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2′-Deoxycytidine 5′-monophosphate - 99%, high purity , CAS No.1032-65-1

    Grade & Purity:
  • ≥99%
In stock
Item Number
D119528
Grouped product items
SKU Size
Availability
Price Qty
D119528-250mg
250mg
2
$30.90
D119528-1g
1g
2
$93.90
D119528-5g
5g
3
$422.90

Uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase substrate.

Basic Description

Synonyms deoxycytidine dihydrogen phosphate | Deoxycytidylate | 1njc | deoxycytidylic acid | 2'-Deoxycytidine 5'-monophosphate, Sigma Grade, >=95.0% | Cytidine 5'-(dihydrogen phosphate) | SCHEMBL48317 | deoxycytidine monophosphate | AS-64039 | dCMP | 1nje | 2'-DEO
Specifications & Purity ≥99%
Biochemical and Physiological Mechanisms Nucleoside monophosphate used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation to dCTP supports DNA biosynthesis.
Storage Temp Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

2′-Deoxycytidine 5′-monophosphate (dCMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation to dCTP supports DNA biosynthesis.

It consists of a 2′-deoxy-β-D-ribofuranose, linked through an N-β-D-glycosidic linkage to a heterocycle nitrogen cytosine.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Nucleosides, nucleotides, and analogues
Class Pyrimidine nucleotides
Subclass Pyrimidine deoxyribonucleotides
Intermediate Tree Nodes Pyrimidine deoxyribonucleoside monophosphates
Direct Parent Pyrimidine 2'-deoxyribonucleoside monophosphates
Alternative Parents Pyrimidones  Monoalkyl phosphates  Aminopyrimidines and derivatives  Imidolactams  Hydropyrimidines  Tetrahydrofurans  Heteroaromatic compounds  Secondary alcohols  Oxacyclic compounds  Azacyclic compounds  Primary amines  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Pyrimidine 2'-deoxyribonucleoside monophosphate - Aminopyrimidine - Pyrimidone - Monoalkyl phosphate - Hydropyrimidine - Organic phosphoric acid derivative - Phosphoric acid ester - Pyrimidine - Imidolactam - Alkyl phosphate - Heteroaromatic compound - Tetrahydrofuran - Secondary alcohol - Oxacycle - Azacycle - Organoheterocyclic compound - Hydrocarbon derivative - Primary amine - Organic oxide - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Alcohol - Amine - Organic nitrogen compound - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleoside monophosphates. These are pyrimidine nucleotides with a monophosphate group linked to the ribose moiety lacking a hydroxyl group at position 2.
External Descriptors Deoxyribonucleotides

Associated Targets(Human)

CMPK1 Tchem UMP-CMP kinase (152 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Deoxycytidylate deaminase (6 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504752510
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504752510
IUPAC Name [(2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate
INCHI InChI=1S/C9H14N3O7P/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(19-8)4-18-20(15,16)17/h1-2,5-6,8,13H,3-4H2,(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1
InChIKey NCMVOABPESMRCP-SHYZEUOFSA-N
Smiles C1C(C(OC1N2C=CC(=NC2=O)N)COP(=O)(O)O)O
Isomeric SMILES C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)COP(=O)(O)O)O
WGK Germany 3
Molecular Weight 307.2
Beilstein 41062
Reaxy-Rn 14609574
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14609574&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number Certificate Type Date Item
G2501569 Certificate of Analysis Jul 13, 2024 D119528
G2205095 Certificate of Analysis Jun 04, 2022 D119528
G2305155 Certificate of Analysis Jan 19, 2022 D119528
C2222315 Certificate of Analysis Jan 19, 2022 D119528
C2222316 Certificate of Analysis Jan 19, 2022 D119528
C2222320 Certificate of Analysis Jan 19, 2022 D119528

Chemical and Physical Properties

Solubility Soluble in water.
Sensitivity Moisture sensitive;Heat sensitive
Specific Rotation[α] 37° (C=1,H2O)
Melt Point(°C) 161 °C(dec.)
Molecular Weight 307.200 g/mol
XLogP3 -3.400
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 4
Exact Mass 307.057 Da
Monoisotopic Mass 307.057 Da
Topological Polar Surface Area 155.000 Ų
Heavy Atom Count 20
Formal Charge 0
Complexity 502.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 3
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

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