Basic Description

Synonyms	HEMA \| 2-Hydroxyethyl 2-methylacrylate # \| EN300-98188 \| InChI=1/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H \| beta-Hydroxyethyl methacrylate \| Methacrylic acid, 2-hydroxyethyl ester \| 1,2-Ethanediol mono(2-methylpropenoate) \| 2-Hydroxyethyl methacrylate (H
Specifications & Purity	≥96%, contains 251 ppm MEHQ as stabilizer
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	2-Hydroxyethyl methacrylate (HEMA) was the first monomer to be used to synthesize hydrogels for biomedical applications.The water swelling properties of HEMA are enhanced by copolymerization with more hydrophilic monomers.HEMA finds wide applications for drug delivery. HEMA is used in the synthesis of biologically functional poly (2-hydroxyethyl methacrylate) (PHEMA) coplymers.It is also used to prepare light responsive membranes of PHEMA,HEMA/ acrylamide based specific drug release hydrogel,and water soluble HEMA/methacrylic acid hydrogel for drug delivery.Effects of HEMA on the migration of dental pulp stem cells (in vitro) may be studied.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Carboxylic acids and derivatives
    - Subclass Carboxylic acid derivatives
      - Level5 Carboxylic acid esters
        Level6 Alpha,beta-unsaturated carboxylic esters
        Level7 Enoate esters

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Subclass	Carboxylic acid derivatives
Intermediate Tree Nodes	Carboxylic acid esters - Alpha,beta-unsaturated carboxylic esters
Direct Parent	Enoate esters
Alternative Parents	Monocarboxylic acids and derivatives Primary alcohols Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic acyclic compounds
Substituents	Enoate ester - Monocarboxylic acid or derivatives - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as enoate esters. These are an alpha,beta-unsaturated carboxylic ester of general formula R1C(R2)=C(R3)C(=O)OR4 (R4= organyl compound) in which the ester C=O function is conjugated to a C=C double bond at the alpha,beta position.
External Descriptors	enoate ester
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	2-hydroxyethyl 2-methylprop-2-enoate
INCHI	InChI=1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3
InChIKey	WOBHKFSMXKNTIM-UHFFFAOYSA-N
Smiles	CC(=C)C(=O)OCCO
Isomeric SMILES	CC(=C)C(=O)OCCO
WGK Germany	NWG
RTECS	OZ4725000
Molecular Weight	130.14
Beilstein	1071580
Reaxy-Rn	1071583
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1071583&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

68 results found

Lot Number	Certificate Type	Date	Item
F2517171	Certificate of Analysis	Jun 20, 2025	H103044
F2517160	Certificate of Analysis	Jun 20, 2025	H103044
F2517162	Certificate of Analysis	Jun 20, 2025	H103044
F2517169	Certificate of Analysis	Jun 20, 2025	H103044
D2529049	Certificate of Analysis	May 05, 2025	H103044
D2529047	Certificate of Analysis	May 05, 2025	H103044
D2529053	Certificate of Analysis	May 05, 2025	H103044
B2519239	Certificate of Analysis	Feb 22, 2025	H103044
B2519238	Certificate of Analysis	Feb 22, 2025	H103044
B2519237	Certificate of Analysis	Feb 22, 2025	H103044
B2519236	Certificate of Analysis	Feb 22, 2025	H103044
A2517150	Certificate of Analysis	Jan 20, 2025	H103044
A2517108	Certificate of Analysis	Jan 20, 2025	H103044
A2517109	Certificate of Analysis	Jan 20, 2025	H103044
L2420315	Certificate of Analysis	Dec 26, 2024	H103044
L2420316	Certificate of Analysis	Dec 26, 2024	H103044
L2420295	Certificate of Analysis	Dec 26, 2024	H103044
L2420296	Certificate of Analysis	Dec 26, 2024	H103044
J2422728	Certificate of Analysis	Oct 29, 2024	H103044
J2422698	Certificate of Analysis	Oct 29, 2024	H103044
J2422703	Certificate of Analysis	Oct 29, 2024	H103044
J2422729	Certificate of Analysis	Oct 29, 2024	H103044
I2407128	Certificate of Analysis	Sep 10, 2024	H103044
I2407133	Certificate of Analysis	Sep 10, 2024	H103044
I2407149	Certificate of Analysis	Sep 10, 2024	H103044
I2407150	Certificate of Analysis	Sep 10, 2024	H103044
H2406145	Certificate of Analysis	Aug 08, 2024	H103044
H2406146	Certificate of Analysis	Aug 08, 2024	H103044
H2406143	Certificate of Analysis	Aug 08, 2024	H103044
H2406144	Certificate of Analysis	Aug 08, 2024	H103044
E2423501	Certificate of Analysis	May 29, 2024	H103044
I2402504	Certificate of Analysis	May 27, 2024	H103044
E2423500	Certificate of Analysis	May 27, 2024	H103044
E2423499	Certificate of Analysis	May 27, 2024	H103044
E2406138	Certificate of Analysis	May 15, 2024	H103044
E2406094	Certificate of Analysis	May 14, 2024	H103044
E2406120	Certificate of Analysis	May 14, 2024	H103044
A2425035	Certificate of Analysis	Feb 01, 2024	H103044
A2425036	Certificate of Analysis	Jan 31, 2024	H103044
A2425038	Certificate of Analysis	Jan 31, 2024	H103044
K2323266	Certificate of Analysis	Nov 24, 2023	H103044
J2323700	Certificate of Analysis	Oct 25, 2023	H103044
G2216348	Certificate of Analysis	Aug 14, 2023	H103044
G2216346	Certificate of Analysis	Aug 14, 2023	H103044
G2311604	Certificate of Analysis	Jul 13, 2023	H103044
G23111352	Certificate of Analysis	Jul 13, 2023	H103044
G2311601	Certificate of Analysis	Jul 13, 2023	H103044
G2311607	Certificate of Analysis	Jul 13, 2023	H103044
C23081214	Certificate of Analysis	Mar 15, 2023	H103044
C23081223	Certificate of Analysis	Mar 15, 2023	H103044
C23081206	Certificate of Analysis	Mar 14, 2023	H103044
C23081211	Certificate of Analysis	Mar 13, 2023	H103044
L2101443	Certificate of Analysis	Jan 12, 2023	H103044
L2101447	Certificate of Analysis	Jan 12, 2023	H103044
E2331160	Certificate of Analysis	Nov 25, 2022	H103044
K2222038	Certificate of Analysis	Nov 25, 2022	H103044
K2222037	Certificate of Analysis	Nov 24, 2022	H103044
K2222039	Certificate of Analysis	Nov 24, 2022	H103044
H2222053	Certificate of Analysis	Aug 23, 2022	H103044
H2222052	Certificate of Analysis	Aug 23, 2022	H103044
G2216345	Certificate of Analysis	Jul 19, 2022	H103044
F2102306	Certificate of Analysis	Jul 14, 2022	H103044
F2102311	Certificate of Analysis	Jul 14, 2022	H103044
D2108256	Certificate of Analysis	Jun 08, 2022	H103044
E2217121	Certificate of Analysis	May 19, 2022	H103044
E2217119	Certificate of Analysis	May 19, 2022	H103044
L2101453	Certificate of Analysis	Dec 09, 2021	H103044
G2216347	Certificate of Analysis	Dec 09, 2021	H103044

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Chemical and Physical Properties

Sensitivity	Light Sensitive
Refractive Index	1.451-1.453
Flash Point(°F)	222.8 °F
Flash Point(°C)	101℃
Boil Point(°C)	85°C/5mmHg
Melt Point(°C)	-12℃
Molecular Weight	130.139 g/mol
XLogP3	0.500
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	130.063 Da
Monoisotopic Mass	130.063 Da
Topological Polar Surface Area	46.500 Å²
Heavy Atom Count	9
Formal Charge	0
Complexity	117.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

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SKU	Size	Availability	Price
H103044-25g	25g	2	$9.90
H103044-100g	100g	3	$25.90
H103044-500g	500g	2	$79.90

2-Hydroxyethyl methacrylate - 96%,contains 250 ppm MEHQ as stabilizer, high purity , CAS No.868-77-9