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Recombinant Human Thrombopoietin GMP Protein

  • 表达系统: E. coli
  • Accession #: NP_000451.1
  • 蛋白标签: No tag
  • 生物活性: Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.05-0.5 ng/mL. The specific activity of Recombinant Human Thrombopoietin is >1 x 10^7 units/mg, which is calibrated against the human Thrombopoietin reference standard (NIBSC code: 03/124).
  • 内毒素水平: <0.1 EU/μg
有货

库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp167459-GMP-50μg
50μg 期货 Stock Image
rp167459-GMP-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human Thrombopoietin GMP Protein
别名 血小板生成素(TPO)重组蛋白 | 重组人血小板生成素GMP蛋白
英文别名 Megakaryocyte colony-stimulating factor | Megakaryocyte growth and development factor | megakaryocyte stimulating factor | MGDF | MGDFC-mpl ligand | MKCSF | MK-CSF | ML | MPL ligand | MPLLG | MGC163194 | Myeloproliferative leukemia virus oncogene ligand |
规格或纯度 ActiBioPure™, 生物活性, GMP, 无动物源, 无载体, High performance, ≥95%(SDS-PAGE&SEC-HPLC)
生化机理 细胞系特异性细胞因子,影响巨核细胞从其固定的祖细胞增殖和成熟。它在巨核细胞发育的后期发挥作用。它可能是循环血小板的主要生理调节因子。
生物活性 Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.05-0.5 ng/mL. The specific activity of Recombinant Human Thrombopoietin is >1 x 10^7 units/mg, which is calibrated against the human Thrombopoietin reference standard (NIBSC code: 03/124).
内毒素水平 <0.1 EU/μg
表达系统 E. coli
种属 人(Human)
氨基酸 22-195 aa
序列 SPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNEL
蛋白标签 No tag
N-末端序列 Ala-Ser22-Pro-Ala-Pro-Pro-Ala-(Cys)-Asp-Leu
无载体 Yes
无动物源 Yes
Accession # NP_000451.1
来源 重组表达
预测分子量 18.7 kDa
SDS-PAGE 19 kDa, under reducing conditions

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from a 0.2 μm filtered solution in Sodium Acetate.
复溶 Reconstitute at 100-200 μg/mL in sterile, deionized water.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 按供货时的温度≤ -20 ℃保存,至少可保存 12 个月。1 个月,复溶后在无菌条件下 2 至 8 ℃ 保存。3 个月,复溶后无菌条件下 ≤ -28 ℃。收货后建议分装。避免冻融循环。
分子类型 蛋白质

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

溶液计算器