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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| np001121-2U |
2U |
期货 ![]() |
| |
| np001121-10U |
10U |
期货 ![]() |
|
| 产品名称 | 丁酰胆碱酯酶 来源于人血浆 |
|---|---|
| 别名 | Acylcholine acylhydrolase, BChE | 假性胆碱酯酶 | 胆碱酯酶 | 丁酰基 | 酰基胆碱酰基水解酶 |
| 英文别名 | Acylcholine acylhydrolase | BChE |
| 规格或纯度 | ActiBioPure™, 生物活性, 高性能, EnzymoPure™, ≥90%(SDS-PAGE), Pre-lyophilization Protein Concentration |
| 生化机理 | Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters. Post-translational: N-glycosylated. No other PTM detected. The major N-glycan structures are of the complex diantennary type with 1 and 2 N-acetylneuraminic acid molecules (Neu5Ac) making up approximately 33% and 47% of the total N-glycans, respectively. Only low amounts of fucosylated diantennary N-glycans are detected (approximately 2%). Triantennary N-glycans with or without fucose amount to approximately 13%, whereas 5% of the total N-glycans are of the oligomannosidic or hybrid type. |
| 产品介绍 |
Butyrylcholinesterase (BChE) is a tetrameric glycoprotein belonging to the family of serine hydrolases known as cholinesterases. While there is currently no know physiological function for BChE, it has been shown to behave as a bioscavenger against cocaine toxicity and organophosphorus nerve agents. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests. |
| 生物活性 | ≥50 U/mg protein |
| 种属 | 人(Human) |
| Accession # | P06276 |
| 来源 | 天然 |
| 预测分子量 | 340 kDa |
| 物理形态 | 冻干(Lyophilized) |
|---|---|
| 储存缓冲液 | Lyophilized from 100 mM L-Histidine, 240 mM sucrose, 0.3 mM TWEEN 20, pH 6.0 |
| 浓度 | Pre-lyophilization Protein Concentration |
| 复溶 | After centrifugation, we suggest addition of de-ionized H2O to the original volume (See COA), followed by gentle mixing to ensure adequate homogenization. |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 长期储存-20℃(大于1年);复溶后建议分装,避免反复冻融。 |
| CAS编号和信息 | 9001-08-5 |
| 酶学委员会编号 | 3.1.1.8 |
| 单位定义 | One unit will hydrolyze one micromole of butyrylcholine to choline and butyrate per minute at pH 8.0 at 37℃. |
| 分子类型 | 酶 |
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | np001121 |
| 1. Zhenpeng Men, Ragini Singh, Bingyuan Zhang, Santosh Kumar. (2025) Seven-Core Tapered Optical Fiber LSPR Biosensor with CMC Structure for Ultra-Sensitive Detection of Paraoxon in Environmental Monitoring. IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, 74 (1-1). [10.1109/TIM.2025.3552480] |