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| 产品名称 | TPO mouse |
|---|---|
| 规格或纯度 | 无动物源, 重组, ≥98%(SDS-PAGE&HPLC), expressed in E. coli |
| 生化机理 | TPO(血小板生成素)是血小板系血栓形成的关键调节因子。在小鼠和人类中,该基因失活会导致骨髓祖细胞产生的成熟血小板数量显著减少。这种蛋白表达量增加的转基因小鼠会出现骨髓进行性纤维化和骨硬化,肾脏也会出现组织学变化,导致间质增生性肾小球病。 |
| 产品介绍 |
TPO (thrombopoietin) is a hematopoietic cytokine expressed in multiple tissue types. It is predominantly produced by liver and kidney and acts as a ligand for the cell surface receptor c-mpl. TPO (thrombopoietin) is a hematopoietic cytokine expressed in multiple tissue types. It is predominantly produced by liver and kidney and acts as a ligand for the cell surface receptor c-mpl. |
| 物理形态 | 固体 |
|---|---|
| 浓度 | expressed in E. coli |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |