| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| S477613-10mg |
10mg |
现货  |
| |
| S477613-50mg |
50mg |
现货 |
|
| 别名 | N-酰基-D-鞘氨醇-1-磷酸胆碱 |
|---|---|
| 英文别名 | N-Acyl-4-sphingenyl-1-O-phosphorylcholine | N-Acyl-D-sphingosine-1-phosphocholine |
| 规格或纯度 | ≥95%(TLC), 来自蛋黄 |
| 英文名称 | Sphingomyelin |
| 生化机理 | 鞘磷脂是 HDL 和质膜中第二丰富的脂质和主要的鞘脂成分。它形成富含胆固醇的脂筏。它在无质膜胆固醇的可用性中起关键作用。 |
| 储存温度 | 避光,-20°C储存,充氩 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
主要含有棕榈酸。
Contains primarily palmitic acid. |
| 纯度 | ≥95%(TLC) |
| pKa值 | pKa: 1.24 |
|---|
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 286-097-2 |
|---|---|
| 分子类型 | 小分子 |
| Smiles | CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)([O-])OCC[N+](C)(C)C)[C@@H](/C=C/CCCCCCCCCCCCC)O |
| Isomeric SMILES | CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)([O-])OCC[N+](C)(C)C)[C@@H](/C=C/CCCCCCCCCCCCC)O |
| PubChem CID | 6453725 |
| 分子量 | 731.08 |
| 敏感性 | 空气，光及湿度敏感 |
|---|---|
| 分子量 | 731.100 g/mol |
| XLogP3 | 13.400 |
| 氢键供体数Hydrogen Bond Donor Count | 2 |
| 氢键受体数Hydrogen Bond Acceptor Count | 6 |
| 可旋转键计数Rotatable Bond Count | 38 |
| 精确质量Exact Mass | 730.599 Da |
| 单同位素质量Monoisotopic Mass | 730.599 Da |
| 拓扑极表面积Topological Polar Surface Area | 108.000 Ų |
| 重原子数Heavy Atom Count | 50 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 826.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 2 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 1 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 1 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| WGK Germany | 3 |
|---|---|
| Merck Index | 6.65694444444444 |
| 个人防护装备 | Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter |
| RIDADR | NONHforallmodesoftransport |
¥247.90
| 1. Xing-Yue Dong, Yan-Xia Huang, Zhan Yang, Xiao-Yang Chu, Jue Wu, Shan Wang, Xin He, Chun-Yan Gao, Xu Chen, Kai Yang, Dong-Liang Zhang, . (2021-07-20) Downregulation of ROR2 promotes dental pulp stem cell senescence by inhibiting STK4-FOXO1/SMS1 axis in sphingomyelin biosynthesis.. Aging cell, 20 ((8)): ( e13430-e13430 ). [PMID:34278704] |
| 2. Qiangqiang Li, Gang Chen, Dan Zhu, Wenwen Zhang, Suzhen Qi, Xiaofeng Xue, Kai Wang, Liming Wu. (2022) Effects of dietary phosphatidylcholine and sphingomyelin on DSS-induced colitis by regulating metabolism and gut microbiota in mice. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 105 (109004). [PMID:35351615] [10.1016/j.jnutbio.2022.109004] |
| 3. Wei Wei, Jin Cheng, Jie Yang, Chen Chen, Qingzhe Jin, Jie Song, Xingguo Wang. (2021) Phospholipid composition and fat globule structure change during low temperature storage of human milk. LWT-FOOD SCIENCE AND TECHNOLOGY, 150 (112050). [10.1016/j.lwt.2021.112050] |
| 4. Chen Fangquan, Tang Hu, Lin Junhao, Xiang Limin, Lu Yanjiao, Kang Rui, Tang Daolin, Liu Jiao. (2024) Macropinocytosis inhibits alkaliptosis in pancreatic cancer cells through fatty acid uptake. CARCINOGENESIS, [PMID:39008332] [10.1093/carcin/bgae045] |
| 5. Yang Yang, Xin Zhang, Jin Yang, Ziyan Wu, Junpeng Li, Ruilong Song, Chuang Meng, Guoqiang Zhu. (2025) N-(3-Oxododecanoyl)-Homoserine Lactone Induces Intestinal Barrier Damage in Piglets via the Lipid Raft-Mediated Apoptosis Pathway. Veterinary Sciences, 12 (3): (233). [10.3390/vetsci12030233] |
| 6. Zhirong Li, Lulu Zhang, Zhanzhong Wang, Xiongli Kang, Huiying Jin, Wenjie Zhao, Jun Zhang, Haiquan Su. (2024) Quantification of Phosphatidylserine Molecules on the Surface of Individual Cells Using Single-Molecule Force Spectroscopy. ANALYTICAL CHEMISTRY, 96 (2): (676-684). [PMID:38173079] [10.1021/acs.analchem.3c03517] |
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