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| 描述 | 酪氨酸蛋白激酶JAK1 |
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基因和蛋白信息
| 基因ID | 3716 |
|---|---|
| Uniprot Accession IDs | P23458 Q59GQ2 Q9UD26 |
| Ensembl ID | ENSG00000162434 |
| 原子符号 | JAK1A JAK1B JTK3 JAK1A JAK1B |
| Chromosome | 1 |
| 家族 | Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. |
| 序列 |
MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEELCIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTNDNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQDGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMNWFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIREEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFMLKRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSGTLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK
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同源基因和蛋白信息
| 同源种属 | 基因编号（Gene ID） | 基因名称（Gene Symbol) | 蛋白名称 | 种属编号（Tax ID) | 其它基因编号（Gene ID） | 来源 |
|---|---|---|---|---|---|---|
| Chimp | 743373 | JAK1 | Janus kinase 1 | 9598 | VGNC:1281 | OMA, EggNOG |
| Macaque | 677689 | JAK1 | Janus kinase 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 16451 | Jak1 | Janus kinase 1 | 10090 | MGI:96628 | Inparanoid, OMA, EggNOG |
| Rat | 84598 | Jak1 | Janus kinase 1 | 10116 | RGD:69056 | Inparanoid, OMA, EggNOG |
| Dog | 442952 | JAK1 | Janus kinase 1 | 9615 | VGNC:42175 | Inparanoid, OMA, EggNOG |
| Horse | 100054008 | JAK1 | Janus kinase 1 | 9796 | VGNC:19212 | Inparanoid, OMA, EggNOG |
| Cow | 537201 | JAK1 | Janus kinase 1 | 9913 | VGNC:30364 | Inparanoid, OMA, EggNOG |
| Chicken | 395681 | JAK1 | Janus kinase 1 | 9031 | CGNC:8381 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100559328 | jak1 | Janus kinase 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100038172 | jak1 | Janus kinase 1 (a protein tyrosine kinase) | 8364 | XB-GENE-483750 | Inparanoid, OMA, EggNOG |
| Zebrafish | 30280 | jak1 | Janus kinase 1 | 7955 | ZDB-GENE-980526-142 | Inparanoid, OMA |
| Fruitfly | 32080 | hop | hopscotch | 7227 | FBgn0004864 | OMA, EggNOG |
相关重组蛋白
| 蛋白名称 | 规格与纯度 | 表达系统 | 蛋白标签 | 是否现货 | 查看详情 |
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相关抗体
| 名称 | 规格与纯度 | 种属反应性 | 应用 | 是否现货 | 查看详情 |
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Associated Approved Drugs
相关活性配体
相关疾病
| 疾病英文名称 | 疾病中文名称 | 疾病类型 | Mondoid | Direct Associated Targets |
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