红倍酚

Phenols Polyphenols

COA

级别和纯度:

Moligand™

≥96%

CAS编号: 569-77-7
分子式: C₁₁H₈O₅
分子量: 220.17

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货号 (SKU)	包装规格	是否现货
P649449-1mg	1mg	现货
P649449-5mg	5mg	现货
P649449-25mg	25mg	现货
P649449-100mg	100mg	现货

查看相关系列

Amino Acid/Protein Metabolism (4559) Metabolic Enzyme/Protease (4889) Phenols Polyphenols (41) 黄嘌呤氧化酶 (24)

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基本描述

别名	红没食子酸 \| 2,3,4,6-四羟基-5H-苯并[7]轮烯-5-酮 \| 红没食子酸 \| 红陪酚
英文别名	2,3,4,6-Tetrahydroxy-5H-benzo[7]annulen-5-one \| NCI 35676 \| NSC 35676 \| NSC 646653
规格或纯度	Moligand™, ≥96%
英文名称	Purpurogallin
生化机理	Purpurogallin 是一种从柞树属植物中提取的天然酚，具有强效的黄嘌呤氧化酶（XO）抑制活性，IC50 为 0.2 µM。Purpurogallin 具有抗氧化和抗炎作用。
储存温度	-20°C储存
运输条件	超低温冰袋运输
产品介绍	Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC 50 of 0.2 µM. Purpurogallin has antioxidant and anti-inflammatory effects In Vitro Purpurogallin (50 or 100 µM; 7 or 25 hours; BV2 murine microglial cells) treatment attenuates the production of pro-inflammatory cytokines, including interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) by suppressing their mRNA and protein expression in LPS-stimulated BV2 microglial cells. Purpurogallin (100 µM; 75-120 minutes; BV2 murine microglial cells) exhibits anti-inflammatory properties by suppressing the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase signaling pathways in LPS-stimulated BV2 microglial cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. RT-PCRCell Line: BV2 murine microglial cells Concentration: 50 or 100 µM Incubation Time: 7 or 25 hours Result: Attenuated the production of pro-inflammatory cytokines, including interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) by suppressing their mRNA and protein expression. Western Blot AnalysisCell Line: BV2 murine microglial cells Concentration: 100 µM Incubation Time: 75 minutes, 90 minutes, 120 minutes Result: Suppressed the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase signaling pathways. In Vivo Purpurogallin (100-400 μg/kg; intraperitoneal injection; for 48 or 72 hours; male Sprague-Dawley rats) exerts its neuroinflammation effect through the dual effect of inhibiting IL-6 and TNF-α mRNA expression and reducing HMGB1 protein and mRNA expression. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Fifty-four male Sprague-Dawley rats (250-350 g) with subarachnoid hemorrhage (SAH)Dosage: 100 μg/kg, 200 μg/kg, 400 μg/kg Administration: Intraperitoneal injection; for 48 or 72 hours Result: Dose-dependently reduced HMGB1 protein expression. High dose reduced TNF-α and HMGB1 mRNA levels. Form:Solid IC50& Target:IC50: 0.2 µM (xanthine oxidase)
纯度	≥96%

名称和识别符

分子类型	小分子
Smiles	O=C1C(O)=CC=CC2=CC(O)=C(O)C(O)=C21
分子量	220.17

化学和物理性质

溶解性	DMSO : 100 mg/mL (454.17 mM; Need ultrasonic)

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

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找到8个结果

批号(Lot Number)	证书类型	货号
G2501635	分析证书	P649449
G2501636	分析证书	P649449
G2501637	分析证书	P649449
G2501639	分析证书	P649449
G2501640	分析证书	P649449
G2501641	分析证书	P649449
G2501638	分析证书	P649449
G2501642	分析证书	P649449

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红倍酚

库存信息

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基本描述

名称和识别符

化学和物理性质

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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溶液计算器

摩尔浓度计算器

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