L-抗坏血酸-2-磷酸三钠盐

抗坏血酸衍生物；在骨髓来源的MSC中保持分化潜能

24篇引用文献

COA

级别和纯度:

≥96%(HPLC)

CAS编号: 66170-10-3
分子式: C₆H₆Na₃O₉P· xH₂O
分子量: 322.05 (anhydrous basis)
MDL号: MFCD03095479
PubChem编号: 10990876
PubChem SID: 488197030

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货号 (SKU)	包装规格	是否现货
S304311-1g	1g	现货
S304311-5g	5g	现货
S304311-25g	25g	现货
S304311-100g	100g	现货
S304311-500g	500g	现货

查看相关系列

Endogenous Metabolite (978) Glucose Metabolism (3713) Immunology/Inflammation (1938) Metabolic Enzyme/Protease (4889) NF-κB (756) Phosphatase (222) Reactive Oxygen Species (316) 代谢物 (8911)

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基本描述

英文别名	2-phospho-l-ascorbic acid trisodium salt \| CCG-267723 \| Sodium ascorbyl monophosphate;Sodium ascorbyl phosphate \| trisodium;[(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-oxido-5-oxo-2H-furan-4-yl] phosphate \| L-Ascorbic acid 2-phosphate trisodium \| SCHEMBL47301 \| S
规格或纯度	≥96%(HPLC)
英文名称	2-Phospho-L-ascorbic acid trisodium salt
生化机理	用于细胞培养的稳定的抗坏血酸衍生物；与FGF-2联合使用可通过增加HGF的表达来维持骨髓间充质干细胞（MSC）的分化潜能。与N-乙酰半胱氨酸结合使用时，在氧化应激下还具有hMSC的协同保护作用。
应用	L-抗坏血酸-2-磷酸三钠盐已被用作Dulbecco改良Eagle培养基（DMEM）的补充剂，用于培养脂肪来源的干细胞、人间充质干细胞和成骨细胞。
储存温度	室温,干燥
运输条件	常规运输
产品介绍	L-抗坏血酸-2-磷酸三钠盐已被用作Dulbecco改良Eagle培养基（DMEM）的补充剂，用于培养脂肪来源的干细胞、人间充质干细胞和成骨细胞。 L-ascorbic acid-2-phosphate trisodium salt has been used as a supplement to Dulbecco's modified Eagle medium (DMEM) for the culture of adipose derived stem cells, human mesenchymal stem cells and osteoblasts.
纯度	≥96%(HPLC)

名称和识别符

PubChem SID	488197030
分子类型	小分子
IIUPAC Name	trisodium;[(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-oxido-5-oxo-2H-furan-4-yl] phosphate
INCHI	1S/C6H9O9P.3Na/c7-1-2(8)4-3(9)5(6(10)14-4)15-16(11,12)13;;;/h2,4,7-9H,1H2,(H2,11,12,13);;;/q;3*+1/p-3/t2-,4+;;;/m0.../s1
InChi Key	YRWWOAFMPXPHEJ-OFBPEYICSA-K
Smiles	C(C(C1C(=C(C(=O)O1)OP(=O)([O-])[O-])[O-])O)O.[Na+].[Na+].[Na+]
Isomeric SMILES	C([C@@H]([C@@H]1C(=C(C(=O)O1)OP(=O)([O-])[O-])[O-])O)O.[Na+].[Na+].[Na+]
分子量	322.05 (anhydrous basis)

化学和物理性质

溶解性	溶于water, 最高浓度 (mg/mL): 32.2, 最高浓度(mM): 100
熔点	84 °C
分子量	322.050 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	9
可旋转键计数Rotatable Bond Count	3
精确质量Exact Mass	321.944 Da
单同位素质量Monoisotopic Mass	321.944 Da
拓扑极表面积Topological Polar Surface Area	162.000 Å²
重原子数Heavy Atom Count	19
形式电荷Formal Charge	0
复杂度Complexity	357.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	2
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	4

安全和危险性（GHS）

信号词	警告
危险声明	H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
预防措施声明	P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

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批号(Lot Number)	证书类型	货号
A2304217	分析证书	S304311
I2503614	分析证书	S304311
I2503604	分析证书	S304311
I2503612	分析证书	S304311
I2503613	分析证书	S304311
I2503617	分析证书	S304311
G2508423	分析证书	S304311
G2508424	分析证书	S304311
G2508643	分析证书	S304311
G2508665	分析证书	S304311
G2508666	分析证书	S304311
A2515538	分析证书	S304311
A2515545	分析证书	S304311
A2515546	分析证书	S304311
A2515547	分析证书	S304311
B2217364	分析证书	S304311
C2122042	分析证书	S304311
J2218336	分析证书	S304311
E2213158	分析证书	S304311
E2422118	分析证书	S304311
I2403019	分析证书	S304311
J2421259	分析证书	S304311
B2217322	分析证书	S304311
B2217344	分析证书	S304311
B2217373	分析证书	S304311
B2217376	分析证书	S304311
A2304218	分析证书	S304311
A2304229	分析证书	S304311
A2329015	分析证书	S304311
E2304360	分析证书	S304311
A2411070	分析证书	S304311
A2417090	分析证书	S304311

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引用文献

1. Yu Liu, Fangfang Wang, Yawen Liu, Zhigang Zhang, Haiming Hu, Yiqing Wang, Lei Xiong, Junping Zheng, Hongtao Liu. (2023) A label-free AuNPs-based ultrasensitive plasmonic ELISA by alkaline phosphatase and ferrous ion-initiated cascade amplification. SENSORS AND ACTUATORS B-CHEMICAL, (135049). [10.1016/j.snb.2023.135049]
2. Jiansen Lie, Feili Luo, Yafang Liu, Yixuan Yang, Qingling Nie, Xiaochuan Chen, Ruiyun You, Yunzhen Liu, Xiufeng Xiao, Yudong Lu. (2024) Recyclable magnetic nanoparticles combined with TiO2 enrichment and “Off” to “On” SERS assay for sensitive detection of alkaline phosphatase. CHEMICAL ENGINEERING JOURNAL, 479 (147241). [10.1016/j.cej.2023.147241]
3. Meijie Ren, Yongzhen Dong, Jianlong Wang, Jianhan Lin, Lijie Qu, Yang Zhou, Yiping Chen. (2023) Computer vision-assisted smartphone microscope imaging digital immunosensor based on click chemistry-mediated microsphere counting technology for the detection of aflatoxin B1 in peanuts. ANALYTICA CHIMICA ACTA, 1278 (341687). [PMID:37709427] [10.1016/j.aca.2023.341687]
4. Xinyue Yuwen, Yingzhao Zeng, Shilong Ruan, Xin Li, Guosong Lai. (2023) Dual cascade nucleic acid recycling-amplified assembly of hyperbranched DNA nanostructures to construct a novel plasmonic colorimetric biosensing method. ANALYST, 148 (15): (3632-3640). [PMID:37409607] [10.1039/D3AN00689A]
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9. Luyu Wei, Zhilong Wang, Yiping Chen. (2022) Optical Biosensor for Ochratoxin A Detection in Grains Using an Enzyme-Mediated Click Reaction and Polystyrene Nanoparticles. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (46): (14798–14804). [PMID:36372964] [10.1021/acs.jafc.2c05137]
10. Chengpei Du, Lin Qi, Yi Wang, Kanglin Pei, Renwen Zhang, Di Wu, Wenjing Qi. (2022) Fluorescence dual “turn-on” detection of acid phosphatase via fluorescence resonance energy transfer and dual quenching strategy to improve sensitivity. DYES AND PIGMENTS, 205 (110554). [10.1016/j.dyepig.2022.110554]
11. Xiao-Xue Jiang, Pan Li, Meng-Ya Zhao, Rui-Cong Chen, Zhen-Guang Wang, Jia-Xiu Xie, Yun-Kai Lv. (2022) In situ encapsulation of SQDs by zinc ion-induced ZIF-8 growth strategy for fluorescent and colorimetric dual-signal detection of alkaline phosphatase. ANALYTICA CHIMICA ACTA, 1221 (340103). [PMID:35934395] [10.1016/j.aca.2022.340103]
12. Wentao Shi, Xuan Zhang, Lu Bian, Yao Dai, Zhe Wang, Yanjun Zhou, Shuang Yu, Zhijian Zhang, Peng Zhao, Hong Tang, Qing Wang, Xiaojie Lu. (2022) Alendronate crosslinked chitosan/polycaprolactone scaffold for bone defects repairing. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 204 (441). [PMID:35151707] [10.1016/j.ijbiomac.2022.02.007]
13. Dan Zhao, Juan Li, Chuanyun Peng, Shuyun Zhu, Jian Sun, Xiurong Yang. (2019) Fluorescence Immunoassay Based on the Alkaline Phosphatase Triggered in Situ Fluorogenic Reaction of o-Phenylenediamine and Ascorbic Acid. ANALYTICAL CHEMISTRY, 91 (4): (2978–2984). [PMID:30688059] [10.1021/acs.analchem.8b05203]
14. Ruiying Li, Qiang Liu, Yan Jin, Baoxin Li. (2019) Fluorescent enzyme-linked immunoassay strategy based on enzyme-triggered in-situ synthesis of fluorescent copper nanoclusters. SENSORS AND ACTUATORS B-CHEMICAL, 281 (28). [10.1016/j.snb.2018.09.128]
15. Ting Xiao, Jian Sun, Jiahui Zhao, Shuang Wang, Guoyong Liu, Xiurong Yang. (2018) FRET Effect between Fluorescent Polydopamine Nanoparticles and MnO2 Nanosheets and Its Application for Sensitive Sensing of Alkaline Phosphatase. ACS Applied Materials & Interfaces, 10 (7): (6560–6569). [PMID:29384352] [10.1021/acsami.7b18816]
16. Jian Sun, Tao Hu, Chuanxia Chen, Dan Zhao, Fan Yang, Xiurong Yang. (2016) Fluorescence Immunoassay System via Enzyme-Enabled in Situ Synthesis of Fluorescent Silicon Nanoparticles. ANALYTICAL CHEMISTRY, 88 (19): (9789–9795). [PMID:27657654] [10.1021/acs.analchem.6b02847]
17. Xiaolong Zheng, Linlin Sun, Yanan Zhao, Hualin Yang, Yuanhua Zhu, Junxiang Zhang, Die Xu, Xingping Zhang, Yu Zhou. (2024) A fluorescence and colorimetric dual-mode immunoassay for detection of ochratoxin A based on cerium nanoparticles. MICROCHEMICAL JOURNAL, 201 (110419). [10.1016/j.microc.2024.110419]
18. Dan Li, Yutao Shen, Na Li, Xiaolong Li, Mao Li, Zijia Huang, Yong Zhao. (2025) A fluorescent optical fiber sensor for real-time, portable detection of alkaline phosphatase activity. SENSORS AND ACTUATORS B-CHEMICAL, 433 (137568). [10.1016/j.snb.2025.137568]
19. Yu Liu, Yawen Liu, Fangfang Wang, Zhigang Zhang, Haiming Hu, Lei Xiong, Junping Zheng, Hongtao Liu. (2024) A silver auto-catalyzed plasmonic enzyme-linked immunosorbent assay for colorimetric and fluorescent detection of neutrophil gelatinase associated lipocalin (NGAL). MICROCHEMICAL JOURNAL, 206 (111551). [10.1016/j.microc.2024.111551]
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22. Huayue Sun, Huining Chai, Zhishuang Yuan, Kun Yu, Lijun Qu, Xueji Zhang, Guangyao Zhang. (2025) Dual-mode visual fluorescent/colorimetric ratio sensing of alkaline phosphatase in milk based on porphyrinic MOF photonanozyme fibers. FOOD CHEMISTRY, 475 (143289). [PMID:39938265] [10.1016/j.foodchem.2025.143289]
23. Yufeng Liu, Jing Zhang, Yuxin Wan, Cong Li, Shuai Cui, Xuejiao J. Gao, Hui Wei, Dongzhi Yang. (2025) Engineering Perovskite Hydroxide as a Cold-Adapted Oxidase Mimic for Construction of the Robust Low-Temperature Adaptive Biosensors. ACS Sensors, 10 (3): (1844-1856). [PMID:40073385] [10.1021/acssensors.4c02848]
24. Jie Liu, Hao Deng, Bao-Zhu Jia, Ze-Shan Lin, Yu Wang, Hong Wang, Zhen-Lin Xu, Lin Luo. (2024) Ratiometric fluorescence and photothermal dual-mode immunosensor based on MnO2 nanosheets for the detection of isocarbophos. CHEMICAL ENGINEERING JOURNAL, 502 (157951). [10.1016/j.cej.2024.157951]

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