基本描述

别名	软脂酸 \| 十六烷酸 \| 鲸蜡酸 \| 十六酸
英文别名	1-Pentadecanecarboxylic acid \| Cetylic acid \| Hexadecanoic acid \| NSC 5030 \| PamOH
规格或纯度	BioReagent, ≥99%
英文名称	Palmitic acid
生化机理	棕榈酸是一种直链16碳脂肪酸。富含棕榈酸以及月桂酸和肉豆蔻酸的饮食，与血清中低密度脂蛋白胆固醇水平升高有关。棕榈酸是脂肪生成过程产生的第一种脂肪酸。它是乙酰辅酶A羧化酶（ACC）的负调节因子，与脂肪酸诱导的胰岛素抵抗有关。棕榈酸（PA）是膜磷脂（PL）和脂肪三酰基甘油（TAG）的成分。棕榈酸水平升高促进动脉粥样硬化、2型糖尿病、神经退行性疾病、肥胖和癌症的病理生理发展。PA通过调节p38丝裂原活化蛋白激酶（MAPK）途径促进内皮细胞的凋亡，并有利于TNF-α的表达和活性氧的积累。PA促进肝细胞中的白细胞介素8（IL-8）合成，导致肝炎。PA通过与toll样受体4（TLR4）的相互作用，诱导心肌细胞的炎性损伤。
储存温度	室温
运输条件	常规运输
产品介绍	棕榈酸已被用于：作为胎盘绒毛组织培养物的培养基补充剂作为激素小球的组分，用于小鼠卵巢植入用于诱导人单核细胞THP-1的免疫相关GTP酶M（IRGM）的表达 Palmitic acid has been used: as a medium supplement in chorionic villous tissue culture form placenta as a component of hormone pellet for implantation in mice ovary for inducing expression of immunity-related GTPase M (IRGM) in human monocytic cell line, THP-1
纯度	≥99%

名称和识别符

EC号	200-312-9
分子类型	未知
IIUPAC Name	hexadecanoic acid
INCHI	1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)
InChi Key	IPCSVZSSVZVIGE-UHFFFAOYSA-N
Smiles	CCCCCCCCCCCCCCCC(=O)O
Isomeric SMILES	CCCCCCCCCCCCCCCC(=O)O
关联CAS	57-10-3
NSC Number	5030
MeSH Entry Terms	Acid, Hexadecanoic;Acid, Palmitic;Calcium Palmitate;Hexadecanoic Acid;Palmitate, Calcium;Palmitate, Sodium;Palmitic Acid;Sodium Palmitate
分子量	256.42
Beilstein号	607489
Reaxy-Rn	607489
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=607489&ln=

化学和物理性质

溶解性	chloroform: 0.5 M, clear, colorless
密度	0.852 g/mL at 25 °C (lit.)
折光率	1.4273
闪点(℉)	235.4 °F
闪点(℃)	206℃
沸点	271.5°C
熔点	62°C
分子量	256.420 g/mol
XLogP3	6.400
氢键供体数Hydrogen Bond Donor Count	1
氢键受体数Hydrogen Bond Acceptor Count	2
可旋转键计数Rotatable Bond Count	14
精确质量Exact Mass	256.24 Da
单同位素质量Monoisotopic Mass	256.24 Da
拓扑极表面积Topological Polar Surface Area	37.300 Å²
重原子数Heavy Atom Count	18
形式电荷Formal Charge	0
复杂度Complexity	178.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

WGK Germany	3
RTECS	RT4550000
Merck Index	6996
个人防护装备	dust mask type N95 (US),Eyeshields,Gloves

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此产品的引用文献

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引用文献

1. Hongxu Zhou, Qing Jiang, Xin He, Xian Fu, Jun-Yan Liu. (2024) A complementary method with PFBBr-derivatization based on GC-EI-MS platform for the simultaneous quantitation of short-, medium- and long -chain fatty acids in murine plasma and feces samples. Analytical Methods, [PMID:38562090] [10.1039/D3AY02271D]
2. Xuhui Xia, Peng Zhao, Jia Zheng, Xuheng Li, Xin Zeng, Dianhui Men, Yiyao Luo, Changjun Hou, Danqun Huo. (2025) A novel quantum dot-based ratiometric fluorescence sensor array: For reducing substances detection and Baijiu quality discrimination. ANALYTICA CHIMICA ACTA, 1347 (343785). [PMID:40024655] [10.1016/j.aca.2025.343785]
3. Ruiyu Wu, Runping Liu, Ranyun Chen, Yijie Li, Xiaoyong Xue, Yinhao Zhang, Fanghong Li, Jiaorong Qu, Lingling Qin, Chen Wang, Xiaojiaoyang Li. (2025) Aurantio-obtusin improves obesity and protects hepatic inflammation by rescuing mitochondrial damage in overwhelmed brown adipose tissue. Chinese Medicine, 20 (41). [PMID:40133913] [10.1186/s13020-025-01097-y]
4. Liangxiu Wu, Weicheng Lai, Lanlan Li, Sen Yang, Fengjuan Li, Chen Yang, Xiaobing Gong, Liangyan Wu. (2024) Autophagy Regulates Ferroptosis-Mediated Diabetic Liver Injury by Modulating the Degradation of ACSL4. Journal of Diabetes Research, 2024 (1): (7146054). [PMID:39741964] [10.1155/jdr/7146054]
5. Jiajun Yang, Siyu Hou, Yuhui Zhao, Zhaoyang Sun, Lilin Zhang, Yan Deng, Xiaoli Shang, Hanjie Yu, Zheng Li, Hongmei Li. (2025) Buckwheat protein-derived peptide ameliorates insulin resistance by directing O-linked N-acetylglucosamine transferase to regulate the SIRT1/PGC1α pathway. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 304 (140925). [PMID:39947565] [10.1016/j.ijbiomac.2025.140925]
6. Wu Yachen, Zheng Wenzhong, Xu Guofeng, Zhu Lijun, Li Zhiqiang, Chen Jincao, Wang Lianrong, Chen Shi. (2024) C9orf72 controls hepatic lipid metabolism by regulating SREBP1 transport. CELL DEATH AND DIFFERENTIATION, (1-15). [PMID:38816580] [10.1038/s41418-024-01312-7]
7. Lu Zhang, Xujia Cai, Yongzhe Cheng, Shiyi Chen, Min Zhang, Hongyang Zhang, Ping Hu. (2025) Chemical Profiling and Quality Evaluation of Gualou-Xiebai Herbal Pair by Liquid Chromatography-Tandem Mass Spectrometry With Feature-Based Molecular Network and High-Performance Liquid Chromatography With Charged Aerosol Detector. JOURNAL OF SEPARATION SCIENCE, 48 (3): (e70108). [PMID:40021454] [10.1002/jssc.70108]
8. Liu Hongxu, Yao Maojin, Ren Jiaoyan. (2024) Codonopsis pilosula-derived glycopeptide dCP1 promotes the polarization of tumor-associated macrophage from M2-like to M1 phenotype. CANCER IMMUNOLOGY IMMUNOTHERAPY, 73 (7): (1-24). [PMID:38743074] [10.1007/s00262-024-03694-6]
9. Yin-Xu Pan, Qiu-Hui Xu, Dilshad Hussain, Qin-Feng Zhang, Jian-Li Chen, Dan Luo, Hua-Ming Xiao. (2024) Computational 1H nuclear magnetic resonance chemical shifts for furan fatty acid discovering in oxidation process of plant oil. MICROCHEMICAL JOURNAL, (112542). [10.1016/j.microc.2024.112542]
10. Zixi Hu, Luyao Zhan, Yingying Zhang, Luping Sun, Xingchi Wang, Yongkun Liu, Haitao Ma, Mei Wang, Bin Ding, Ying Ma, Jianyong Yu. (2025) Deep Learning-Assisted Electro-Thermochromic Fluorescent Fibers for Self-Adaptive Intelligent Display in Dynamic Environments. Advanced Optical Materials, (2403126). [10.1002/adom.202403126]
11. Mengdi Zhang, Jinliang Ji, Yuanyuan Lei, Fujian Qin, Yitong Tao, Ning Li, Jinlei Bian, Zhiyu Li, Maode Lai, Zhixia Qiu. (2025) Dual inhibition of hepatic ACLY and ACSS2: a synergistic approach to combat NAFLD through lipogenesis reduction and mitochondrial enhancement. PHARMACOLOGICAL RESEARCH, (107706). [PMID:40127788] [10.1016/j.phrs.2025.107706]
12. Xingyu Lin, Hongsheng Lu, Ruoxin Zhang, Yingjiang Chen, Baiwen Huang. (2025) Dual-functionality of CO2-responsive ionic liquids for CO2 storage: Fatty acid particles re-precipitation and clay swelling inhibition. CHEMICAL ENGINEERING RESEARCH & DESIGN, 217 (64). [10.1016/j.cherd.2025.03.024]
13. Yapeng Zhang, Zhidong Ma, Wenqiang Li, Chenwen Liu, Huipeng Gao, Meng Wang, Lanpeng Li, Quan Zhang, Bo Lv, Lei Qin, Chun Li. (2025) Dynamic regulation and enhancement of synthetic network for efficient biosynthesis of monoterpenoid α-pinene in yeast cell factory. BIORESOURCE TECHNOLOGY, (132064). [PMID:39809385] [10.1016/j.biortech.2025.132064]
14. Dami Li, Yaoyao Zhang, Xing Qiao, Shangde Sun. (2025) Effects of substitution sites and acyl chain length on antioxidant capacity and bioaccessibility of high-active resveratrol monoesters in vitro. FOOD CHEMISTRY, 480 (143845). [PMID:40112713] [10.1016/j.foodchem.2025.143845]
15. Luyao Zhan, Wanxuan Xu, Zixi Hu, Jiayin Fan, Luping Sun, Xingchi Wang, Yingying Zhang, Xiaodi Shi, Bin Ding, Jianyong Yu, Ying Ma. (2024) Full-Color “Off–On” Thermochromic Fluorescent Fibers for Customizable Smart Wearable Displays in Personal Health Monitoring. Small, (2310762). [PMID:38366074] [10.1002/smll.202310762]
16. Junfeng Wang, Xuejiao Sun, Lei Gao, Shuyu Tian, Mengqi Zhang, Fei Huang, Jianjun Tian. (2025) Green Synthesis of Luminous Indium Phosphide Nanocrystals. INORGANIC CHEMISTRY, 64 (6): (3111-3119). [PMID:39889246] [10.1021/acs.inorgchem.4c05511]
17. Lingyu Song, Yali Huang, Lu Liu, Xuebing Chang, Laying Hu, Guifang Wang, Lifen Xu, Tian Zhang, Yuanyuan Wang, Ying Xiao, Hong Yang, Suye Ran, Qing Shi, Tuanlao Wang, Mingjun Shi, Yuxia Zhou, Bing Guo. (2025) Meteorin-like alleviates hepatic steatosis by regulating hepatic triglyceride secretion and fatty acid oxidation. Cell Reports, 44 [PMID:39918960] [10.1016/j.celrep.2025.115246]
18. Xiaoyu Shen, Jiamei Zhang, Zhou Zhou, Ruiqun Yu. (2024) PLIN5 Suppresses Lipotoxicity and Ferroptosis in Cardiomyocyte via Modulating PIR/NF-κB Axis. International Heart Journal, [PMID:38749744] [10.1536/ihj.24-002]
19. Zhixin Lei, Xiaoli Cai, Juan Wan, Ze Li, Taolei Sun. (2025) Preparation and characterization of tildipirosin-loaded solid lipid nanoparticles for the treatment of intracellular Staphylococcus aureus infections. Biomaterials Science, 13 (5): (1272-1285). [PMID:39878017] [10.1039/D4BM01428F]
20. Ning Wang, Siyu Xie, Peng Liu, Leting Wang, Chao Zhong, Jun Yu, Manman Qin, Huanwen Chen. (2025) Quality evaluation of Semen Platycladi samples from different origins by Internal Extractive Electrospray Ionization Mass Spectrometry. Analytical Methods, [PMID:39967485] [10.1039/D4AY01881H]
21. Ranyi Luo, Yinhao Zhang, Hong Wang, Bing Xu, Jiaorong Qu, Shuwen Duan, Runping Liu, Jia Liu, Shuo Li, Xiaojiaoyang Li. (2024) Radix Rehmanniae Praeparata extracts ameliorate hepatic ischemia-reperfusion injury by restoring lipid metabolism in hepatocytes. JOURNAL OF ETHNOPHARMACOLOGY, 335 (118702). [PMID:39168395] [10.1016/j.jep.2024.118702]
22. Yongmei Guo, Zixi Hu, Luyao Zhan, Yongkun Liu, Luping Sun, Ying Ma. (2024) Stretchable Thermochromic Fluorescent Fibers Based on Self-Crystallinity Phase Change for Smart Wearable Displays. Polymers, 16 (24): (3575). [PMID:39771427] [10.3390/polym16243575]
23. Chunda Ji, Zekang Lu, Hongxin Zhao, Shuitao Gao, Jianbin Huang, Xinxian Ma, Bin Zhang, Yun Yan. (2025) Strong but Reversible Super Fatty Acid Adhesives with Adjustable On–Off Temperature. ACS Applied Materials & Interfaces, [PMID:40063702] [10.1021/acsami.4c22030]

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货号 (SKU)	包装规格	是否现货
P755719-5g	5g	期货
P755719-25g	25g	期货
P755719-100g	100g	期货

棕榈酸

库存信息

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基本描述

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

此产品的引用文献

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器