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羧甲基淀粉钠

27篇引用文献 COA COA
低至 ¥239.90
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main product photo

基本描述

规格或纯度 JP, 欧洲药典（Ph.Eur）, NF, EtOH-based
英文名称 Sodium Starch Glycolate
运输条件 常规运输
产品介绍

产品描述：

S494224，淀粉乙醇酸钠，是一种由马铃薯淀粉通过羧甲基化和交联制备的超级分散剂，用于片剂和其他口服固体剂型。其独特的性能和成本效益组合已成为全球公认的、广泛应用于制药行业的产品。

S494224在与水和其他介质接触时表现出强烈的溶胀性能。这种高纯度的赋形剂保留其球形结构以促进良好的流动性，几乎不含氯化钠或乙醇，并且具有高亮度。


优点：

1.良好的流动性和混合性能

2.专业等级

3.强膨胀性能


产品规格与参数：

项目号 pH值 非转基因 药品注册类型 主要应用 包装
S494224-NM-500g 5.5 – 7.5 ✓ A 超级崩解剂，具有快速和高溶胀度，适用于片剂和胶囊制剂。特别是对于水溶性较差的活性物质和pH值较高的片剂基质。 500g
S494224-CLV-500g 5.5 – 7.5 ✓ A 交联次数增加的特殊等级。特别适用于湿法造粒应用。 500g
S494224-PCF-500g 5.5 – 7.5 ✓ A 对于要求极低离子含量的原料药，建议使用最高0.7%NaCl的特殊等级。 500g
S494224-Low pH-500g 5.5 – 7.5 ✓ B 特殊等级，pH值低。符合欧洲药典，NF，JP的B型。 500g
S494224-NM-2.5kg 5.5 – 7.5 ✓ A 超级崩解剂，具有快速和高溶胀度，适用于片剂和胶囊制剂。特别是对于水溶性较差的活性物质和pH值较高的片剂基质。 2.5kg
S494224-CLV-2.5kg 5.5 – 7.5 ✓ A 交联次数增加的特殊等级。特别适用于湿法造粒应用。 2.5kg
S494224-PCF-2.5kg 5.5 – 7.5 ✓ A 对于要求极低离子含量的原料药，建议使用最高0.7%NaCl的特殊等级。 2.5kg
S494224-Low pH-2.5kg 5.5 – 7.5 ✓ B 特殊等级，pH值低。符合欧洲药典，NF，JP的B型。 2.5kg

S494224, sodium starch glycolate, is a superdistintegrant made from potato starch by carboxymethylation and crosslinking for tablets and other oral solid dosage forms. Its unique combination of performance and cost-effectiveness has established as globally recognized and widely used product in the pharmaceutical industry.

S494224  demonstrates strong swelling properties upon contact with water and other media. This highly pure excipient retains its spheroid structure to promote good flow, contain little sodium chloride or ethanol, and have high brightness.


Benefits:

1.Good flowability and mixing properties

2.Specialty grades

3.Strong swelling properties


Product specifications and parameters:

SKU pH Value GMO Free Compendial Type Main Application Pack Size
S494224-NM-500g 5.5 – 7.5 ✓ A Superdisintegrant with a rapid and high degree of swelling for tablet and capsule formulations. Especially for poorly water-soluble actives and tablet matrices with higher pH values. 500g
S494224-CLV-500g 5.5 – 7.5 ✓ A Special grade with increased number of crosslinkings. Especially suited for wet granulation applications. 500g
S494224-PCF-500g 5.5 – 7.5 ✓ A Special grade with max. 0.7 % NaCl recommended for APIs which require a very low ion content. 500g
S494224-Low pH-500g 5.5 – 7.5 ✓ B Special grade with low pH value. Complies with Type B of Ph. Eur, NF, JP. 500g
S494224-NM-2.5kg 5.5 – 7.5 ✓ A Superdisintegrant with a rapid and high degree of swelling for tablet and capsule formulations. Especially for poorly water-soluble actives and tablet matrices with higher pH values. 2.5kg
S494224-CLV-2.5kg 5.5 – 7.5 ✓ A Special grade with increased number of crosslinkings. Especially suited for wet granulation applications. 2.5kg
S494224-PCF-2.5kg 5.5 – 7.5 ✓ A Special grade with max. 0.7 % NaCl recommended for APIs which require a very low ion content. 2.5kg
S494224-Low pH-2.5kg 5.5 – 7.5 ✓ B Special grade with low pH value. Complies with Type B of Ph. Eur, NF, JP. 2.5kg

名称和识别符

PubChem CID 47207535

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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此产品的引用文献

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引用文献

1. Shuo Li, Li Shi, Ting Ye, Biao Huang, Yuan Qin, Yongkang Xie, Xiaoyuan Ren, Xueqin Zhao.  (2023)  Development of Crosslinker-Free Polysaccharide-Lysozyme Microspheres for Treatment Enteric Infection.  Polymers,  15  (5): (1077).  [PMID:36904318] [10.3390/polym15051077]
2. Fanli Shi, Ruilong Li, Wenjing Wang, Xiangyu Yu, Fenxia Zhu, Yiping Huang, Jing Wang, Zhenhai Zhang.  (2023)  Carboxymethyl starch as a solid dispersion carrier to enhance the dissolution and bioavailability of piperine and 18β-glycyrrhetinic acid.  DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY,  [PMID:36803327] [10.1080/03639045.2023.2182120]
3. Yiyan Gao, Zhixin Zhang, Xiuyan Ren, Fei Jia, Guanghui Gao.  (2022)  A hydrogel sensor driven by sodium carboxymethyl starch with synergistic enhancement of toughness and conductivity.  Journal of Materials Chemistry B,  10  (30): (5743-5752).  [PMID:35802130] [10.1039/D2TB00839D]
4. Luhui Wang, Zihao Wei, Changhu Xue.  (2022)  The presence of propylene glycol alginate increased the stability and intestine-targeted delivery potential of carboxymethyl starch-stabilized emulsions.  FOOD RESEARCH INTERNATIONAL,  157  (111387).  [PMID:35761643] [10.1016/j.foodres.2022.111387]
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11. Liang Liu, Ying Zhang, Shuangjiang Yu, Zhen Zhang, Chaoliang He, Xuesi Chen.  (2018)  pH- and Amylase-Responsive Carboxymethyl Starch/Poly(2-isobutyl-acrylic acid) Hybrid Microgels as Effective Enteric Carriers for Oral Insulin Delivery.  BIOMACROMOLECULES,  19  (6): (2123–2136).  [PMID:29664632] [10.1021/acs.biomac.8b00215]
12. Huimei Cai, Guijie Chen, Chuanyi Peng, Lingyun Xu, Zhengzhu Zhang, Fei Ke, Xiaochun Wan.  (2015)  Enhanced fluoride removal by loading Al/Zr onto carboxymethyl starch sodium: synergistic interactions between Al and Zr.  RSC Advances,  5  (123): (101819-101825).  [10.1039/C5RA18167D]
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25. Mingge Wang, Yu Jiang, Lei Li, Zehui Peng, Jie Wang, Xinqing Duan, Dar-Jen Hsieh, Kuan-Chang Chang.  (2025)  Sodium Carboxymethyl Starch Films with Enhanced Cross-Linking, Electrical, and Mechanical Properties via Supercritical-Assisted Modification.  ACS Sustainable Chemistry & Engineering,  13  (6): (2293-2302).  [10.1021/acssuschemeng.4c06299]
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