| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| P464992-250mg |
250mg |
期货  |
| |
| P464992-1g |
1g |
期货 |
|
| 英文别名 | Forsythin, Phyllyrin, Phillyroside |
|---|---|
| 规格或纯度 | ≥97% |
| 英文名称 | Phillyrin |
| 储存温度 | 2-8°C储存,充氩 |
| 运输条件 | 冰袋运输 |
| 产品介绍 |
Description Phillyrin is a lignan found in the fruit ofForsythia suspensa. |
| 纯度 | ≥97% |
| 分子类型 | 小分子 |
|---|---|
| Isomeric SMILES | COC1=C(C=C(C=C1)[C@H]2[C@H]3CO[C@@H]([C@H]3CO2)C4=C(C=C(C=C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)OC)OC |
| PubChem CID | 24721571 |
| 分子量 | 534.55 |
| 敏感性 | 对湿度敏感 |
|---|---|
| 分子量 | 534.600 g/mol |
| XLogP3 | 0.800 |
| 氢键供体数Hydrogen Bond Donor Count | 4 |
| 氢键受体数Hydrogen Bond Acceptor Count | 11 |
| 可旋转键计数Rotatable Bond Count | 8 |
| 精确质量Exact Mass | 534.21 Da |
| 单同位素质量Monoisotopic Mass | 534.21 Da |
| 拓扑极表面积Topological Polar Surface Area | 146.000 Ų |
| 重原子数Heavy Atom Count | 38 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 757.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 9 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 信号词 | 警告 |
|---|---|
| 危险声明 |
H302: 吞食有害 H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 |
| 1. Ying Ju, Chunling Yin, Yan Zhang, Xiangru Meng, Liuchuang Zhao, Leqian Hu. (2023) Rapid detection and quality evaluation of Shuang-Huang-Lian injection by ATR-IR and NIR spectroscopy combined with chemometrics. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 286 (122008). [PMID:36283204] [10.1016/j.saa.2022.122008] |
| 2. Xin Guo, Pingping Cao, Xiongfeng Lian, Meng Hu, Jingyi Zhao, Wenjing Shen, Haili Wang, Hailong Yu, Yingzhu Chen. (2021) The neuroprotective effect of phillyrin in intracerebral hemorrhagic mice is produced by activation of the Nrf2 signaling pathway. EUROPEAN JOURNAL OF PHARMACOLOGY, 909 (174439). [PMID:34425100] [10.1016/j.ejphar.2021.174439] |
| 3. Duan Qiong, Li Ruochen, Wang Mingxiao, Cui Zhenting, Zhu Xia, Chen Fanghong, Han Feng, Ma Jianxin. (2024) Exploring the anti-NSCLC mechanism of phillyrin targeting inhibition of the HSP90-AKT pathway. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, (1-14). [PMID:39356318] [10.1007/s00210-024-03481-1] |
| 4. Chenggang Huang, Jiajia Teng, Wei Liu, Junzhe Wang, An Liu. (2024) Modulation of macrophages by a phillyrin-loaded thermosensitive hydrogel promotes skin wound healing in mice. CYTOKINE, 177 (156556). [PMID:38417214] [10.1016/j.cyto.2024.156556] |
| 5. Kaiping Xiang, Bing Wang, Lanying Wang, Yunfei Zhang, Hanzeng Li, Yanping Luo. (2024) Oxidative Stress, Oxidative Damage, and Cell Apoptosis: Toxicity Induced by Arecoline in Caenorhabditis elegans and Screening of Mitigating Agents. Toxins, 16 (8): (352). [PMID:39195762] [10.3390/toxins16080352] |
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