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三甲胺 N-氧化物二水合物

    级别和纯度:
  • 10mM in DMSO
  • CAS编号: 62637-93-8
  • 分子式: C3H9NO·2H2O
  • 分子量: 111.14
  • PubChem编号: 198430
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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
T425177-1ml
1ml 现货 Stock Image

基本描述

别名 TMANO 二水合物 | TMAO 二水合物
英文别名 62637-93-8 | Trimethylamine N-oxide dihydrate | trimethylamine oxide dihydrate | Trimethylamine-N-oxide dihydrate | Trimethylamine oxide, dihydrate | N,N-Dimethylmethanamine oxide, dihydrate | MFCD00149077 | N,N-dimethylmethanamine oxide;dihydrate | C73WZ0186W | Trimethyla
规格或纯度 10mM in DMSO
英文名称 Trimethylamine N-Oxide Dihydrate
储存温度 -80℃储存
运输条件 超低温冰袋运输
产品介绍

Trimethylamine N-oxide (TMAO) is an amphiphilic osmolyte that can counteract the denaturing effects of urea, pressure, and ice and stabilize the proteins.

Trimethylamine N-oxide (TMAO) is an amphiphilic osmolyte that can counteract the denaturing effects of urea, pressure, and ice and stabilize the proteins.
Reactant for: · C-H bond cleavage · Oxidation reactions (oxidant) · Decarbonylating agent for solvent-free reactions Trimethylamine N-oxide dihydrate can react with transition-metal carbonyl cluster compounds and activate CO displacement by converting CO ligands into carbon dioxide.

名称和识别符

IIUPAC Name N,N-dimethylmethanamine oxide;dihydrate
INCHI 1S/C3H9NO.2H2O/c1-4(2,3)5;;/h1-3H3;2*1H2
InChi Key PGFPZGKEDZGJQZ-UHFFFAOYSA-N
Smiles C[N+](C)(C)[O-].O.O
Isomeric SMILES C[N+](C)(C)[O-].O.O
PubChem CID 198430
分子量 111.14

化学和物理性质

敏感性 对湿度敏感
熔点 96-101°C
分子量 111.140 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count 2
氢键受体数Hydrogen Bond Acceptor Count 3
可旋转键计数Rotatable Bond Count 0
精确质量Exact Mass 111.09 Da
单同位素质量Monoisotopic Mass 111.09 Da
拓扑极表面积Topological Polar Surface Area 20.100 Ų
重原子数Heavy Atom Count 7
形式电荷Formal Charge 0
复杂度Complexity 28.400
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 3

安全和危险性(GHS)

象形图 GHS07
信号词 警告
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

预防措施声明

P264: 处理后要彻底洗手。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P321: 特殊处理(请参阅此标签上的...)。

P302+P352: 如皮肤沾染:用水充分清洗。

P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。

P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续:寻求医疗帮助。

P332+P317: 如果出现皮肤刺激:请寻求医疗帮助。

Merck Index 9711

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

此产品的引用文献

引用文献

1. Lu Bai, Jing Dai, Yuxuan Xia, Kaichuan He, Hongmei Xue, Qi Guo, Danyang Tian, Lin Xiao, Xiangjian Zhang, Xu Teng, Yuming Wu, Sheng Jin.  (2022)  Hydrogen Sulfide Ameliorated High Choline-Induced Cardiac Dysfunction by Inhibiting cGAS-STING-NLRP3 Inflammasome Pathway.  Oxidative Medicine and Cellular Longevity,  2022  (1392896).  [PMID:35910846] [10.1155/2022/1392896]
2. Jun Zhang, Jiang-ping Tu, Gao-hui Du, Zi-min Dong, Yi-shan Wu, Ling Chang, Dong Xie, Guo-fa Cai, Xiu-li Wang.  (2013)  Ultra-thin WO3 nanorod embedded polyaniline composite thin film: Synthesis and electrochromic characteristics.  SOLAR ENERGY MATERIALS AND SOLAR CELLS,  114  (31).  [10.1016/j.solmat.2013.02.025]
3. Yuming Huang, Lin Liu, Hang Yang, Huixuan Yi, Xiangyu Li, Linqian Li, Dawei Lu, Qian Liu, Guibin Jiang.  (2024)  Endogenous formation of Fe-bearing particles and their differentiation from exogenous exposure.  Journal of Environmental Sciences,  [10.1016/j.jes.2024.11.008]
4. Xiaoyun Yang, Yi Wang, Yujin Feng, Feng Wang, Lijuan Gao, Yueheng Wang.  (2025)  Trimethylamine oxide promotes myocardial fibrosis through activating JAK2-STAT3 pathway.  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,  750  (151390).  [PMID:39889626] [10.1016/j.bbrc.2025.151390]

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