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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| rp150034-20μg |
20μg |
现货 ![]() |
| |
| rp150034-100μg |
100μg |
现货 ![]() |
| |
| rp150034-1mg |
1mg |
期货 ![]() |
|
| 产品名称 | Recombinant Human PD-L2/B7-DC Protein |
|---|---|
| 别名 | 重组人细胞程序性死亡蛋白1配体2 |
| 英文别名 | B7-DC | bA574F11.2 | Btdc | Butyrophilin B7-DC | Butyrophilin-like Protein | CD273 antigen | CD273 | CD273PD-1 ligand 2 | MGC142240 | PD-1-ligand 2 | PDCD1L2MGC142238 | PDCD1LG2 | PDL2 | PD-L2 | PDL2B7DC | PD-L2PDCD1 ligand 2 | programmed cell death 1 lig |
| 规格或纯度 | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE) |
| 产品介绍 |
Purity >95% HPLC, SDS-PAGE Additional sequence information N-terminal glycine Function Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
| 生物活性 | Immobilized Recombinant Human PD-L2 at 5 μg/mL (100 μL/well) can bind Recombinant Human PD-1 with a linear range of 0.2-1.0 μg/mL. |
| 内毒素水平 | <0.01 EU/μg |
| 表达系统 | HEK293 |
| 种属 | 人(Human) |
| 氨基酸 | 20-219 aa |
| 序列 | LFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPHHHHHH |
| 纯度 | >95%(SDS-PAGE) |
| 蛋白标签 | C-His |
| 无动物源 | Yes |
| Accession # | Q9BQ51 |
| 来源 | 重组表达 |
| 预测分子量 | 23 kDa |
| 物理形态 | 冻干(Lyophilized) |
|---|---|
| 储存缓冲液 | 10mM PBS (PH7.4), containing 5% trehalose, 5% mannitol |
| 复溶 | Reconstitute in water to a concentration of 0.1-1.0 mg/ml. |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -20~-80℃ 下可保存 1 年以上。 |
| 分子类型 | 蛋白质 |
Recombinant Human PD-L2/B7-DC Protein (rp150034) - SDS-PAGE
2 μg/lane of Recombinant Human PD-L2/B7-DC Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 38 - 48 kDa.
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | rp150034 | |
| 分析证书 | rp150034 |
| 1. Latchman, Y Y and 20 more authors.. (2001) PD-L2 is a second ligand for PD-1 and inhibits T cell activation.. Nature immunology, [PMID:11224527] |
| 2. Tseng, S Y SY and 9 more authors.. (2001) B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells.. The Journal of experimental medicine, (2): [PMID:11283156] |
| 3. Humphray, S J SJ and 147 more authors.. (2004) DNA sequence and analysis of human chromosome 9.. Nature, (27): [PMID:15164053] |
| 4. He, Xian-Hui XH, Liu, Yi Y, Xu, Li-Hui LH and Zeng, Yao-Ying YY.. (2004) Cloning and identification of two novel splice variants of human PD-L2.. Acta biochimica et biophysica Sinica, [PMID:15253154] |
| 5. Zhang, Zemin Z and Henzel, William J WJ.. (2004) Signal peptide prediction based on analysis of experimentally verified cleavage sites.. Protein science : a publication of the Protein Society, [PMID:15340161] |