AR7 is a retinoic acid receptor α (RARα) antagonist.
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Product Description
Information
AR7 AR7 is a retinoic acid receptor α (RARα) antagonist.
application：
AR7 has been used:
• as chaperone-mediated autophagy (CMA) activator to study the activity of CMA in rat liver lysosomes
• as a CMA activator to study its effects on expression of DEAD-box helicase 3 X-linked (DDX3X), eukaryotic translation initiation factor 4A1 (EIF4A1), and eukaryotic translation initiation factor 4H (EIF4H) in cancer cells
• to study its effects on synuclein α (SNCA) oligomer levels in mature primary cortical neurons
This compound belongs to the class of organic compounds known as benzoxazines. These are organic compounds containing a benzene fused to an oxazine ring (a six-membered aliphatic ring with four carbon atoms, one oxygen atom, and one nitrogen atom).
External Descriptors
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1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
