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Recombinant Human HDAC3 Protein

    级别和纯度:
  • 无载体
  • ≥75%(SDS-PAGE)
  • 见COA
  • 表达系统: E. coli
  • Accession #: O15379
  • 蛋白标签: N-GST & His
  • 内毒素水平: <1.0 EU/μg
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp184896-10μg
10μg 现货 Stock Image
rp184896-50μg
50μg 现货 Stock Image
rp184896-100μg
100μg 现货 Stock Image
rp184896-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human HDAC3 Protein
别名 重组人HDAC3蛋白 | 重组人组蛋白去乙酰化酶 3
英文别名 HD3 | HDAC 3 | HDAC3 | HDAC3_HUMAN | Histone deacetylase 3 | RPD3 | RPD3 2 | RPD3-2 | SMAP45
规格或纯度 无载体, ≥75%(SDS-PAGE), 见COA
生化机理 Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation. Post-translational: Sumoylated in vitro.Deubiquitinated on 'Lys-63'-linked ubiquitin chains by USP38; leading to a decreased level of histone acetylation.
内毒素水平 <1.0 EU/μg
表达系统 E. coli
种属 人(Human)
氨基酸 216-422 aa
序列 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHPPKSDGSTSGSGHHHHHHSAGENLYFQGYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDK
蛋白标签 N-GST & His
无载体 Yes
无动物源 No
Accession # O15379
来源 重组表达
预测分子量 51.9 kDa
SDS-PAGE 50.8 kDa, under reducing conditions

储存与运输

物理形态 液体
储存缓冲液 PBS, 5% Glycerol, pH 7.4
浓度 见COA
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 -20℃ 存储12个月;收货后建议分装,避免反复冻融。
分子类型 蛋白质

图片

Recombinant Human HDAC3 Protein (rp184896) - SDS-PAGE
3 μg/lane of Recombinant Human HDAC3 Protein was resolved with SDS-PAGE under reducing (R) condition and visualized by Coomassie® Blue staining, showing a band at 50.8 kDa.

质检证书(CoA,COO,BSE/TSE 和分析图谱)

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找到3个结果

批号(Lot Number) 证书类型 货号
ZJ25F0927990 分析证书 rp184896
ZJ25F0927989 分析证书 rp184896
ZJ25F0927988 分析证书 rp184896

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