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Recombinant Rat VEGF 164 Protein

  • 表达系统: HEK293
  • Accession #: P16612-2
  • 蛋白标签: No tag
  • 生物活性: Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 0.75‑3.75 ng/mL.
  • 内毒素水平: <0.1 EU/μg
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货号 (SKU) 包装规格 是否现货 价格 数量
rp155249-10μg
10μg 现货 Stock Image
rp155249-50μg
50μg 现货 Stock Image
rp155249-100μg
100μg 现货 Stock Image
rp155249-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Rat VEGF 164 Protein
别名 重组大鼠VEGF 164蛋白 | 重组大鼠血管内皮生长因子A蛋白
英文别名 Vascular Endothelial Growth Factor | MVCD1 | VAS | vascular endothelial growth factor A | Vascular permeability factor | Vasculotropin | VEGF | VEGFA | VEGF-A | MGC70609 | VPF | VEGF111 | VEGF164
规格或纯度 ActiBioPure™, 重组, 无动物源, Carrier Free, High performance, ≥95%(SDS-PAGE)
产品介绍


Function

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor.

生物活性 Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 0.75‑3.75 ng/mL.
内毒素水平 <0.1 EU/μg
表达系统 HEK293
种属 大鼠(Rat)
氨基酸 27-190 aa
序列 APTTEGEQKAHEVVKFMDVYQRSYCRPIETLVDIFQEYPDEIEYIFKPSCVPLMRCAGCCNDEALECVPTSESNVTMQIMRIKPHQSQHIGEMSFLQHSRCECRPKKDRTKPENHCEPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
蛋白标签 No tag
无载体 Yes
无动物源 Yes
Accession # P16612-2
来源 重组表达
预测分子量 19.2 kDa
SDS-PAGE 22 - 28 kDa, under reducing conditions; 40 - 46 kDa, under non-reducing conditions.

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶 Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
分子类型 蛋白质

图片

Recombinant Rat VEGF 164 Protein (rp155249) - SDS-PAGE
2 μg/lane of Recombinant Rat VEGF 164 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 22 - 28 kDa under reducing conditions and 40 - 46 kDa under non-reducing conditions.

Recombinant Rat VEGF 164 Protein (rp155249) - Protein Bioactivity
Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 3.3 ng/mL.

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批号(Lot Number) 证书类型 货号
ZJ25F0319869 分析证书 rp155249
ZJ25F0319868 分析证书 rp155249
ZJ25F0319867 分析证书 rp155249

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