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Recombinant Mouse IL-12/IL-23 p40 Monomer Protein

Recombinant Mouse IL-12/IL-23 p40 Monomer Protein

级别和纯度:

≥95%(SDS-PAGE)

表达系统: HEK293
Accession #: P43432
蛋白标签: C-His
生物活性: Measured by its ability to inhibit IL-23 induced IL-17 secretion by mouse splenocytes. The ED50 for this effect is 3-18 ng/mL.
内毒素水平: <0.1 EU/μg

有货

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货号 (SKU)	包装规格	是否现货
rp154137-10μg	10μg	现货
rp154137-50μg	50μg	现货
rp154137-1mg	1mg	期货
rp154137-100μg	100μg	现货

查看相关系列

点击查看蛋白信息: IL12B

Accession#: P43432 (4) Gene ID: 16160 (4) IL-12 p40 (3) Il12b (17)

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基本描述

产品名称	Recombinant Mouse IL-12/IL-23 p40 Monomer Protein
别名	重组小鼠IL-12/IL-23 p40蛋白 \| 重组小鼠白介素12B蛋白
英文别名	CLMF \| CLMF2 \| Cytotoxic lymphocyte maturation factor 40 kDa subunit \| IL12 p40 \| IL-12 p40 \| IL-12 subunit p40 \| IL12B \| IL-12B \| CLMF p40 \| IL-12BNK cell stimulatory factor chain 2 \| interleukin 12, p40 \| interleukin 12B (natural killer cell stimulatory
规格或纯度	ActiBioPure™, Bioactive, Carrier Free, High performance, ≥95%(SDS-PAGE)
产品介绍	Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
生物活性	Measured by its ability to inhibit IL-23 induced IL-17 secretion by mouse splenocytes. The ED50 for this effect is 3-18 ng/mL.
内毒素水平	<0.1 EU/μg
表达系统	HEK293
种属	小鼠(Mouse)
氨基酸	23-335aa
序列	MWELEKDVYVVEVDWTPDAPGETVNLTCDTPEEDDITWTSDQRHGVIGSGKTLTITVKEFLDAGQYTCHKGGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFNIKSSSSSPDSRAVTCGMASLSAEKVTLDQRDYEKYSVSCQEDVTCPTAEETLPIELALEARQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQVEVSWEYPDSWSTPHSYFSLKFFVRIQRKKEKMKETEEGCNQKGAFLVEKTSTEVQCKGGNVCVQAQDRYYNSSCSKWACVPCRVRSHHHHHH
蛋白标签	C-His
无载体	Yes
无动物源	Yes
Accession #	P43432
来源	重组表达
预测分子量	36.6 kDa
SDS-PAGE	45 - 55 kDa, under reducing conditions; 45 - 55 & 100 -125 kDa, under non-reducing conditions.

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶	Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
分子类型	蛋白质

图片

SDS-PAGE: Recombinant Mouse IL-12/IL-23 p40 Monomer Protein (rp154137)

Recombinant Mouse IL-12/IL-23 p40 Monomer Protein (rp154137) - SDS-PAGE
3 μg/lane of Recombinant Mouse IL-12/IL-23 p40 Monomer Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 45 - 55 kDa under reducing conditions and 45 - 55 & 100 -125 kDa under non-reducing conditions due to glycosylation.

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F1216146	分析证书	rp154137
ZJ24F1216145	分析证书	rp154137
ZJ24F1216147	分析证书	rp154137

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