 | LMPR01070263 | NSC-635689 | ASTAXANTHIN [WHO-DD] | 3S,3'S-Astaxanthin | Astaxanthin | SCHEMBL20047 | M01303 | trans-Astaxanthi
Specifications & Purity ≥98%(HPLC), mixture of cis and trans
Biochemical and Physiological Mechanisms Astaxanthin is a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity. Astaxanthin protects against oxidative stress, inhibiting NF-KB, suppressing pro-inflammatory genes and suppressing production of pro-inflammatory
Storage Temp Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action Antioxidant, anti-inflammatory and antiapoptotic activities
Product Description

Astaxanthin (AST) is a red dietary carotenoid. It is mainly found in aquatic animals and microalgae, such as Haematococcus pluvialis and Chlorella zofingiensis.
Astaxanthin is a potent carotenoid antioxidant found in marine algae, red yeast and many other plant and animal sources. Animal studies indicate that it reduces blood glucose and ameliorates several parameters of the diabetic metabolic syndrome. It improves blood flow and vascular tone in models of hypertension. In vitro studies indicate that it upregulates connexin 43 and thus, may be chemopreventive against cancer.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Lipids and lipid-like molecules
Class Prenol lipids
Subclass Tetraterpenoids
Intermediate Tree Nodes Carotenoids
Direct Parent Xanthophylls
Alternative Parents Cyclohexenones  Secondary alcohols  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aliphatic homomonocyclic compounds
Substituents Xanthophyll - Cyclohexenone - Cyclic ketone - Secondary alcohol - Ketone - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as xanthophylls. These are carotenoids containing an oxygenated carotene backbone. Carotenes are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family. Xanthophylls arise by oxygenation of the carotene backbone.
External Descriptors C40 isoprenoids (tetraterpenes)

Product Properties

ALogP 10.3

Associated Targets(Human)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mus musculus (284745 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name (6S)-6-hydroxy-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethyl-3-oxocyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,4,4-trimethylcyclohex-2-en-1-one
INCHI InChI=1S/C40H52O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24,35-36,41-42H,25-26H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,27-15+,28-16+,29-19+,30-20+/t35-,36-/m0/s1
InChIKey MQZIGYBFDRPAKN-UWFIBFSHSA-N
Smiles CC1=C(C(CC(C1=O)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(C(=O)C(CC2(C)C)O)C)C)C
Isomeric SMILES CC1=C(C(C[C@@H](C1=O)O)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C2=C(C(=O)[C@H](CC2(C)C)O)C)\C)\C)/C)/C
WGK Germany 3
Alternate CAS 7542-45-2
Molecular Weight 596.84
Reaxy-Rn 11489489
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11489489&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot Number Certificate Type Date Item
I2425199 Certificate of Analysis Oct 11, 2024 A114383
I2425202 Certificate of Analysis Oct 10, 2024 A114383
I2425193 Certificate of Analysis Oct 09, 2024 A114383
I2412114 Certificate of Analysis Sep 23, 2024 A114383
J2227049 Certificate of Analysis Aug 16, 2024 A114383
J2227089 Certificate of Analysis Aug 13, 2024 A114383
A2402451 Certificate of Analysis Dec 14, 2023 A114383
A2402453 Certificate of Analysis Dec 14, 2023 A114383
A2127136 Certificate of Analysis Nov 14, 2022 A114383

Chemical and Physical Properties

Solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Sensitivity light and air sensitive
Melt Point(°C) 215-216°C
Molecular Weight 596.800 g/mol
XLogP3 10.300
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 10
Exact Mass 596.387 Da
Monoisotopic Mass 596.387 Da
Topological Polar Surface Area 74.600 Ų
Heavy Atom Count 44
Formal Charge 0
Complexity 1340.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 2
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 9
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 9
Covalently-Bonded Unit Count 1

Solution Calculators

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