| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| O1496146-1ml |
1ml |
期货  |
|
| 规格或纯度 | Moligand™, 10 mM in DMSO |
|---|---|
| 英文名称 | ONX-0914 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
ONX-0914 (PR-957) is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7) , the chymotrypsin-like subunit of the immunoproteasome. ONX-0914 blocks cytokine production and attenuates progression of experimental arthritis. ONX-0914 is a noncompetitive irreversible inhibitor of the mycobacterial proteasome (K i =5.2 μM). ONX-0914 reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1. |
| Isomeric SMILES | C[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)OC)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)[C@]3(CO3)C)NC(=O)CN4CCOCC4 |
|---|---|
| MeSH Entry Terms | (S)-3-(4-methoxyphenyl)-N-((S)-1-((S)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)propanamido)propanamide;ONX 0914;PR-957 |
| 分子量 | 580.67 |
| Reaxy-Rn | 34060250 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=34060250&ln= |
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