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(R)-泛酰巯基乙胺

COA COA
    级别和纯度:
  • ≥95%(HPLC)
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
R464033-10mg
 10mg 现货 Stock Image
R464033-50mg
 50mg 现货 Stock Image
R464033-100mg
 100mg 现货 Stock Image
R464033-250mg
 250mg 现货 Stock Image
R464033-500mg
 500mg 期货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
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代谢物 (8911)
main product photo

基本描述

别名 泛硫醇 | (2 R )-2,4-二羟基- N -[3-[(2-巯基乙基)氨基]-3-氧丙基]-3,3-二甲基丁酰胺 | ( R )-2,4-二羟基- N -[2-[(2-巯基乙基)氨基甲酰] 乙基]-3,3-二甲基丁酰胺 | ( D )-(+)-泛硫乙胺, N -(泛酰)-β-氨基乙硫醇 | 保加利亚乳酸杆菌生长因子
英文别名 PANTETHEINE [MI] | (R)-Pantetheine, >=95.0% (HPLC) | .ALPHA.,.GAMMA.-DIHYDROXY-.BETA.-DIMETHYLBUTYRYL-.BETA.-ALANYL-.BETA.-AMINOETHANETHIOL | Butanamide, 2,4-dihydroxy-N-(3-((2-mercaptoethyl)amino)-3-oxopropyl)-3,3-dimethyl-, (R)- | (R)-2,4-DIHYDROXY-N-[3
规格或纯度 ≥95%(HPLC)
英文名称 (R)-Pantetheine
生化机理 代谢产物在碳青霉烯类生物合成、泛酸和 CoA 生物合成及次级代谢产物的生物合成。
储存温度 -20°C储存,充氩
运输条件 超低温冰袋运输
产品介绍

(R)-Pantetheine 是 CoA 的生物合成前体。 (R)-Pantetheine 及其相应的二硫化物泛硫乙胺，作为辅酶 A (CoA) 的构建单元在代谢中起关键作用

Product Describtion:

(R)-Pantetheine is the biosynthetic precursor to CoA. (R)-Pantetheine and its corresponding disulfide pantethine, play a key role in metabolism as a building block of coenzyme A (CoA)
纯度 ≥95%(HPLC)

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

分子类型 小分子
IIUPAC Name (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(2-sulfanylethylamino)propyl]butanamide
INCHI 1S/C11H22N2O4S/c1-11(2,7-14)9(16)10(17)13-4-3-8(15)12-5-6-18/h9,14,16,18H,3-7H2,1-2H3,(H,12,15)(H,13,17)/t9-/m0/s1
InChi Key ZNXZGRMVNNHPCA-VIFPVBQESA-N
Smiles CC(C)(CO)C(C(=O)NCCC(=O)NCCS)O
Isomeric SMILES CC(C)(CO)[C@H](C(=O)NCCC(=O)NCCS)O
PubChem CID 439322
UN Number 2811
分子量 278.37
Beilstein号 1714196

化学和物理性质

溶解性 Soluble in DMSO；( < 1 mg/ml refers to the product slightly soluble or insoluble )
敏感性 对空气敏感；易吸潮
比旋光度 [α]/D 17±2°, c = 1 in H2O
闪点(℉) Not applicable
闪点(℃) Not applicable
分子量 278.370 g/mol
XLogP3 -1.000
氢键供体数Hydrogen Bond Donor Count 5
氢键受体数Hydrogen Bond Acceptor Count 5
可旋转键计数Rotatable Bond Count 8
精确质量Exact Mass 278.13 Da
单同位素质量Monoisotopic Mass 278.13 Da
拓扑极表面积Topological Polar Surface Area 99.700 Ų
重原子数Heavy Atom Count 18
形式电荷Formal Charge 0
复杂度Complexity 284.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 1
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS06
信号词 危险
危险声明

H301: 吞咽会中毒
预防措施声明

P264: 处理后要彻底洗手。

P270: 使用本产品时，请勿进食、饮水或吸烟。

P321: 特殊处理（请参阅此标签上的...）。

P330: 漱口

P301+P310: 如误吞咽：立即呼叫急救中心/医生。

P405: 密闭存放

P501: 将内容物/容器处理到。。。
Class 6.1
RIDADR UN 2811 6.1 / PGIII

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到9个结果

批号(Lot Number) 证书类型 货号
K2328250 分析证书 R464033
K2328251 分析证书 R464033
K2328252 分析证书 R464033
K2328253 分析证书 R464033
K2328254 分析证书 R464033
K2328255 分析证书 R464033
K2328256 分析证书 R464033
K2328257 分析证书 R464033
K2328258 分析证书 R464033

可替换产品

  1. D-泛醇
    D-泛醇
    • ≥98%

    ¥29.90

  2. D-泛硫乙胺
    D-泛硫乙胺
    • 80% in H2O

    ¥181.90

引用文献

1. H Kleinkauf,R Roskoski,F Lipmann.  (1971-09-01)  Pantetheine-linked peptide intermediates in gramicidin S and tyrocidine biosynthesis..  Proceedings of the National Academy of Sciences of the United States of America,  68  ((9)): (2069-2072).  [PMID:4943784]
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6. Patrice Brassard,Morten Zaar,Pia Thaning,Niels H Secher,Jaya B Rosenmeier.  (2015-11-21)  Sympathetic Vasoconstrictor Responsiveness of the Leg Vasculature During Experimental Endotoxemia and Hypoxia in Humans..  Critical care medicine,  44  ((4)): (755-763).  [PMID:26588830]
7. Semra Kaya,Cihan Kaçar,Bülent Polat,Armağan Çolak,Duygu Kaya,I Safa Gürcan,Heinrich Bollwein,Selim Aslan.  (2016-09-28)  Association of luteal blood flow with follicular size, serum estrogen and progesterone concentrations, and the inducibility of luteolysis by PGF.  Theriogenology,  87  (167-172).  [PMID:27671290]
8. Matthew F Crum,Natalie L Trevaskis,Colin W Pouton,Christopher J H Porter.  (2016-12-22)  Transient Supersaturation Supports Drug Absorption from Lipid-Based Formulations for Short Periods of Time, but Ongoing Solubilization Is Required for Longer Absorption Periods..  Molecular pharmaceutics,  14  ((2)): (394-405).  [PMID:28002666]
9. Laura B Ferguson,Lingling Zhang,Daniel Kircher,Shi Wang,R Dayne Mayfield,John C Crabbe,Richard A Morrisett,R Adron Harris,Igor Ponomarev.  (2018-08-01)  Dissecting Brain Networks Underlying Alcohol Binge Drinking Using a Systems Genomics Approach..  Molecular neurobiology,  56  ((4)): (2791-2810).  [PMID:30062672]
10. Johanna Busch,Lea Berrang-Ford,Sierra Clark,Kaitlin Patterson,Emma Windfeld,Blanaid Donnelly,Shuaib Lwasa,Didacus Namanya,Sherilee L Harper.  (2019-05-03)  Is the effect of precipitation on acute gastrointestinal illness in southwestern\xa0Uganda different between Indigenous and non-Indigenous communities?.  PloS one,  14  ((5)): (e0214116-e0214116).  [PMID:31048893]
11. Lima, et al..  (2020)  Evaluation of the potential virulence of Candida haemulonii species complex and Candida auris isolates in Caenorhabditis elegans as an in vivo model and correlation to their biofilm production capacity..  Microbial Pathogenesis,  148  (104461-104461).  [PMID:32835773]
12. C T Wittwer,D Burkhard,K Ririe,R Rasmussen,J Brown,B W Wyse,R G Hansen.  (1983-08-25)  Purification and properties of a pantetheine-hydrolyzing enzyme from pig kidney..  The Journal of biological chemistry,  258  ((16)): (9733-9738).  [PMID:6885768]
13. C Wittwer,B Wyse,R G Hansen.  (1982-05-15)  Assay of the enzymatic hydrolysis of pantetheine..  Analytical biochemistry,  122  ((2)): (213-222).  [PMID:7114442]
14. P Dykes,S Bradbury.  (2017-09-08)  Comparing the effectiveness and wash-off resistance of skin barrier creams: a healthy volunteer study..  Journal of wound care,  26  ((9)): (552-557).  [PMID:28880764]
15. Janneke Keemink,Christel A S Bergström.  (2018-02-28)  Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations..  Pharmaceutical research,  35  ((4)): (74-74).  [PMID:29484506]
16. Jun Yang,Xuekun Li,Jirui Xu,Yuzhong Cao,Yun Zhang,Liping Wang,Sheng Jiang.  (2018-05-02)  Development of an optical defect inspection algorithm based on an active contour model for large steel roller surfaces..  Applied optics,  57  ((10)): (2490-2498).  [PMID:29714233]
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18. Haeju Jo,Moonseok Kang,Geon-Woo Park,Byung-Jun Kim,Chang Yong Choi,Hee Sang Park,Sunmi Shin,Wookjin Lee,Yong-Sik Ahn,Jong Bae Jeon.  (2020-09-25)  Effects of Cooling Rate during Quenching and Tempering Conditions on Microstructures and Mechanical Properties of Carbon Steel Flange..  Materials (Basel, Switzerland),  13  ((18)): [PMID:32967133]
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