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组织蛋白酶B,人肝

    级别和纯度:
  • ≥95%(SDS-PAGE)
  • Extinction Coefficient: 2.0
  • Accession #: P07858
有货

库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
np001112-10μg
10μg 期货 Stock Image
np001112-25μg
25μg 期货 Stock Image

基本描述

产品名称 组织蛋白酶B,人肝
规格或纯度 ≥95%(SDS-PAGE), Extinction Coefficient: 2.0
产品介绍

组织蛋白酶B是一种半胱氨酸蛋白酶,位于溶酶体中,参与组织降解和重组。具体而言,组织蛋白酶B被认为参与内吞作用吸收的细胞外蛋白质的细胞内消化。

Cathepsin B, a cysteine proteinase, is located in lysosomes and is involved in tissue degradation and restructuring. Specifically, cathepsin B is believed to be involved in the intracellular digestion of extracellular proteins taken up by endocytosis.

Ref: Rich D.H., Brown M.A. and Barrett A.J. 1986 Biochem J, 235, 731-734.

Product Citations:
Armstrong, Andrea, Niklas Mattsson, Hanna Appelqvist, Camilla Janefjord, Linnea Sandin, Lotta Agholme, Bob Olsson et al. "Lysosomal Network Proteins as Potential Novel CSF Biomarkers for Alzheimer’s Disease."Neuromolecular medicine 16, no. 1 (2014): 150-160.
Watson, Andre, Cara Yocum, Vaibhav Pandit, and Shiva P. Kotha. "Optimizing Polymeric Nanoparticle Core Designs for Gene Delivery." In Bioengineering Conference (NEBEC), 2013 39th Annual Northeast, pp. 1-2. IEEE, 2013.
Toneff, Thomas, Lydiane Funkelstein, Charles Mosier, Armen Abagyan, Michael Ziegler, and Vivian Hook. "Beta-Amyloid Peptides Undergo Regulated Co-Secretion with Neuropeptide and Catecholamine Neurotransmitters."Peptides (2013).
Elie, Benelita Tina, Vasilena Gocheva, Tanaya Shree, Stacie A. Dalrymple, Leslie J. Holsinger, and Johanna A. Joyce. "Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model." Biochimie 92, no. 11 (2010): 1618-1624.

Accession # P07858
预测分子量 27500

储存与运输

储存缓冲液 50 mM Na Acetate, pH 5.0 with 1mM EDTA
浓度 Extinction Coefficient: 2.0
储存温度 -80℃储存
运输条件 超低温冰袋运输
单位定义 ≥ 200 units/mg protein. One unit is defined as the amount of enzyme that hydrolyzes one umole of Z-Arg-Arg-beta-naphthylamide per minute at 40oC, using 100 mM Na/K phosphate, pH 6.0, with 1.33 mM EDTA and 2 mM DTT as the activation buffer.

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

技术文档和文章

溶液计算器