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| 描述 | 酪氨酸蛋白激酶JAK2 |
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基因和蛋白信息
| 基因ID | 3717 |
|---|---|
| Uniprot Accession IDs | O60674 O14636 O75297 |
| Ensembl ID | ENSG00000096968 |
| 原子符号 | JTK10 THCYT3 |
| Chromosome | 9 |
| 家族 | Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. |
| 序列 |
MGMACLTMTEMEGTSTSSIYQNGDISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSNRAYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLGMAVLDMMRIAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSRGKHKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
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同源基因和蛋白信息
| 同源种属 | 基因编号（Gene ID） | 基因名称（Gene Symbol) | 蛋白名称 | 种属编号（Tax ID) | 其它基因编号（Gene ID） | 来源 |
|---|---|---|---|---|---|---|
| Chimp | 464979 | JAK2 | Janus kinase 2 | 9598 | VGNC:4770 | OMA, EggNOG |
| Macaque | 694184 | JAK2 | Janus kinase 2 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 16452 | Jak2 | Janus kinase 2 | 10090 | MGI:96629 | Inparanoid, OMA, EggNOG |
| Rat | 24514 | Jak2 | Janus kinase 2 | 10116 | RGD:2939 | Inparanoid, OMA |
| Dog | 484185 | JAK2 | Janus kinase 2 | 9615 | VGNC:42176 | Inparanoid, OMA |
| Horse | 100051487 | JAK2 | Janus kinase 2 | 9796 | VGNC:19213 | Inparanoid, OMA |
| Cow | 525246 | JAK2 | Janus kinase 2 | 9913 | VGNC:30365 | Inparanoid, OMA |
| Pig | 397201 | JAK2 | Janus kinase 2 | 9823 | Inparanoid, OMA | |
| Opossum | 100017930 | JAK2 | Janus kinase 2 | 13616 | Inparanoid, OMA | |
| Platypus | 100074305 | JAK2 | Janus kinase 2 | 9258 | Inparanoid, OMA | |
| Chicken | 374199 | JAK2 | Janus kinase 2 | 9031 | CGNC:11173 | Inparanoid, OMA |
| Anole lizard | 100552375 | jak2 | Janus kinase 2 | 28377 | Inparanoid, OMA | |
| Xenopus | 100036599 | jak2 | Janus kinase 2 (a protein tyrosine kinase) | 8364 | XB-GENE-483712 | Inparanoid, OMA |
| Zebrafish | 30298 | jak2b | Janus kinase 2b | 7955 | ZDB-GENE-980526-123 | Inparanoid, OMA |
相关重组蛋白
| 蛋白名称 | 规格与纯度 | 表达系统 | 蛋白标签 | 是否现货 | 查看详情 |
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相关抗体
| 名称 | 规格与纯度 | 种属反应性 | 应用 | 是否现货 | 查看详情 |
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Associated Approved Drugs
相关活性配体
相关疾病
| 疾病英文名称 | 疾病中文名称 | 疾病类型 | Mondoid | Direct Associated Targets |
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