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Solitomab

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
S650551-1mg
1mg 期货 Stock Image
S650551-5mg
5mg 期货 Stock Image

基本描述

别名 索利托单抗
英文名称 Solitomab
生化机理 索利妥单抗(AMG 110)是一种双特异性抗 CD3 和抗上皮细胞粘附分子(EpCAM)抗体。Solitomab 可用于原发性子宫癌和卵巢癌的研究。
储存温度 -20°C储存
运输条件 超低温冰袋运输
产品介绍


Solitomab (AMG 110) is a bispecific anti-CD3 and anti-epithelial-cell-adhesion-molecule (EpCAM) antibody. Solitomab can be used for the research of primary uterine and ovarian carcinosarcoma cancer.

In Vitro

Solitomab (1 μg/mL; 4 hours) shows cytotoxicity to EpCAM-positive cell lines and increases the sensibility of EpCAM positive carcinosarcomas (CS) cells to T-cell-cytotoxicity. Solitomab (7 days) increases the expression level of CD25 and HLA-DR protein (T-cell activation markers) on CD8 + and CD4 + T cells. Solitomab (0-2.5 μg/mL; 4 hours) is cytotoxic to ovarian carcinoma cells and the 1 μg/mL dose shows the best tumor killing effects. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Liquid

名称和识别符

Smiles [Solitomab]

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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