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辛伐他汀-d6

氘代辛伐他汀
    级别和纯度:
  • ≥99 atom% D,≥98%
有货

库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
S334687-1mg
1mg 现货 Stock Image
S334687-5mg
5mg 现货 Stock Image

基本描述

英文别名 2,2-(Dimethyl-d6)butanoic Acid(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro -3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl] -1-naphthalenyl Ester | (+)-Simvastatin-d6 | Cholestat-d6 | Lipex-d6 | Novo-Simvastatin-d6 | Simvotin-d6 | S
规格或纯度 ≥99 atom% D,≥98%
英文名称 Simvastatin-d6
储存温度 -20°C储存,充氩
运输条件 超低温冰袋运输
产品介绍

辛伐他汀-d6是氘化的辛伐他汀,HMG-CoA还原酶的竞争性抑制剂。洛伐他汀的氘代合成类似物。

Simvastatin-d6 is a deuterated Simvastatin, a competitive inhibitor of HMG-CoA reductase. A deuterated synthetic analog of lovastatin.


Application:

Deuterated Simvastatin, a competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic.

纯度 ≥99 atom% D,≥98%

名称和识别符

IIUPAC Name [(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-bis(trideuteriomethyl)butanoate
INCHI 1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1/i4D3,5D3
InChi Key RYMZZMVNJRMUDD-QDGXURMLSA-N
Smiles CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C
Isomeric SMILES [2H]C([2H])([2H])C(CC)(C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C)C([2H])([2H])[2H]
PubChem CID 45040400
分子量 424.6

化学和物理性质

溶解性 Soluble in Dichloromethane, DMF, DMSO, Ether, Ethyl Acetate and Methanol, Chloroform
敏感性 对湿度敏感
熔点 117-120° C

安全和危险性(GHS)

预防措施声明

P264: 处理后要彻底洗手。

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到3个结果

批号(Lot Number) 证书类型 货号
G2229418 分析证书 S334687
G2229420 分析证书 S334687
L2405112 分析证书 S334687

技术文档和文章

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稳定性同位素在药物开发和定制化医学中的应用: 揭示生物标记与动力学生化网络的奥秘
Stable Isotopes in Drug Development and Personalized Medicine: Biomarkers that Reveal Causal Pathway Fluxes and the Dynamics of Biochemical Networks
Stable Isotope Applications
Stable Isotopes in Drug Development and Personalized Medicine: Biomarkers that Reveal Causal Pathway Fluxes and the Dynamics of Biochemical Networks
Stable Isotope Applications
Stable Isotopes in Drug Development and Personalized Medicine: Biomarkers that Reveal Causal Pathway Fluxes and the Dynamics of Biochemical Networks

溶液计算器