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Z-Gly-Pro

    级别和纯度:
  • ≥99%(TLC)
有货

库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Z465709-5g
5g 期货 Stock Image

基本描述

别名 Z-甘氨酸-Pro
英文别名 L-Proline, N-[(phenylmethoxy)carbonyl]glycyl- | Z-Glycyl-L-proline | Q27108580 | (S)-1-(2-(((Benzyloxy)carbonyl)amino)acetyl)pyrrolidine-2-carboxylic acid | SCHEMBL2228388 | Z-Gly-Pro | MFCD00037341 | DTXSID501292362 | L-Proline,N-[(phenylmethoxy)carbonyl
规格或纯度 ≥99.0% (TLC)
英文名称 Z-Gly-Pro
纯度 ≥99%(TLC)

名称和识别符

IIUPAC Name (2S)-1-[2-(phenylmethoxycarbonylamino)acetyl]pyrrolidine-2-carboxylic acid
INCHI 1S/C15H18N2O5/c18-13(17-8-4-7-12(17)14(19)20)9-16-15(21)22-10-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10H2,(H,16,21)(H,19,20)/t12-/m0/s1
Smiles C1CC(N(C1)C(=O)CNC(=O)OCC2=CC=CC=C2)C(=O)O
Isomeric SMILES C1C[C@H](N(C1)C(=O)CNC(=O)OCC2=CC=CC=C2)C(=O)O
PubChem CID 439540
分子量 306.31
Beilstein号 94536

化学和物理性质

比旋光度 [α]20/D −70±2°, c = 2% in ethanol
熔点 155-158 °C
分子量 306.310 g/mol
XLogP3 0.700
氢键供体数Hydrogen Bond Donor Count 2
氢键受体数Hydrogen Bond Acceptor Count 5
可旋转键计数Rotatable Bond Count 6
精确质量Exact Mass 306.122 Da
单同位素质量Monoisotopic Mass 306.122 Da
拓扑极表面积Topological Polar Surface Area 95.900 Ų
重原子数Heavy Atom Count 22
形式电荷Formal Charge 0
复杂度Complexity 420.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 1
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。

WGK Germany 3
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

引用文献

1. I Nagaoka,T Yamashita.  (1985-10-30)  Possible involvement of aminopeptidase, an ecto-enzyme, in the inactivation of bradykinin by intact neutrophils..  Biochimica et biophysica acta,  847  ((1)): (67-76).  [PMID:3902095]
2. Y Bergqvist,J al Kabbani,C Pettersson,N H Huynh.  (1993-10-29)  Enantioselective high-performance liquid chromatographic determination of (SR)- and (RS)-mefloquine in plasma using N-benzyloxycarbonyl-glycyl-L-proline as chiral counter ion..  Journal of chromatography,  620  ((2)): (217-224).  [PMID:8300789]
3. V Fülöp,Z Szeltner,V Renner,L Polgár.  (2000-10-14)  Structures of prolyl oligopeptidase substrate/inhibitor complexes. Use of inhibitor binding for titration of the catalytic histidine residue..  The Journal of biological chemistry,  276  ((2)): (1262-1266).  [PMID:11031266]
4. A Karlsson,C Pettersson,S Björkman.  (1989-09-29)  Determination of (R)- and (S)-propranolol in plasma by high-performance liquid chromatography using N-benzoxycarbonylglycyl-L-proline as chiral selector in the mobile phase..  Journal of chromatography,  494  (157-171).  [PMID:2584313]
5. N H Huynh,A Karlsson,C Pettersson.  (1995-06-30)  Enantiomeric separation of basic drugs using N-benzyloxycarbonylglyclyl-L-proline as counter ion in methanol..  Journal of chromatography. A,  705  ((2)): (275-287).  [PMID:7640770]
6. Ylva Hedeland,Mikael Hedeland,Ulf Bondesson,Curt Pettersson.  (2003-02-05)  Chiral separation of amines with N-benzoxycarbonylglycyl-L-proline as selector in non-aqueous capillary electrophoresis using methanol and 1,2-dichloroethane in the background electrolyte..  Journal of chromatography. A,  984  ((2)): (261-271).  [PMID:12564698]

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