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| 描述 | 非受体酪氨酸蛋白激酶 TYK2 |
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基因和蛋白信息
| 基因ID | 7297 |
|---|---|
| Uniprot Accession IDs | P29597 Q6QB10 Q96CH0 |
| Ensembl ID | ENSG00000105397 |
| 原子符号 | JTK1 IMD35 |
| Chromosome | 19 |
| 家族 | Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. |
| 序列 |
MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC
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同源基因和蛋白信息
| 同源种属 | 基因编号（Gene ID） | 基因名称（Gene Symbol) | 蛋白名称 | 种属编号（Tax ID) | 其它基因编号（Gene ID） | 来源 |
|---|---|---|---|---|---|---|
| Chimp | 455703 | TYK2 | tyrosine kinase 2 | 9598 | VGNC:2210 | OMA, EggNOG |
| Macaque | 574130 | TYK2 | tyrosine kinase 2 | 9544 | OMA, EggNOG | |
| Mouse | 54721 | Tyk2 | tyrosine kinase 2 | 10090 | MGI:1929470 | Inparanoid, OMA, EggNOG |
| Rat | 100361294 | Tyk2 | tyrosine kinase 2 | 10116 | RGD:2320469 | Inparanoid, OMA, EggNOG |
| Dog | 476714 | TYK2 | tyrosine kinase 2 | 9615 | VGNC:48024 | Inparanoid, OMA, EggNOG |
| Horse | TYK2 | tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440] | 9796 | OMA, EggNOG | ||
| Cow | 512484 | TYK2 | tyrosine kinase 2 | 9913 | VGNC:36548 | Inparanoid, OMA, EggNOG |
| Pig | 397363 | TYK2 | tyrosine kinase 2 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100012931 | TYK2 | tyrosine kinase 2 | 13616 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100566727 | tyk2 | tyrosine kinase 2 | 28377 | Inparanoid, OMA | |
| Xenopus | 100489432 | tyk2 | tyrosine kinase 2 | 8364 | XB-GENE-993652 | Inparanoid, OMA |
| Zebrafish | 100536675 | tyk2 | tyrosine kinase 2 | 7955 | ZDB-GENE-071116-4 | Inparanoid, OMA |
相关重组蛋白
| 蛋白名称 | 规格与纯度 | 表达系统 | 蛋白标签 | 是否现货 | 查看详情 |
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相关抗体
| 名称 | 规格与纯度 | 种属反应性 | 应用 | 是否现货 | 查看详情 |
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Associated Approved Drugs
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相关疾病
| 疾病英文名称 | 疾病中文名称 | 疾病类型 | Mondoid | Direct Associated Targets |
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