L-正亮氨酸

4篇引用文献

COA

级别和纯度:

≥99%

CAS编号: 327-57-1
分子式: C₆H₁₃NO₂
分子量: 131.17
Beilstein号: 1721750
EC号: 206-321-4
MDL号: MFCD00064423
PubChem编号: 21236
PubChem SID: 488182679

有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭

货号 (SKU)	包装规格	是否现货
N109230-1g	1g	现货
N109230-5g	5g	现货
N109230-25g	25g	现货
N109230-100g	100g	现货
N109230-500g	500g	期货

查看相关系列

Anti-infection (2804) Influenza Virus (253) Virus (3767) 代谢物 (8911) 化学生物学 (1256) 肽化学 (316)

Skip to the end of the images gallery

Skip to the beginning of the images gallery

基本描述

别名	L-2-氨基己酸 \| (S)-2-氨基己酸 \| (S)-(+)-2-氨基己酸 \| L-(+)-己氨酸
英文别名	n-C4H9CH(NH2)COOH \| (2S)-2-aminohexanoic acid \| 2-Aminocaproate \| Glycoleucine \| (S)-2-aminohexanoate \| (S)-2-amino-Hexanoate \| AKOS006240047 \| BRN 1721750 \| .alpha.-Aminocaproic acid \| Caprine \| UNII-832C8OV84S \| Hexanoic acid, 2-amino-, (S)- \| M03242 \|
规格或纯度	≥99%
英文名称	L-Norleucine
生化机理	L-正亮氨酸是一种通常用作内标的合成氨基酸。
运输条件	常规运输
纯度	≥99%

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	488182679
EC号	206-321-4
分子类型	小分子
IIUPAC Name	(2S)-2-aminohexanoic acid
INCHI	1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
InChi Key	LRQKBLKVPFOOQJ-YFKPBYRVSA-N
Smiles	CCCCC(C(=O)O)N
Isomeric SMILES	CCCC[C@@H](C(=O)O)N
分子量	131.17
Beilstein号	1721750
Reaxy-Rn	1721748
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1721748&ln=

化学和物理性质

溶解性	souble in water
密度	1.038
比旋光度	23 ° (C=5, 5mol/L HCl)
熔点	300°C
分子量	131.170 g/mol
XLogP3	-1.500
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	3
可旋转键计数Rotatable Bond Count	4
精确质量Exact Mass	131.095 Da
单同位素质量Monoisotopic Mass	131.095 Da
拓扑极表面积Topological Polar Surface Area	63.300 Å²
重原子数Heavy Atom Count	9
形式电荷Formal Charge	0
复杂度Complexity	93.100
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS07
信号词	警告
危险声明	H317: 可能引起皮肤过敏反应
预防措施声明	P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P272: 被污染的工作服不允许离开工作场所 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P333+P313: 如发生皮肤刺激或皮疹：求医/就诊。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P501: 将内容物/容器处理到。。。
WGK Germany	3
RTECS	RC6308000
Merck Index	6706
个人防护装备	dust mask type N95 (US),Eyeshields,Faceshields,Gloves

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到11个结果

批号(Lot Number)	证书类型	货号
L2108625	分析证书	N109230
L2108626	分析证书	N109230
L2108641	分析证书	N109230
H2130248	分析证书	N109230
H2130250	分析证书	N109230
C23211091	分析证书	N109230
I2519022	分析证书	N109230
D1810179	分析证书	N109230
D2321401	分析证书	N109230
I2423656	分析证书	N109230
H2130247	分析证书	N109230

显示更多⌵

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站? 引用文献检索

引用文献

1. Geissler S, Hellwig M, Zwarg M, Markwardt F, Henle T, Brandsch M. (2010) Transport of the advanced glycation end products alanylpyrraline and pyrralylalanine by the human proton-coupled peptide transporter hPEPT1.. J Agric Food Chem, 58 (4): (2543-7). [PMID:20104847]
2. Kevin Guo,Liang Li. (2009-03-25) Differential 12C-/13C-isotope dansylation labeling and fast liquid chromatography/mass spectrometry for absolute and relative quantification of the metabolome.. Analytical chemistry, 81 ((10)): (3919-3932). [PMID:19309105]
3. Petros Chatzigeorgiou,Nikos Papakonstantopoulos,Nikolitsa Tagaroulia,Evangelos Pollatos,Pantelis Xynogalas,Kyriakos Viras. (2010-01-02) Solid-solid phase transitions in DL-norvaline studied by differential scanning calorimetry and Raman spectroscopy.. The journal of physical chemistry. B, 114 ((3)): (1294-1300). [PMID:20043648]
4. Francesco Misiti,M Elisabetta Clementi,Bruno Giardina. (2010-01-12) Oxidation of methionine 35 reduces toxicity of the amyloid beta-peptide(1-42) in neuroblastoma cells (IMR-32) via enzyme methionine sulfoxide reductase A expression and function.. Neurochemistry international, 56 ((4)): (597-602). [PMID:20060866]
5. Jan Pícha,Miloš Buděšínský,Pavel Fiedler,Miloslav Sanda,Jiří Jiráček. (2010-03-30) Synthesis of α-carboxyphosphinopeptides derived from norleucine.. Amino acids, 39 ((5)): (1265-1280). [PMID:20349321]
6. Silvia Lisa,Massimiliano Meli,Gema Cabello,Ruth Gabizon,Giorgio Colombo,María Gasset. (2010-05-11) The structural intolerance of the PrP alpha-fold for polar substitution of the helix-3 methionines.. Cellular and molecular life sciences : CMLS, 67 ((16)): (2825-2838). [PMID:20454997]
7. Jeffery Escobar,Jason W Frank,Agus Suryawan,Hanh V Nguyen,Cynthia G Van Horn,Susan M Hutson,Teresa A Davis. (2010-06-11) Leucine and alpha-ketoisocaproic acid, but not norleucine, stimulate skeletal muscle protein synthesis in neonatal pigs.. The Journal of nutrition, 140 ((8)): (1418-1424). [PMID:20534881]
8. Haiyan Wei,Lijiang Yang,Yi Qin Gao. (2010-08-24) Mutation of charged residues to neutral ones accelerates urea denaturation of HP-35.. The journal of physical chemistry. B, 114 ((36)): (11820-11826). [PMID:20726545]
9. Sarah E Crider,Robert J Holbrook,Katherine J Franz. (2010-11-13) Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1.. Metallomics : integrated biometal science, 2 ((1)): (74-83). [PMID:21072377]
10. Yu-Ying Yang,Markus Grammel,Anuradha S Raghavan,Guillaume Charron,Howard C Hang. (2010-11-26) Comparative analysis of cleavable azobenzene-based affinity tags for bioorthogonal chemical proteomics.. Chemistry & biology, 17 ((11)): (1212-1222). [PMID:21095571]
11. Stefanie Geissler,Michael Hellwig,Fritz Markwardt,Thomas Henle,Matthias Brandsch. (2011-01-11) Synthesis and intestinal transport of the iron chelator maltosine in free and dipeptide form.. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 78 ((1)): (75-82). [PMID:21216287]
12. Troy Cellmer,Marco Buscaglia,Eric R Henry,James Hofrichter,William A Eaton. (2011-03-29) Making connections between ultrafast protein folding kinetics and molecular dynamics simulations.. Proceedings of the National Academy of Sciences of the United States of America, 108 ((15)): (6103-6108). [PMID:21441105]
13. William J Zinnanti,Jelena Lazovic. (2011-05-05) Interrupting the mechanisms of brain injury in a model of maple syrup urine disease encephalopathy.. Journal of inherited metabolic disease, 35 ((1)): (71-79). [PMID:21541722]
14. Diya M Abdeljabbar,Thomas J Klein,A James Link. (2011-06-15) An engineered methionyl-tRNA synthetase enables azidonorleucine incorporation in methionine prototrophic bacteria.. Chembiochem : a European journal of chemical biology, 12 ((11)): (1699-1702). [PMID:21671329]
15. Stephanie N Dupuis,Thomas Veinot,Susan M A Monro,Susan E Douglas,Raymond T Syvitski,Kerry B Goralski,Sherri A McFarland,David L Jakeman. (2011-11-05) Jadomycins derived from the assimilation and incorporation of norvaline and norleucine.. Journal of natural products, 74 ((11)): (2420-2424). [PMID:22050382]
16. Divi Cornec,Adrian Tempescul,Solène Querellou,Pascal Hutin,Jacques-Olivier Pers,Christophe Jamin,Boutahar Bendaoud,Christian Berthou,Yves Renaudineau,Pierre Youinou. (2011-11-16) Identification of patients with indolent B cell lymphoma sensitive to rituximab monotherapy.. Annals of hematology, 91 ((5)): (715-721). [PMID:22083514]
17. Eleftherios P Paschalis. (2011-12-02) Fourier transform infrared imaging of bone.. Methods in molecular biology (Clifton, N.J.), 816 (517-525). [PMID:22130948]
18. Makoto Hibi,Takashi Kawashima,Pavel M Sokolov,Sergey V Smirnov,Tomohiro Kodera,Masakazu Sugiyama,Sakayu Shimizu,Kenzo Yokozeki,Jun Ogawa. (2012-05-16) L-leucine 5-hydroxylase of Nostoc punctiforme is a novel type of Fe(II)/α-ketoglutarate-dependent dioxygenase that is useful as a biocatalyst.. Applied microbiology and biotechnology, 97 ((6)): (2467-2472). [PMID:22584432]
19. Amar R Mohite,Ramakrishna G Bhat. (2012-05-24) Enantiopure synthesis of side chain-modified α-amino acids and 5-cis-alkylprolines.. The Journal of organic chemistry, 77 ((12)): (5423-5428). [PMID:22616793]
20. Michael Biermann,Bettina Bardl,Sebastian Vollstädt,Julia Linnemann,Uwe Knüpfer,Guido Seidel,Uwe Horn. (2013-01-12) Simultaneous analysis of the non-canonical amino acids norleucine and norvaline in biopharmaceutical-related fermentation processes by a new ultra-high performance liquid chromatography approach.. Amino acids, 44 ((4)): (1225-1231). [PMID:23306451]
21. Alborz Mahdavi,Janek Szychowski,John T Ngo,Michael J Sweredoski,Robert L J Graham,Sonja Hess,Olaf Schneewind,Sarkis K Mazmanian,David A Tirrell. (2013-12-19) Identification of secreted bacterial proteins by noncanonical amino acid tagging.. Proceedings of the National Academy of Sciences of the United States of America, 111 ((1)): (433-438). [PMID:24347637]
22. Shuying Huo,Jingran Dong,Shigang Shen,Yanli Ren,Changying Song,Jianzhong Xu,Tiesheng Shi. (2014-07-31) L-selenomethionine reduces platinum(IV) anticancer model compounds at strikingly faster rates than L-methionine.. Dalton transactions (Cambridge, England : 2003), 43 ((41)): (15328-15336). [PMID:25075569]
23. Danique van Vliet,Karen Anjema,Rianne Jahja,Martijn J de Groot,Geertje B Liemburg,M Rebecca Heiner-Fokkema,Eddy A van der Zee,Terry G J Derks,Ido P Kema,Francjan J van Spronsen. (2014-12-04) BH4 treatment in BH4-responsive PKU patients: preliminary data on blood prolactin concentrations suggest increased cerebral dopamine concentrations.. Molecular genetics and metabolism, 114 ((1)): (29-33). [PMID:25466353]
24. Mark C Wesley,Luis M Pereira,Laurie A Scharp,Sitaram M Emani,Francis X McGowan,James A DiNardo. (2015-01-15) Pharmacokinetics of tranexamic acid in neonates, infants, and children undergoing cardiac surgery with cardiopulmonary bypass.. Anesthesiology, 122 ((4)): (746-758). [PMID:25585004]
25. Ma Paz Lorenzo,Danuta Dudzik,Elena Varas,Manuel Gibellini,Mariusz Skotnicki,Marcin Zorawski,Wieslaw Zarzycki,Federica Pellati,Antonia García. (2015-02-14) Optimization and validation of a chiral GC-MS method for the determination of free D-amino acids ratio in human urine: application to a gestational diabetes mellitus study.. Journal of pharmaceutical and biomedical analysis, 107 (480-487). [PMID:25679092]
26. Izabela Domitrz,Marek D Koter,Malgorzata Cholojczyk,Wojciech Domitrz,Anna Baranczyk-Kuzma,Anna Kaminska. (2015-02-26) Changes in Serum Amino Acids in Migraine Patients without and with Aura and their Possible Usefulness in the Study of Migraine Pathogenesis.. CNS & neurological disorders drug targets, 14 ((3)): (345-349). [PMID:25714963]
27. Chang-Feng Chi,Fa-Yuan Hu,Bin Wang,Zhong-Rui Li,Hong-Yu Luo. (2015-04-30) Influence of Amino Acid Compositions and Peptide Profiles on Antioxidant Capacities of Two Protein Hydrolysates from Skipjack Tuna (Katsuwonus pelamis) Dark Muscle.. Marine drugs, 13 ((5)): (2580-2601). [PMID:25923316]
28. Monika Gibis,Jochen Weiss. (2015-10-08) Impact of Precursors Creatine, Creatinine, and Glucose on the Formation of Heterocyclic Aromatic Amines in Grilled Patties of Various Animal Species.. Journal of food science, 80 ((11)): (C2430-C2439). [PMID:26445401]
29. Luana Bontempo,Katryna A van Leeuwen,Mauro Paolini,Kristian Holst Laursen,Cristina Micheloni,Paul D Prenzler,Danielle Ryan,Federica Camin. (2020-03-07) Bulk and compound-specific stable isotope ratio analysis for authenticity testing of organically grown tomatoes.. Food chemistry, 318 (126426-126426). [PMID:32135420]
30. Jan Pícha,Radek Liboska,Miloš Buděšínský,Jiři Jiráček,Małgorzata Pawełczak,Artur Mucha. (2010-06-29) Unusual activity pattern of leucine aminopeptidase inhibitors based on phosphorus containing derivatives of methionine and norleucine.. Journal of enzyme inhibition and medicinal chemistry, 26 ((2)): (155-161). [PMID:20578976]
31. Mikel L Olson,Ian J Cero. (2010-09-08) Intrahippocampal Norleucine¹-Angiotensin IV mitigates scopolamine-induced spatial working memory deficits.. Peptides, 31 ((12)): (2209-2215). [PMID:20816712]
32. James A Van Deventer,John D Fisk,David A Tirrell. (2011-03-16) Homoisoleucine: a translationally active leucine surrogate of expanded hydrophobic surface area.. Chembiochem : a European journal of chemical biology, 12 ((5)): (700-702). [PMID:21404412]
33. Everton F Lima,Franklin Riet-Correa,Dale R Gardner,Severo S Barros,Rosane M T Medeiros,Mauro P Soares,Gabriela Riet-Correa. (2012-05-09) Poisoning by Indigofera lespedezioides in horses.. Toxicon : official journal of the International Society on Toxinology, 60 ((3)): (324-328). [PMID:22560887]
34. Samy Boulos,Anina Tännler,Laura Nyström. (2020-08-06) Nitrogen-to-Protein Conversion Factors for Edible Insects on the Swiss Market: T. molitor, A. domesticus, and L. migratoria.. Frontiers in nutrition, 7 (89-89). [PMID:32754611]
35. Lu Gao, Jia-Hua Zhang, Xiao-Xu Chen, Hui-Li Ren, Xiu-Ling Feng, Jia-Ling Wang, Jun-Hua Xiao. (2019) Combination of L-Arginine and L-Norvaline protects against pulmonary fibrosis progression induced by bleomycin in mice. BIOMEDICINE & PHARMACOTHERAPY, 113 (108768). [PMID:30889486] [10.1016/j.biopha.2019.108768]
36. Qing Xiong, Jing Jin, Liqiong Lv, Zhisi Bu, Shengqiang Tong. (2018) Chiral ligand exchange countercurrent chromatography: Enantioseparation of amino acids. JOURNAL OF SEPARATION SCIENCE, 41 (6): (1479-1488). [PMID:29323783] [10.1002/jssc.201701117]
37. Zhang Qian, Wang Junsong, Liao Shanting, Li Pei, Xu Dingqiao, Lv Yan, Yang Minghua, Kong Lingyi. (2017) Optimization of Huang-Lian-Jie-Du-Decoction for Ischemic Stroke Treatment and Mechanistic Study by Metabolomic Profiling and Network Analysis. Frontiers in Pharmacology, 8 [PMID:28400733] [10.3389/fphar.2017.00165]
38. Yuanhao Cai, Yulong Chen, Qijie Li, Liang Li, Haoxin Huang, Suying Wang, Weixing Wang. (2017) CO2 Hydrate Formation Promoted by a Natural Amino Acid l-Methionine for Possible Application to CO2 Capture and Storage. Energy Technology, 5 (8): (1195-1199). [10.1002/ente.201600731]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度