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AS-85 - 98%, high purity , CAS No.2323623-80-7

COA

Grade & Purity:

≥98%

Cas Number: 2323623-80-7
Molecular Weight: 579.66

In stock

Item Number

A648027

Grouped product items
SKU	Size	Availability	Price
A648027-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$170.90
A648027-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$500.90
A648027-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$850.90

View related series

Epigenetics (1496) Histone Methyltransferase (190) Histone Modification (1379)

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	AS-85 is a potent ASH1L histone methyltransferase inhibitor ( IC 50 =0.6 µM) with anti-leukemic activity. AS-85 strongly binds to the ASH1L SET domain, with the K d value of 0.78u2009µM.
Storage Temp	Protected from light,Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	AS-85 is a potent ASH1L histone methyltransferase inhibitor ( IC 50 =0.6 µM) with anti-leukemic activity. AS-85 strongly binds to the ASH1L SET domain, with the K d value of 0.78 µM. In Vitro AS-85 inhibits the growth of leukemia cells (MV4;11, MOLM13, and KOPN8) harboring different MLL1 translocations, with GI 50 values ranging from 5 µM to 25 µM, and demonstrates no effect in K562 leukemia cells without MLL1 translocations. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Names and Identifiers

Smiles	O=C(C1CNC1)NCC2=CC3=C(C=C2)C(C4=CC=CC(C(N)=S)=C4)=CN3C5CCN(S(=O)(C(F)(F)F)=O)CC5
Molecular Weight	579.66

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