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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170472-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$59.90
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Ab170472-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$288.90
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Ab170472-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$687.90
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Ab170472-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,077.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Abituzumab (anti-ITGAV) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to ITGAV, >95%, high purity, Human IgG2, INHIBITOR of Integrin alpha-V/beta-1 inhibitor |
|---|---|
| Synonyms | Abituzumab | antigen identified by monoclonal antibody L230 antibody | CD 51 antibody | CD51 antibody | DKFZp686A08142 antibody | Integrin alpha five antibody | integrin alpha V beta 3 antibody | Integrin alpha-5 antibody | integrin alpha-V antibody | Int |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | ITGAV |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Integrin alpha-V/beta-1 inhibitor |
| Product Description |
Abituzumab (anti-ITGAV) is a recombinant monoclonal antibody to ITGAV. Abituzumab effectively reduces the phosphorylation of FAK, Akt and ERK. Abituzumab can be used in cancer research, particularly in prostate cancer. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG2 |
| Light Chain Type | kappa |
| SDS-PAGE | 27.2 kDa (Light Chain) & 52.6 kDa (Heavy Chain), under reducing conditions; 175.0 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1105038-73-0 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Abituzumab (anti-ITGAV) (Ab170472) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling ITGAV (red) with Abituzumab (anti-ITGAV) (Ab170472). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Abituzumab (anti-ITGAV) (Ab170472) - SEC
The purity of Abituzumab (anti-ITGAV) (Ab170472) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Sep 06, 2023 | Ab170472 | |
| Certificate of Analysis | Sep 06, 2023 | Ab170472 |
Starting at $89.90
| 1. Xiuquan Jia, Jiping Ma, Min Wang, Zhongtian Du, Fang Lu, Feng Wang, Jie Xu. (2014) Promoted role of Cu(NO3)2 on aerobic oxidation of 5-hydroxymethylfurfural to 2,5-diformylfuran over VOSO4. APPLIED CATALYSIS A-GENERAL, 482 (231). |