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Almotriptan Malate - 10mM in DMSO, high purity , CAS No.181183-52-8(DMSO), Serotonin 1d (5-HT1d) receptor agonist

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
A408681
Grouped product items
SKU Size
Availability
Price Qty
A408681-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$153.90

5-HT1 Selective Inhibitors | Agonists | Antagonists | Modulators

View related series
Compound libraries (12325)

Basic Description

Synonyms LAS 31416 | N,​N-​dimethyl-​5-​[(1-​pyrrolidinylsulfonyl​)​methyl]​-1H-​indole-​3-​ethanamine,compd. with 2-​hydroxy-butanedioic acid
Specifications & Purity 10mM in DMSO
Biochemical and Physiological Mechanisms Almotriptan Malate (LAS 31416) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.
Storage Temp Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type AGONIST
Mechanism of action Serotonin 1d (5-HT1d) receptor agonist
Product Description

Information

Almotriptan Malate (LAS 31416) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.
In vitro


In vivo


Cell Data

cell lines:PC3 cells

Concentrations:

Incubation Time:

Powder Purity:≥99%

Product Properties

ALogP -1.943
hba_count 4
HBD Count 2
Rotatable Bond 9

Names and Identifiers

Smiles CN(C)CCC1=C[NH]C2=CC=C(C[S](=O)(=O)N3CCCC3)C=C12.OC(CC(O)=O)C(O)=O
Molecular Weight 469.55
Reaxy-Rn 15435698
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=15435698&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility Solubility (25°C) In vitro DMSO: 9 mg/mL (47.81 mM); Ethanol: 3 mg/mL (15.93 mM); Water: Insoluble;
DMSO(mg / mL) Max Solubility 94
DMSO(mM) Max Solubility 200.19
Water(mg / mL) Max Solubility <1

Solution Calculators

Reviews

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