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| 描述 | 丝氨酸/苏氨酸蛋白激酶 PLK4 |
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基因和蛋白信息
| 基因ID | 10733 |
|---|---|
| Uniprot Accession IDs | O00444 B2RAL0 B7Z837 B7Z8G7 Q8IYF0 Q96Q95 Q9UD84 Q9UDE2 |
| Ensembl ID | ENSG00000142731 |
| 原子符号 | SAK STK18 SAK STK18 MCCRP2 |
| Chromosome | 4 |
| 家族 | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. |
| 序列 |
MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRVIQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERYSPTDNNANIFNFFKEKTSSSSGSFERPDNNQALSNHLCPGKTPFPFADPTPQTETVQQWFGNLQINAHLRKTTEYDSISPNRDFQGHPDLQKDTSKNAWTDTKVKKNSDASDNAHSVKQQNTMKYMTALHSKPEIIQQECVFGSDPLSEQSKTRGMEPPWGYQNRTLRSITSPLVAHRLKPIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLADRPPSPTDNISRYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICLALESIISEEERKTRSAPFFPIIIGRKPGSTSSPKALSPPPSVDSNYPTRERASFNRMVMHSAASPTQAPILNPSMVTNEGLGLTTTASGTDISSNSLKDCLPKSAQLLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLSSILLMFSNPTPNFH
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同源基因和蛋白信息
| 同源种属 | 基因编号（Gene ID） | 基因名称（Gene Symbol) | 蛋白名称 | 种属编号（Tax ID) | 其它基因编号（Gene ID） | 来源 |
|---|---|---|---|---|---|---|
| Chimp | 461480 | PLK4 | polo like kinase 4 | 9598 | VGNC:7051 | OMA, EggNOG |
| Macaque | 710233 | PLK4 | polo like kinase 4 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 20873 | Plk4 | polo like kinase 4 | 10090 | MGI:101783 | Inparanoid, OMA, EggNOG |
| Rat | 310344 | Plk4 | polo-like kinase 4 | 10116 | RGD:1305390 | Inparanoid, OMA, EggNOG |
| Dog | 476087 | PLK4 | polo like kinase 4 | 9615 | VGNC:44698 | Inparanoid, OMA, EggNOG |
| Horse | 100063593 | PLK4 | polo like kinase 4 | 9796 | VGNC:21582 | Inparanoid, OMA, EggNOG |
| Cow | 514405 | PLK4 | polo like kinase 4 | 9913 | VGNC:33036 | Inparanoid, OMA, EggNOG |
| Opossum | 100010836 | PLK4 | polo like kinase 4 | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 422497 | PLK4 | polo like kinase 4 | 9031 | CGNC:51756 | OMA, EggNOG |
| Anole lizard | 100557501 | plk4 | polo like kinase 4 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100038180 | plk4 | polo like kinase 4 | 8364 | XB-GENE-493608 | Inparanoid, OMA, EggNOG |
| Zebrafish | 368390 | plk4 | polo-like kinase 4 (Drosophila) | 7955 | ZDB-GENE-030619-14 | Inparanoid, OMA, EggNOG |
| Fruitfly | 40384 | SAK | Sak kinase | 7227 | FBgn0026371 | Inparanoid, OMA, EggNOG |
相关重组蛋白
| 蛋白名称 | 规格与纯度 | 表达系统 | 蛋白标签 | 是否现货 | 查看详情 |
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相关抗体
| 名称 | 规格与纯度 | 种属反应性 | 应用 | 是否现货 | 查看详情 |
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Associated Approved Drugs
相关活性配体
相关疾病
| 疾病英文名称 | 疾病中文名称 | 疾病类型 | Mondoid | Direct Associated Targets |
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