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Niclosamide-13C6

    级别和纯度:
  • ≥99%
  • CAS编号: 1325808-64-7
  • 分子式: C713C6H8Cl2N2O4
  • 分子量: 333.08
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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
N647673-5mg
5mg 期货 Stock Image
N647673-10mg
10mg 期货 Stock Image

基本描述

别名 氯硝柳胺-13C6
规格或纯度 ≥99%
英文名称 Niclosamide-13C6
生化机理 Niclosamide- 13 C 6 是标记为 13 C 6 的氯硝柳胺。Niclosamide (BAY2353)xa0 是一种口服生物可用的氯化水杨酰苯胺,具有驱虫和潜在的抗肿瘤活性。烟酰胺(BAY2353)对 STAT3 的抑制作用在 HeLa 细胞中的 IC50 为 0.25 μM。
储存温度 -20°C储存
运输条件 超低温冰袋运输
产品介绍


Niclosamide- 13 C 6 is the 13 C 6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

纯度 ≥99%

名称和识别符

Smiles O=C(N[13C]1=[13CH][13CH]=[13C]([N+]([O-])=O)[13CH]=[13C]1Cl)C2=CC(Cl)=CC=C2O
分子量 333.08

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