Recombinant Feline CD8 alpha Protein

COA

级别和纯度:

无动物源

无载体

无叠氮钠

≥95%(SDS-PAGE)

表达系统: HEK293
Accession #: P41688
蛋白标签: C-His
生物活性: Bioassay data are not available.
内毒素水平: <1.0 EU/μg

有货

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货号 (SKU)	包装规格	是否现货
rp176254-10μg	10μg	现货
rp176254-50μg	50μg	现货
rp176254-100μg	100μg	现货
rp176254-1mg	1mg	期货

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点击查看蛋白信息: CD8A

Accession#: P41688 (1) Cd8a (61) Feline CD8 alpha (1) Gene ID: 493799 (1)

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基本描述

产品名称	Recombinant Feline CD8 alpha Protein
别名	重组猫CD8a蛋白 \| 重组猫 CD8 alpha 蛋白
英文别名	T-cell surface glycoprotein CD8 alpha chain \| CD8a
规格或纯度	Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
产品介绍	Purity: >95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of cytotoxic T-lymphocytes (CTLs). This mechanism enables CTLs to recognize and eliminate infected cells and tumor cells. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
生物活性	Bioassay data are not available.
内毒素水平	<1.0 EU/μg
表达系统	HEK293
种属	猫(Feline)
氨基酸	1-188 aa
序列	MASPVTAQLLPLALLLHAAAAAGPSPFRLSPVRVEGRLGQRVELQCEVLLSSAAPGCTWLFQKNEPAARPIFLAYLSRSRTKLAEELDPKQISGQRIQDTLYSLTLHRFRKEEEGYYFCSVVSNSVLYFSAFVPVFLPVKPTTTPAPRPPTQAPITTSQRVSLRPGTCQPSAGSTVEASGLDLSCDIYHHHHHH
纯度	>95% (SDS-PAGE)
蛋白标签	C-His
无载体	Yes
无动物源	Yes
Accession #	P41688
来源	重组表达
预测分子量	19.2 kDa
SDS-PAGE	26.2-38.3 kDa, under reducing conditions; 23.1-36.7 kDa, under non-reducing conditions

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from PBS, pH7.4
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
分子类型	蛋白质

图片

SDS-PAGE: Recombinant Feline CD8 alpha Protein (rp176254)

Recombinant Feline CD8 alpha Protein (rp176254) - SDS-PAGE
3 μg/lane of Recombinant Feline CD8 alpha Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 26.2-38.3 kDa under reducing conditions and 23.1-36.7 kDa under non-reducing conditions.

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批号(Lot Number)	证书类型	货号
ZJ25F0622327	分析证书	rp176254
ZJ25F0622326	分析证书	rp176254
ZJ25F0622325	分析证书	rp176254

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