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1-棕榈酰基-2-油酰基-sn-甘油-3-磷酸胆碱（POPC）

两性离子磷脂
7篇引用文献 COA COA
    级别和纯度:
  • ≥99%
有货

库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
P130452-25mg
 25mg 现货 Stock Image
P130452-100mg
 100mg 现货 Stock Image
P130452-500mg
 500mg 期货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
查看相关系列
Liposome (117) Metabolic Enzyme/Protease (4889) 合成磷脂 (19) 磷脂 (112) 磷脂酰胆碱 (5) 脂质代谢 (4331)
main product photo

基本描述

别名 2-油酰-1-棕榈酰- 锡 -甘油基-3-磷酸胆碱 | 1-十六烷2-(顺式-9-十八碳烯酰基)-sn-甘油-3-磷酸胆碱, 1-棕榈酰-2-油酰-sn-甘油-3-磷酸胆碱, 3-sn-磷脂酰胆碱,2-油酰-1-棕榈酰, L-β-油酰-γ-棕榈酰-α-磷脂, PC(16:0/18:1(9Z)), PC(16:0/18:1), PC(16:0/18:1w9), PC, POPC
英文别名 POPC | PC(16:0/18:1(9Z)) | LMGP01010005 | (R,Z)-2-(Oleoyloxy)-3-(palmitoyloxy)propyl(2-(trimethylammonio)ethyl)phosphate | phosphatidylcholine (1-16:0-2-18:1) | EINECS 218-619-1 | cis-1,2-Dimethylcyclohexane, 99% | Brain PC, L-alpha-phosphatidylcholine (B
规格或纯度 ≥99%
英文名称 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine（POPC）
生化机理 两性离子磷脂。用于脂质双层研究和生物系统。
储存温度 避光,-20°C储存,充氩
运输条件 超低温冰袋运输
备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍

POPC is typically considered one of the model lipids for biophysical experiments. The fatty acid composition, i.e., saturated chain in the sn-1 position and unsaturated chain in the sn-2 position, mimics mammalian phospholipid composition. Since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC, POPC is an excellent synthetic substitute for EPC.The effect of non-ionic detergent on liposomes was studied with giant POPC liposomes. Increasing concentrations of detergent cause tubular protrusions, then indentations, to develop on spherical liposomes. At higher detergent concentrations, the liposomes burst.

POPC is typically considered one of the model lipids for biophysical experiments. The fatty acid composition, i.e., saturated chain in the sn-1 position and unsaturated chain in the sn-2 position, mimics mammalian phospholipid composition. Since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC, POPC is an excellent synthetic substitute for EPC.
The effect of non-ionic detergent on liposomes was studied with giant POPC liposomes. Increasing concentrations of detergent cause tubular protrusions, then indentations, to develop on spherical liposomes. At higher detergent concentrations, the liposomes burst.
纯度 ≥99%

名称和识别符

EC号 248-056-7
分子类型 小分子
IIUPAC Name [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
INCHI 1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
InChi Key WTJKGGKOPKCXLL-VYOBOKEXSA-N
Smiles CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC
Isomeric SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCC/C=C\CCCCCCCC
关联CAS 59491-62-2
分子量 760.08
Beilstein号 4173237
Reaxy-Rn 4173236
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4173236&ln=

化学和物理性质

溶解性 Chloroform (Slightly), Methanol (Slightly)
敏感性 对光线敏感；对湿度敏感；对空气敏感
分子量 760.100 g/mol
XLogP3 13.600
氢键供体数Hydrogen Bond Donor Count 0
氢键受体数Hydrogen Bond Acceptor Count 8
可旋转键计数Rotatable Bond Count 41
精确质量Exact Mass 759.578 Da
单同位素质量Monoisotopic Mass 759.578 Da
拓扑极表面积Topological Polar Surface Area 111.000 Ų
重原子数Heavy Atom Count 52
形式电荷Formal Charge 0
复杂度Complexity 899.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 1
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 1
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 1
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

WGK Germany 3
个人防护装备 Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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批号(Lot Number) 证书类型 货号
F2519764 分析证书 P130452
F2519766 分析证书 P130452
G2426320 分析证书 P130452
G2426333 分析证书 P130452
E2410500 分析证书 P130452
D2521351 分析证书 P130452
F2519724 分析证书 P130452
D2521375 分析证书 P130452
D2521447 分析证书 P130452
L2412200 分析证书 P130452
G2426351 分析证书 P130452
G2426319 分析证书 P130452
D2426046 分析证书 P130452
J2323647 分析证书 P130452
J2323646 分析证书 P130452
I2207144 分析证书 P130452
F2117212 分析证书 P130452
L2103012 分析证书 P130452
L2103014 分析证书 P130452
I2207145 分析证书 P130452
I2207147 分析证书 P130452

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可替换产品

  1. 1-棕榈酰基-2-油酰基-sn-甘油-3-磷酸胆碱 (POPC)
    1-棕榈酰基-2-油酰基-sn-甘油-3-磷酸胆碱 (POPC)
    • ≥98%

    ¥205.90

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引用文献

1. He Li, Yue Yan, Jing Chen, Ke Shi, Chuwen Song, Yanglimin Ji, Liyan Jia, Jianming Li, Yan Qiao, Yiyang Lin.  (2023)  Artificial receptor-mediated phototransduction toward protocellular subcompartmentalization and signaling-encoded logic gates.  Science Advances,  9  (9): [PMID:36857444] [10.1126/sciadv.ade5853]
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3. Minglei Chen, Kambere Amerigos Daddy J.C., Zhigui Su, Nida El Islem Guissi, Yanyu Xiao, Li Zong, Qineng Ping.  (2019)  Folate Receptor-Targeting and Reactive Oxygen Species-Responsive Liposomal Formulation of Methotrexate for Treatment of Rheumatoid Arthritis.  Pharmaceutics,  11  (11): (582).  [PMID:31698794] [10.3390/pharmaceutics11110582]
4. Chuanye Tang, Lei Feng, Pinghua Ling, Qiuting Wang, Wenwen Xu, Danjie Song, Yalong Qiao, Feng Gao.  (2025)  DNA Logic Gate-Triggered Membrane Fusion for Accurately Detecting and Killing Cancer Cells.  ACS Applied Materials & Interfaces,  17  (7): (10446-10456).  [PMID:39907089] [10.1021/acsami.4c20737]
5. Jinlei Yang, Jing Wang, Runsong Cheng, Tianyi Liao, Siyuan Pan, Murong Du, Weiliang Liu, Liying Yan, Sichun Zhang, Xinrong Zhang.  (2025)  Microseparation of Lipophilic and Hydrophilic Metabolites for Single Oocyte Mass Spectrometry Analysis.  ANALYTICAL CHEMISTRY,  [PMID:39800910] [10.1021/acs.analchem.4c04900]
6. Zhirong Li, Lulu Zhang, Zhanzhong Wang, Xiongli Kang, Huiying Jin, Wenjie Zhao, Jun Zhang, Haiquan Su.  (2024)  Quantification of Phosphatidylserine Molecules on the Surface of Individual Cells Using Single-Molecule Force Spectroscopy.  ANALYTICAL CHEMISTRY,  96  (2): (676-684).  [PMID:38173079] [10.1021/acs.analchem.3c03517]
7. Yalong Qiao, Linyu Wang, Wenwen Xu, Pei Yang, Chuanye Tang, Danjie Song, Pinghua Ling, Feng Gao.  (2024)  Reversible Modulation of Cell–Cell Interactions Using Electrochemistry.  ACS Applied Materials & Interfaces,  16  (33): (43341-43349).  [PMID:39103300] [10.1021/acsami.4c08619]

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