| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Y1493101-1ml |
1ml |
期货  |
|
| 规格或纯度 | Moligand™, 10 mM in DMSO |
|---|---|
| 英文名称 | YM-53601 |
| 储存温度 | 干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
YM-53601, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo. YM-53601 inhibits squalene synthase derived from human hepatoma cells with an IC 50 of 79 nM. Lipid-lowering agent. YM-53601 is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 ( FDFT1 ) enzyme activity and abrogates HCV propagation. |
| IC50 | Squalene synthase activity: IC₅₀= 79 nM (human Hep-G2 cells); Squalene synthase activity: IC₅₀= 90 nM (rat hepatIC₅₀IC₅₀somes) |
|---|
| Isomeric SMILES | C1CN2CCC1C(=C(COC3=CC4=C(C=C3)C5=CC=CC=C5N4)F)C2.Cl |
|---|---|
| PubChem CID | 9907532 |
| 分子量 | 372.86 |
| 折光率 | n20D~1.69 (Predicted) |
|---|---|
| 熔点 | 236.5-237.2° C |
| WGK Germany | 3 |
|---|
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