Skip to the beginning of the images gallery

4'-Fluoro-2'-hydroxyacetophenone - 98%, high purity , CAS No.1481-27-2

COA

Grade & Purity:

≥98%

Cas Number: 1481-27-2
Molecular Weight: 154.14
Beilstein Registry Number: 2249799
MDL number: MFCD00143203
PubChem CID: 2737326
PubChem SID: 488192881

In stock

Item Number

F123259

Grouped product items
SKU	Size	Availability	Price
F123259-1g	1g	3	$13.90
F123259-5g	5g	3	$50.90
F123259-10g	10g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$90.90
F123259-25g	25g	5	$175.90
F123259-100g	100g	3	$632.90
F123259-500g	500g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,847.90

View related series

Carbonyl compound (2335) Non heterocyclic fluorine-containing block (1408)

Basic Description

Synonyms	4'-fluoro-2'hydroxyacetophenone \| 4'-Fluoro-2'-hydroxyacetophenone \| 4-Fluoro-2-hydroxyacetophenone \| 4'-Fluoro-2'-hydroxyacetophenone, 98% \| (2-hydroxy-4-fluoro phenyl)-1-ethanone \| 2'-Hydroxy-4'-fluorophenyl methyl ketone \| 4'-Flouro-2'-hydroxyacetophen
Specifications & Purity	≥98%
Shipped In	Normal
Product Description	Used recently in the preparation of medicinally active benzo[b]furans and thiophenes. application： 4′-Fluoro-2′-hydroxyacetophenone may be used in the preparation of series of 4′-fluoro-2′-hydroxychalcones, via aldol condensation with substituted aldehydes followed by cyclization with hydrazine hydrate.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic oxygen compounds
  - Class Organooxygen compounds
    - Subclass Carbonyl compounds
      - Level5 Ketones
        Level6 Aryl ketones
        Level7 Phenylketones
        Level8 Alkyl-phenylketones

Kingdom	Organic compounds
Superclass	Organic oxygen compounds
Class	Organooxygen compounds
Subclass	Carbonyl compounds
Intermediate Tree Nodes	Ketones - Aryl ketones - Phenylketones
Direct Parent	Alkyl-phenylketones
Alternative Parents	Acetophenones M-fluorophenols Benzoyl derivatives Aryl alkyl ketones Fluorobenzenes 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Aryl fluorides Vinylogous acids Organofluorides Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Alkyl-phenylketone - Acetophenone - Aryl alkyl ketone - Benzoyl - 3-fluorophenol - 3-halophenol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Halobenzene - Fluorobenzene - Aryl fluoride - Aryl halide - Benzenoid - Monocyclic benzene moiety - Vinylogous acid - Organofluoride - Organic oxide - Hydrocarbon derivative - Organohalogen compound - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	488192881
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488192881
IUPAC Name	1-(4-fluoro-2-hydroxyphenyl)ethanone
INCHI	InChI=1S/C8H7FO2/c1-5(10)7-3-2-6(9)4-8(7)11/h2-4,11H,1H3
InChIKey	HLTBTUXAMVOKIH-UHFFFAOYSA-N
Smiles	CC(=O)C1=C(C=C(C=C1)F)O
Isomeric SMILES	CC(=O)C1=C(C=C(C=C1)F)O
WGK Germany	3
Molecular Weight	154.14
Beilstein	2249799
Reaxy-Rn	2249799
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2249799&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Date	Item
F1615161	Certificate of Analysis	Feb 21, 2024	F123259
F2209182	Certificate of Analysis	Mar 10, 2022	F123259
F2209181	Certificate of Analysis	Mar 10, 2022	F123259
F2209183	Certificate of Analysis	Mar 10, 2022	F123259
G2314095	Certificate of Analysis	Mar 10, 2022	F123259
L2419319	Certificate of Analysis	Mar 10, 2022	F123259
B2219152	Certificate of Analysis	Feb 23, 2022	F123259

Chemical and Physical Properties

Flash Point(°F)	210.2 °F
Flash Point(°C)	98°(208°F)
Boil Point(°C)	65°C/2mm
Melt Point(°C)	29-34°C
Molecular Weight	154.140 g/mol
XLogP3	2.100
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	154.043 Da
Monoisotopic Mass	154.043 Da
Topological Polar Surface Area	37.300 Å²
Heavy Atom Count	11
Formal Charge	0
Complexity	158.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions, always use the batch-specific molecular weight of the product found on the vial label and the Certificate of Analysis (available online).

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator enables you to quickly determine the volume of a reagent needed to reconstitute your vial. Just enter the mass of the reagent and the target concentration, and the calculator will do the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration