PDE9-IN-1

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货号 (SKU)	包装规格	是否现货
P648498-5mg	5mg	期货
P648498-10mg	10mg	期货
P648498-25mg	25mg	期货
P648498-50mg	50mg	期货

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基本描述

别名	PDE9-合一
规格或纯度	≥99%
英文名称	PDE9-IN-1
生化机理	PDE9-IN-1 是一种强效、选择性和口服生物利用型磷酸二酯酶-9A（PDE9A）抑制剂，其 IC 50 为 8.7 nM。
储存温度	-20°C储存
运输条件	超低温冰袋运输
作用类型	抑制剂
产品介绍	PDE9-IN-1 is a potent, selective, and orally bioavailable phosphodiesterase-9A (PDE9A) Inhibitor with an IC 50 of 8.7 nM In Vitro PDE9-IN-1 is excellent selectivity across PDE families. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo PDE9-IN-1 (2.5 and 5.0 mg/kg; Oral administration; daily for 21 days) effectively recovers learning and memory function . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Unilateral common carotid artery occlusion (UCCAO) mouse model Dosage: 2.5 and 5.0 mg/kg Administration: Oral administration; daily for 21 days Result: Significantly reduced the day 6 escape latency time and increased the frequency of platform area crossings, and recovered learning and memory function. High dose group possibly improved the escape latency time of mice. Form:Solid IC50& Target:PDE9A 8.7 nM (IC 50 )
纯度	≥99%