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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| rp184896-10μg |
10μg |
现货 ![]() |
| |
| rp184896-50μg |
50μg |
现货 ![]() |
| |
| rp184896-100μg |
100μg |
现货 ![]() |
| |
| rp184896-1mg |
1mg |
期货 ![]() |
|
| 产品名称 | Recombinant Human HDAC3 Protein |
|---|---|
| 别名 | 重组人HDAC3蛋白 | 重组人组蛋白去乙酰化酶 3 |
| 英文别名 | HD3 | HDAC 3 | HDAC3 | HDAC3_HUMAN | Histone deacetylase 3 | RPD3 | RPD3 2 | RPD3-2 | SMAP45 |
| 规格或纯度 | 无载体, ≥75%(SDS-PAGE), 见COA |
| 生化机理 | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation. Post-translational: Sumoylated in vitro.Deubiquitinated on 'Lys-63'-linked ubiquitin chains by USP38; leading to a decreased level of histone acetylation. |
| 内毒素水平 | <1.0 EU/μg |
| 表达系统 | E. coli |
| 种属 | 人(Human) |
| 氨基酸 | 216-422 aa |
| 序列 | MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHPPKSDGSTSGSGHHHHHHSAGENLYFQGYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDK |
| 蛋白标签 | N-GST & His |
| 无载体 | Yes |
| 无动物源 | No |
| Accession # | O15379 |
| 来源 | 重组表达 |
| 预测分子量 | 51.9 kDa |
| SDS-PAGE | 50.8 kDa, under reducing conditions |
| 物理形态 | 液体 |
|---|---|
| 储存缓冲液 | PBS, 5% Glycerol, pH 7.4 |
| 浓度 | 见COA |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | -20℃ 存储12个月;收货后建议分装,避免反复冻融。 |
| 分子类型 | 蛋白质 |
Recombinant Human HDAC3 Protein (rp184896) - SDS-PAGE
3 μg/lane of Recombinant Human HDAC3 Protein was resolved with SDS-PAGE under reducing (R) condition and visualized by Coomassie® Blue staining, showing a band at 50.8 kDa.
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | rp184896 | |
| 分析证书 | rp184896 | |
| 分析证书 | rp184896 |