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AN-2718 - 98%, high purity , CAS No.174672-06-1

COA

Grade & Purity:

≥98%

Cas Number: 174672-06-1
Molecular Weight: 168.39
PubChem CID: 11845944

In stock

Item Number

A413006

Grouped product items
SKU	Size	Availability	Price
A413006-5mg	5mg	3	$39.90
A413006-10mg	10mg	3	$49.90
A413006-25mg	25mg	2	$93.90
A413006-50mg	50mg	2	$149.90
A413006-100mg	100mg	2	$227.90
A413006-500mg	500mg	1	$569.90

Fungal Inhibitors

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Fungal (844)

Basic Description

Synonyms	5-chloro-1-hydroxy-3H-2,1-benzoxaborole \| EN300-117650 \| HMS3260B19 \| AC-36848 \| C7H6BClO2 \| 810U6C2DGG \| Z1198729424 \| BCP16819 \| MFCD18633195 \| UNII-810U6C2DGG \| AKOS006370225 \| AS-55700 \| Lopac0_000575 \| 5-chloro-1,3-dihydro-2,1-benzoxaborol-1-ol \| DTX
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	AN-2718 is an inhibitor of fungal growth that blocks protein synthesis via the oxaborole tRNA trapping (OBORT) mechanism.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	AN2718 is a benzoxaborole compound that displays broad antifungal effectiveness in vitro. It inhibits leucyl-tRN/A synthetase (LeuRS) from molds and yeasts (IC50s = 2 and 4.2 μM for A. fumigatus and C. albicans LeuRS, respectively), blocking protein synthesis.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organohalogen compounds
  - Class Aryl halides
    - Subclass Aryl chlorides

Kingdom	Organic compounds
Superclass	Organohalogen compounds
Class	Aryl halides
Subclass	Aryl chlorides
Intermediate Tree Nodes	Not available
Direct Parent	Aryl chlorides
Alternative Parents	Benzenoids Oxaborole derivatives Boronic acid esters Oxacyclic compounds Organic metalloid salts Organooxygen compounds Organometalloid compounds Organochlorides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Benzenoid - Aryl chloride - 1,2-oxaborole derivative - Boronic acid ester - Boronic acid derivative - Oxacycle - Organic metalloid salt - Organoheterocyclic compound - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Organochloride - Organic metalloid moeity - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as aryl chlorides. These are organic compounds containing the acyl chloride functional group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

HEK293 (82097 Activities)

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Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

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Trichophyton benhamiae (1686 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Staphylococcus aureus (210822 Activities)

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Acinetobacter baumannii (41033 Activities)

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Escherichia coli (133304 Activities)

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Aspergillus fumigatus (16427 Activities)

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Cryptococcus neoformans (21258 Activities)

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Candida albicans (78123 Activities)

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Trichophyton rubrum (3646 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	5-chloro-1-hydroxy-3H-2,1-benzoxaborole
INCHI	InChI=1S/C7H6BClO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2
InChIKey	HMAFTPZYFJFEHK-UHFFFAOYSA-N
Smiles	B1(C2=C(CO1)C=C(C=C2)Cl)O
Isomeric SMILES	B1(C2=C(CO1)C=C(C=C2)Cl)O
Molecular Weight	168.39
Reaxy-Rn	10657792
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=10657792&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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12 results found

Lot Number	Certificate Type	Date	Item
B2426659	Certificate of Analysis	Jan 18, 2024	A413006
B2426664	Certificate of Analysis	Jan 18, 2024	A413006
B2426665	Certificate of Analysis	Jan 18, 2024	A413006
B2426667	Certificate of Analysis	Jan 18, 2024	A413006
B2426669	Certificate of Analysis	Jan 18, 2024	A413006
B2426670	Certificate of Analysis	Jan 18, 2024	A413006
B2426674	Certificate of Analysis	Jan 18, 2024	A413006
B2426676	Certificate of Analysis	Jan 18, 2024	A413006
B2426678	Certificate of Analysis	Jan 18, 2024	A413006
B2426679	Certificate of Analysis	Jan 18, 2024	A413006
B2426680	Certificate of Analysis	Jan 18, 2024	A413006
B2426683	Certificate of Analysis	Jan 18, 2024	A413006

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Chemical and Physical Properties

Solubility	Solubility (25°C) In vitro Ethanol: mg/mL
Sensitivity	Moisture sensitive
Molecular Weight	168.390 g/mol
XLogP3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	168.015 Da
Monoisotopic Mass	168.015 Da
Topological Polar Surface Area	29.500 Å²
Heavy Atom Count	11
Formal Charge	0
Complexity	155.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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AN-2718 - 98%, high purity , CAS No.174672-06-1

Basic Description

Taxonomic Classification

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

Show more⌵

Chemical and Physical Properties

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

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