| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| P1496821-1ml |
1ml |
期货  |
|
| 规格或纯度 | Moligand™, 10 mM in DMSO |
|---|---|
| 英文名称 | PCC0208017 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
PCC0208017 is a microtubule affinity regulating kinases ( MARK3/MARK4 ) inhibitor with IC 50 s of 1.8 and 2.01 nM, respectively. PCC0208017 has much lower inhibitory activity against MARK1 and MARK2, with IC 50 s of 31.4 and 33.7 nM, respectively. PCC0208017 suppresses glioma progression in vitro and in vivo. PCC0208017 disrupts microtubule dynamics and induces G2/M phase cell cycle arrest and cell apoptosis . PCC0208017 demonstrates robust antitumor activity in vivo and displays good BBB permeability. |
| 分子量 | 403.40 |
|---|
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