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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| S650551-1mg |
1mg |
期货 ![]() |
| |
| S650551-5mg |
5mg |
期货 ![]() |
|
| 别名 | 索利托单抗 |
|---|---|
| 英文名称 | Solitomab |
| 生化机理 | 索利妥单抗(AMG 110)是一种双特异性抗 CD3 和抗上皮细胞粘附分子(EpCAM)抗体。Solitomab 可用于原发性子宫癌和卵巢癌的研究。 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
Solitomab (AMG 110) is a bispecific anti-CD3 and anti-epithelial-cell-adhesion-molecule (EpCAM) antibody. Solitomab can be used for the research of primary uterine and ovarian carcinosarcoma cancer. In Vitro Solitomab (1 μg/mL; 4 hours) shows cytotoxicity to EpCAM-positive cell lines and increases the sensibility of EpCAM positive carcinosarcomas (CS) cells to T-cell-cytotoxicity. Solitomab (7 days) increases the expression level of CD25 and HLA-DR protein (T-cell activation markers) on CD8 + and CD4 + T cells. Solitomab (0-2.5 μg/mL; 4 hours) is cytotoxic to ovarian carcinoma cells and the 1 μg/mL dose shows the best tumor killing effects. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Liquid |
| Smiles | [Solitomab] |
|---|