NG-497

级别和纯度:

有货

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货号 (SKU)	包装规格	是否现货
N649972-5mg	5mg	期货
N649972-10mg	10mg	期货
N649972-25mg	25mg	期货
N649972-50mg	50mg	期货
N649972-100mg	100mg	期货

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ATGL (4) Metabolic Enzyme/Protease (4889) 脂质代谢 (4331)

基本描述

规格或纯度	≥98%
英文名称	NG-497
生化机理	NG-497 是一种选择性人脂肪甘油三酯脂酶（ATGL）抑制剂，其靶标是具有酶活性的人 ATGL 蛋白样结构域。NG-497 具有潜在的肿瘤研究价值。
储存温度	2-8°C储存,避光,干燥
运输条件	冰袋运输
作用类型	抑制剂
产品介绍	NG-497 is a selective human adipose triglyceride lipase ( ATGL ) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research. In Vitro NG-497 selectively inactivates human and nonhuman primate ATGL but not structurally and functionally related lipid hydrolases and abolishes human adipocytes in a dose-dependent and reversible manner Lipolysis. NG-497 (40 μM, 80 min) reduces lipolysis-dependent respiration in HepG2 cells without impairing mitochondrial function through off-target effects. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
纯度	≥98%