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哌嗪-N,N'-二(2-乙磺酸)

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
P755828-50g
50g 期货 Stock Image
P755828-250g
250g 期货 Stock Image

基本描述

规格或纯度 BioReagent, 分子生物学级, ≥99.5%(T)
英文名称 PIPES
可用pH范围 6.1-7.5
储存温度 室温
运输条件 常规运输
产品介绍

Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics.: The use of PIPES buffer in this study was integral to maintaining the stability of immunoglobulin G during differential scanning fluorimetry. This method is crucial for evaluating the stability of antibody-based therapeutics (Moggridge et al., 2017).


  • Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics.: The use of PIPES buffer in this study was integral to maintaining the stability of immunoglobulin G during differential scanning fluorimetry. This method is crucial for evaluating the stability of antibody-based therapeutics (Moggridge et al., 2017).

纯度 ≥99.5%(T)

名称和识别符

EC号 227-057-6
IIUPAC Name 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid
INCHI 1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
InChi Key IHPYMWDTONKSCO-UHFFFAOYSA-N
Smiles C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)O
Isomeric SMILES C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)O
分子量 302.37
Beilstein号 817713
Reaxy-Rn 817713
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=817713&ln=

化学和物理性质

溶解性 0.1 M NaOH: 0.1 M at 20 °C, clear, colorless
熔点 >300°C
分子量 302.400 g/mol
XLogP3 -6.700
氢键供体数Hydrogen Bond Donor Count 2
氢键受体数Hydrogen Bond Acceptor Count 8
可旋转键计数Rotatable Bond Count 6
精确质量Exact Mass 302.061 Da
单同位素质量Monoisotopic Mass 302.061 Da
拓扑极表面积Topological Polar Surface Area 132.000 Ų
重原子数Heavy Atom Count 18
形式电荷Formal Charge 0
复杂度Complexity 397.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

信号词 Warning
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激

H302: 吞食有害

预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。

WGK Germany 3
Merck Index 7479
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

此产品的引用文献

引用文献

1. Kuan Cheng, Zesheng Yang, Guojun Chen, Shiwen Hu, Chao Guo, Yang Yang, Shan Wang, Ying Wang, Haibo Dong, Milan Wang, Pengfei Cheng, Tongxu Liu.  (2024)  A comparative study on the stability of Fe(III) minerals formed by the nitrate/nitrite-reducing Fe(II) oxidation processes.  CHEMICAL GEOLOGY,  670  (122446).  [10.1016/j.chemgeo.2024.122446]
2. Yu Wang, Jia-le Wang, Ke Li, Jing-jing Yuan, Bo Chen, Yun-tao Wang, Jun-guang Li, Yan-hong Bai.  (2024)  Effect of chickpea protein modified with combined heating and high-pressure homogenization on enhancing the gelation of reduced phosphate myofibrillar protein.  FOOD CHEMISTRY,  (141180).  [PMID:39276541] [10.1016/j.foodchem.2024.141180]
3. Shuang Li, Yao Huang, Junhao Shen, Shengjun Mao, Rong Peng, Hui Liu.  (2024)  Iron transformation and hydroxyl radical production during mixing surface water and groundwater in the riparian zone: Effects of bicarbonate and surface water-groundwater ratio.  APPLIED GEOCHEMISTRY,  168  (106017).  [10.1016/j.apgeochem.2024.106017]

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