| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| N130612-5mg |
5mg |
现货  |
|
| 别名 | N-二十二烷酰-D-赤-鞘氨醇 |
|---|---|
| 英文别名 | C22 Ceramide (d18:1/22:0), N-behenoyl-D-erythro-sphingosine, powder | Ceramide d40:1 | N-(docosanoyl) sphingosine | N-[1.3-dihydroxyoctadec-4-en-2-yl]docosanamide | N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]docosanamide | C22 Ceramide (d18:1/22:0) | Ce |
| 规格或纯度 | ≥99% |
| 英文名称 | C22 Ceramide (d18:1/22:0) |
| 生化机理 | 神经酰胺在调节细胞分化、增殖和凋亡方面发挥着重要作用。它还能调节应激反应和炎症 |
| 应用 | C22 Ceramide (d18:1/22:0) has been used: · as a standard to measure ceramide concentrations in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (LC/MS2） · as a standard for the quantitation of sphingolipid metabolites · to study its effects on mitochondrial-to-cytosolic stress response (MCSR) induction |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
C22 Ceramide (d18:1/22:0) or N-behenoyl-D-erythro-sphingosine is a synthetic ceramide containing sphingosine with behenic acid C22 Ceramide (d18:1/22:0) has been used: • as a standard to measure ceramide concentrations in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (LC/MS2） • as a standard for the quantitation of sphingolipid metabolites • to study its effects on mitochondrial-to-cytosolic stress response (MCSR) induction C22 Ceramide (d18:1/22:0) or N-behenoyl-D-erythro-sphingosine is a synthetic ceramide containing sphingosine with behenic acid C22 Ceramide (d18:1/22:0) has been used: • as a standard to measure ceramide concentrations in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (LC/MS2） • as a standard for the quantitation of sphingolipid metabolites • to study its effects on mitochondrial-to-cytosolic stress response (MCSR) induction |
| 纯度 | ≥99% |
| PubChem SID | 504763471 |
|---|---|
| IIUPAC Name | N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]docosanamide |
| INCHI | 1S/C40H79NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-24-26-28-30-32-34-36-40(44)41-38(37-42)39(43)35-33-31-29-27-25-23-16-14-12-10-8-6-4-2/h33,35,38-39,42-43H,3-32,34,36-37H2,1-2H3,(H,41,44)/b35-33+/t38-,39+/m0/s1 |
| InChi Key | KEPQASGDXIEOIL-GLQCRSEXSA-N |
| Smiles | CCCCCCCCCCCCCCCCCCCCCC(=O)NC(CO)C(C=CCCCCCCCCCCCCC)O |
| Isomeric SMILES | CCCCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@@H](/C=C/CCCCCCCCCCCCC)O |
| 分子量 | 622.06 |
| Reaxy-Rn | 54814198 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=54814198&ln= |
| 分子量 | 622.100 g/mol |
|---|---|
| XLogP3 | 16.100 |
| 氢键供体数Hydrogen Bond Donor Count | 3 |
| 氢键受体数Hydrogen Bond Acceptor Count | 3 |
| 可旋转键计数Rotatable Bond Count | 36 |
| 精确质量Exact Mass | 621.606 Da |
| 单同位素质量Monoisotopic Mass | 621.606 Da |
| 拓扑极表面积Topological Polar Surface Area | 69.600 Ų |
| 重原子数Heavy Atom Count | 44 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 593.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 2 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 1 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 1 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
¥647.90
¥2,264.90
| 1. Jie Zhang, Xiaoling Zang, Peng Jiao, Jiangyu Wu, Wei Meng, Lizhen Zhao, Zhihua Lv. (2024) Alterations of Ceramides, Acylcarnitines, GlyceroLPLs, and Amines in NSCLC Tissues. JOURNAL OF PROTEOME RESEARCH, 23 (10): (4343-4358). [PMID:39317643] [10.1021/acs.jproteome.4c00344] |
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