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| 英文名称 | PIN1 degrader-1 |
|---|---|
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 降解剂 |
| 产品介绍 |
PIN1 degrader-1 (Compound 158H9) is the inhibitor for proline cis trans isomerase ( Pin1 ) with an IC 50 of 21.5 nM. PIN1 degrader-1 forms covalent bond with Cys113 of Pin1 , induces conformational changes in Pin1 , reduces its stability, and leads to a proteasome-dependently degradation. PIN1 degrader-1 inhibits the cell viability of multi cancer cells, and can be used in cancer research. |
| 分子量 | 611.52 |
|---|