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丁酰胆碱酯酶 来源于人血浆

  • Accession #: P06276
  • 生物活性: ≥50 U/mg protein
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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
np001121-2U
2U 期货 Stock Image
np001121-10U
10U 期货 Stock Image

基本描述

产品名称 丁酰胆碱酯酶 来源于人血浆
别名 Acylcholine acylhydrolase, BChE | 假性胆碱酯酶 | 胆碱酯酶 | 丁酰基 | 酰基胆碱酰基水解酶
英文别名 Acylcholine acylhydrolase | BChE
规格或纯度 ActiBioPure™, 生物活性, 高性能, EnzymoPure™, ≥90%(SDS-PAGE), Pre-lyophilization Protein Concentration
生化机理 Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters. Post-translational: N-glycosylated. No other PTM detected. The major N-glycan structures are of the complex diantennary type with 1 and 2 N-acetylneuraminic acid molecules (Neu5Ac) making up approximately 33% and 47% of the total N-glycans, respectively. Only low amounts of fucosylated diantennary N-glycans are detected (approximately 2%). Triantennary N-glycans with or without fucose amount to approximately 13%, whereas 5% of the total N-glycans are of the oligomannosidic or hybrid type.
产品介绍

 

Butyrylcholinesterase (BChE) is a tetrameric glycoprotein belonging to the family of serine hydrolases known as cholinesterases. While there is currently no know physiological function for BChE, it has been shown to behave as a bioscavenger against cocaine toxicity and organophosphorus nerve agents.

Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.

生物活性 ≥50 U/mg protein
种属 人(Human)
Accession # P06276
来源 天然
预测分子量 340 kDa

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from 100 mM L-Histidine, 240 mM sucrose, 0.3 mM TWEEN 20, pH 6.0
浓度 Pre-lyophilization Protein Concentration
复溶 After centrifugation, we suggest addition of de-ionized H2O to the original volume (See COA), followed by gentle mixing to ensure adequate homogenization.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 长期储存-20℃(大于1年);复溶后建议分装,避免反复冻融。
CAS编号和信息 9001-08-5
酶学委员会编号 3.1.1.8
单位定义 One unit will hydrolyze one micromole of butyrylcholine to choline and butyrate per minute at pH 8.0 at 37℃.
分子类型

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批号(Lot Number) 证书类型 货号
ZJ25F0926568 分析证书 np001121

技术文档和文章

此产品的引用文献

引用文献

1. Zhenpeng Men, Ragini Singh, Bingyuan Zhang, Santosh Kumar.  (2025)  Seven-Core Tapered Optical Fiber LSPR Biosensor with CMC Structure for Ultra-Sensitive Detection of Paraoxon in Environmental Monitoring.  IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,  74  (1-1).  [10.1109/TIM.2025.3552480]

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