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Recombinant Human Arginase 1/ARG1 Protein

  • 表达系统: E. coli
  • Accession #: P05089
  • 蛋白标签: N-His
  • 生物活性: Immobilized Recombinant Human Arginase 1/ARG1 Protein (rp181581) at 1.0 μg/mL can bind Liver Arginase Mouse mAb (Ab113273) with the EC50 of 35.09 ng/mL.
  • 内毒素水平: <1.0 EU/μg
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货号 (SKU) 包装规格 是否现货 价格 数量
rp181581-10μg
10μg 现货 Stock Image
rp181581-50μg
50μg 现货 Stock Image
rp181581-100μg
100μg 现货 Stock Image
rp181581-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human Arginase 1/ARG1 Protein
别名 重组人Arginase 1/ARG1蛋白 | 重组人类精氨酸酶 1/ARG1 蛋白
英文别名 AI | ARG1 | Arginase 1 | arginase, liver | Arginase-1 | EC 3.5.3.1 | EC:3.5.3.1 | Liver Arginase | Liver-type arginase | PGIF | Type I Arginase
规格或纯度 Carrier Free, Bioactive, ≥90%(SDS-PAGE)
产品介绍


Purity: ≥90%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxide (NO) synthesis and the development of vascular disease. Arginase also redirects the metabolism of L-arginine to L-ornithine and the formation of polyamines and L-proline, which are essential for smooth muscle cell growth and collagen synthesis. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). In most mammals, Arginase 1 (ARG1) also known as Arginase, liver, which functions in the urea cycle, and is located primarily in the cytoplasm of the liver. The second isozyme, Arginase II, has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body, with most abundance in the kidney and prostate. It may be found at lower levels in macrophages, lactating mammary glands, and brain.

生物活性 Immobilized Recombinant Human Arginase 1/ARG1 Protein (rp181581) at 1.0 μg/mL can bind Liver Arginase Mouse mAb (Ab113273) with the EC50 of 35.09 ng/mL.
内毒素水平 <1.0 EU/μg
表达系统 E. coli
种属 人(Human)
氨基酸 2-322 aa
序列 MHHHHHHSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK​
蛋白标签 N-His
无载体 Yes
无动物源 No
Accession # P05089
来源 重组表达
预测分子量 35.6 kDa
SDS-PAGE 35.6 kDa, under reducing conditions; 35.6 kDa, under non-reducing conditions

储存与运输

储存缓冲液 20mM Tris, 150mM NaCl, 20% glycerol, 1mM DTT, pH7.4
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
分子类型 蛋白质

图片

Recombinant Human Arginase 1/ARG1 Protein (rp181581) - ELISA
Immobilized Recombinant Human Arginase 1/ARG1 Protein (rp181581) at 1.0 μg/mL can bind Liver Arginase Mouse mAb (Ab113273) with the EC₅₀ of 35.09 ng/mL.

Recombinant Human Arginase 1/ARG1 Protein (rp181581) - SDS-PAGE
3 μg/lane of Recombinant Human Arginase 1/ARG1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 35.6 kDa.

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批号(Lot Number) 证书类型 货号
ZJ24F0606798 分析证书 rp181581
ZJ24F0606799 分析证书 rp181581
ZJ24F0606800 分析证书 rp181581

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