2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with K i s of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS , respectively.
Storage Temp
Desiccated,Store at -80°C
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Dry ice packs + Cold packs
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Product Description
2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with K i s of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS , respectively 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage .
In Vitro
Application of low concentrations of 2-Iminobiotin (2-IB; 10 ng/mL and 30 ng/mL) superimposed on hypothermia abrogates the hypoxia-induced lactate dehydrogenase (LDH) increase, resulting in LDH levels that were not different from the normoxia control. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:NO synthases
Names and Identifiers
Smiles
C1C2C(C(S1)CCCCC(=O)O)N=C(N2)N.Br
Molecular Weight
324.24
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