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基本描述
| 英文名称 | O-7460 |
|---|---|
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 产品介绍 |
O-7460 is a potent and selective DAGLα inhibitor, with an IC 50 of 0.69 μM. O-7460 shows selectivity over onoacylglycerol lipase ( MAGL ), human CB1 and CB2 cannabinoid receptors. O-7460 can decrease HFD-caused an up-regulation of 2-AG levels. |
名称和识别符
| IIUPAC Name | [1-[fluoro(methyl)phosphoryl]oxy-3-propan-2-yloxypropan-2-yl] (Z)-octadec-9-enoate |
|---|---|
| INCHI | 1S/C25H48FO5P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-25(27)31-24(21-29-23(2)3)22-30-32(4,26)28/h12-13,23-24H,5-11,14-22H2,1-4H3/b13-12- |
| InChi Key | ZLEFMXNNQCABDB-SEYXRHQNSA-N |
| Smiles | CCCCCCCCC=CCCCCCCCC(=O)OC(COC(C)C)COP(=O)(C)F |
| Isomeric SMILES | CCCCCCCC/C=C\CCCCCCCC(=O)OC(COC(C)C)COP(=O)(C)F |
| PubChem CID | 132285144 |
| 分子量 | 463.74 |
质检证书（CoA,COO,BSE/TSE 和分析图谱)
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