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Recombinant Human IFN-alpha-1a Protein

  • 表达系统: HEK293
  • Accession #: P01562
  • 蛋白标签: C-His
  • 生物活性: Measured by its ability to stimulate GBP2 expression in 293T human embryonic kidney cells. 0.1-1 ng/mL of Recombinant Human IFNA1 can effectively Stimulating GBP2 expression.
  • 内毒素水平: <0.1 EU/μg
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库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp147739-10μg
10μg 现货 Stock Image
rp147739-50μg
50μg 现货 Stock Image
rp147739-100μg
100μg 现货 Stock Image
rp147739-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human IFN-alpha-1a Protein
别名 干扰素α(IFNa)活性蛋白 | 重组人 IFN-alpha-1a 蛋白
英文别名 IFN-alpha-1/13 | Interferon alpha-D | LeIF D | Interferon alpha 1 | Interferon alpha-1/13 | Interferon alpha-D | Interferon alpha1 | Interferon, alpha 13 | LeIF D | IFNalpha 1 | IFN-alpha 1 | IFL | IFN | IFN alpha | IFN alpha 1/13 | IFN alpha 1b | IFN alp
规格或纯度 无动物源, Carrier Free, 生物活性, ActiBioPure™, High performance, ≥95%(SDS-PAGE)
产品介绍


Function
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.

生物活性 Measured by its ability to stimulate GBP2 expression in 293T human embryonic kidney cells. 0.1-1 ng/mL of Recombinant Human IFNA1 can effectively Stimulating GBP2 expression.
内毒素水平 <0.1 EU/μg
表达系统 HEK293
种属 人(Human)
氨基酸 24-189 aa (Q114A)
序列 MCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFGFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYAQLNDLEACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTNLQERLRRKEHHHHHH
蛋白标签 C-His
无载体 Yes
无动物源 Yes
Accession # P01562
来源 重组表达
预测分子量 20 kDa
SDS-PAGE 15 - 18 kDa, under reducing conditions; 15 - 18 kDa, under non-reducing conditions.

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶 Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
分子类型 蛋白质

图片

Recombinant Human IFN-alpha-1a Protein (rp147739) - SDS-PAGE
3 μg/lane of Recombinant Human IFN-alpha-1a Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 15 -18 kDa.

质检证书(CoA,COO,BSE/TSE 和分析图谱)

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找到3个结果

批号(Lot Number) 证书类型 货号
ZJ24F1012641 分析证书 rp147739
ZJ24F1012642 分析证书 rp147739
ZJ24F1012643 分析证书 rp147739

引用文献

1. Zoon, K C KC and 6 more authors..  (1992)  Purification and characterization of multiple components of human lymphoblastoid interferon-alpha..  The Journal of biological chemistry,  (25): [PMID:1634550]
2. Capon, D J DJ, Shepard, H M HM and Goeddel, D V DV..  (1985)  Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides..  Molecular and cellular biology,  [PMID:2985969]
3. Taniguchi, T T and 5 more authors..  (1980)  Human leukocyte and fibroblast interferons are structurally related..  Nature,  (19): [PMID:6157095]
4. Mantei, N N and 5 more authors..  (1980)  The nucleotide sequence of a cloned human leukocyte interferon cDNA..  Gene,  [PMID:6157600]
5. Goeddel, D V DV and 9 more authors..  (1981)  The structure of eight distinct cloned human leukocyte interferon cDNAs..  Nature,  (5): [PMID:6163083]
6. Weber, H H and Weissmann, C C..  (1983)  Formation of genes coding for hybrid proteins by recombination between related, cloned genes in E. coli..  Nucleic acids research,  (25): [PMID:6310510]
7. Todokoro, K K, Kioussis, D D and Weissmann, C C..  (1984)  Two non-allelic human interferon alpha genes with identical coding regions..  The EMBO journal,  [PMID:6479148]
8. Nyman, T A TA, Tölö, H H, Parkkinen, J J and Kalkkinen, N N..  (1998)  Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes..  The Biochemical journal,  (15): [PMID:9425112]
9. Hussain, M M, Ni, D D, Gill, D D and Liao, M J MJ..  (2000)  IFN-alpha1a gene is the major variant in the North American population..  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research,  [PMID:11032395]
10. Kimura, Tominori T, Hashimoto, Iwao I, Nishizawa, Mikio M, Ito, Seiji S and Yamada, Hisao H..  (2010)  Novel cis-active structures in the coding region mediate CRM1-dependent nuclear export of IFN-α 1 mRNA..  Medical molecular morphology,  [PMID:20857263]
11. Ouyang, Songying S and 16 more authors..  (2012)  Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus..  Journal of molecular medicine (Berlin, Germany),  [PMID:22307521]
12. Henco, K K and 9 more authors..  (1985)  Structural relationship of human interferon alpha genes and pseudogenes..  Journal of molecular biology,  (20): [PMID:4057246]

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