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Recombinant Mouse Activin RIIA Protein

  • 表达系统: HEK293
  • Accession #: P27038
  • 蛋白标签: C-His
  • 生物活性: Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50 for this effect is 6-36 ng/mL in the presence of 3 ng/mL of recombinant human Activin A.
  • 内毒素水平: <0.1 EU/μg
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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp164335-10μg
10μg 现货 Stock Image
rp164335-50μg
50μg 现货 Stock Image
rp164335-100μg
100μg 现货 Stock Image
rp164335-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Mouse Activin RIIA Protein
别名 激活素A受体ⅡA(ACVR2A)重组蛋白
英文别名 activin A receptor, type II | activin A receptor, type IIA | Activin receptor type IIA | activin receptor type-2A | Activin RIIA | ActivinRIIA | ACTRII | ACTRIIA | ACVR2A | ACTR-IIA | AVR2A | EC 2.7.11 | EC 2.7.11.30 | Acvr2 | TactrII
规格或纯度 ActiBioPure™, 生物活性, 无动物源, Carrier Free, High performance, ≥95%(SDS-PAGE)
产品介绍


Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6.

生物活性 Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50 for this effect is 6-36 ng/mL in the presence of 3 ng/mL of recombinant human Activin A.
内毒素水平 <0.1 EU/μg
表达系统 HEK293
种属 小鼠(Mouse)
氨基酸 1-134 aa
蛋白标签 C-His
N-末端序列 MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWERDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPHHHHHH
无载体 Yes
无动物源 Yes
Accession # P27038
来源 重组表达
预测分子量 16 kDa
SDS-PAGE 25 - 35 kDa, under reducing conditions; 25 - 35 kDa, under non-reducing conditions.

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶 Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
分子类型 蛋白质

图片

Recombinant Mouse Activin RIIA Protein (rp164335) - SDS-PAGE
2 μg/lane of Mouse Activin RIIA Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 25 - 35 kDa.

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批号(Lot Number) 证书类型 货号
ZJ25F0420508 分析证书 rp164335
ZJ25F0420507 分析证书 rp164335
ZJ25F0420506 分析证书 rp164335

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